Abstract: Various embodiments relate to a microbeam radiation therapy (microbeam radiosurgery) system, including: a radiation beam source; a collimator with slits, wherein the collimator only passes a radiation beam from the radiation beam source through the slits; a filtering and limiting system; a source shutoff controller connected to the radiation beam source; and a detector configured to detect events requiring the shutdown of the radiation beam source.

Abstract: Various embodiments relate to a method of performing microbeam radiation therapy (microbeam radiosurgery) for a subject, including: producing a high-energy radiation beam; shaping, attenuating, strengthening, hardening and/or otherwise appropriately modifying the high-energy radiation beam using a low-Z, high-Z, or variable-Z filter; passing the beam before or after it has been so modified through a collimator to produce high-dose regions alternating with low-dose regions; and irradiating the subject with the collimated beam so modified.

Abstract: Various embodiments relate to a method of performing microbeam radiation therapy on a subject, including: producing a high-energy radiation beam in a first direction; producing planar microbeams using the high-energy radiation beam in the first direction, wherein the microbeams have a width, wherein the planar microbeams produce scattered electrons; and applying a magnetic field in a direction lying in a plane substantially parallel to the planar microbeams, wherein the strength of the magnetic field corresponds to the width of the microbeam.

Abstract: Various embodiments relate to a method of performing microbeam radiation therapy on a subject, including: producing a high-energy radiation beam in a first direction; producing planar microbeams using the high-energy radiation beam in the first direction, wherein the microbeams have a width, wherein the planar microbeams produce scattered electrons; and applying a magnetic field in a direction lying in a plane substantially parallel to the planar microbeams, wherein the strength of the magnetic field corresponds to the width of the microbeam.

Abstract: Various embodiments relate to a microbeam radiation therapy (microbeam radiosurgery) system, including: a radiation beam source; a collimator with slits, wherein the collimator only passes a radiation beam from the radiation beam source through the slits; a filtering and limiting system; a source shutoff controller connected to the radiation beam source; and a detector configured to detect events requiring the shutdown of the radiation beam source.

Abstract: Various embodiments relate to a method of performing microbeam radiation therapy on a subject, including: affixing a collimator to the subject at a first location; producing a first high energy radiation fan beam, wherein the width of the first fan beam in a first direction is greater than the width of the first fan beam in a second direction; and moving the subject in the second direction so that the first fan beam irradiates the subject through the collimator to produce first high dose regions alternating with first low dose regions.

Abstract: Various exemplary embodiments relate to a spinal implant for insertion between two vertebrae including one or more of the following: a cage comprising: a frame including a fastener hole, a lattice structure disposed within the frame and exposed on a top and bottom face of the frame to permit bone growth into the lattice structure, and an inner rim disposed between the lattice structure and a through bore extending through the cage; a bone plate comprising a through hole, and a first and a second screw hole, wherein the first and second screw hole are positioned to overlie the vertebrae when the bone plate is attached to the cage and the cage is inserted between the two vertebrae; and a fastener operable to attach the bone plate to the cage when the fastener is inserted through the through hole of the bone plate and into the fastener hole of the frame.

Abstract: Various embodiments relate to a method of performing microbeam radiation therapy (microbeam radiosurgery) for a subject, including: producing a high-energy radiation beam; shaping, attenuating, strengthening, hardening and/or otherwise appropriately modifying the high-energy radiation beam using a low-Z, high-Z, or variable-Z filter; passing the beam before or after it has been so modified through a collimator to produce high-dose regions alternating with low-dose regions; and irradiating the subject with the collimated beam so modified.

Abstract: Various embodiments relate to a method of performing microbeam radiation therapy on a subject, including: affixing a collimator to the subject at a first location; producing a first high energy radiation fan beam, wherein the width of the first fan beam in a first direction is greater than the width of the first fan beam in a second direction; and moving the subject in the second direction so that the first fan beam irradiates the subject through the collimator to produce first high dose regions alternating with first low dose regions.