Abstract: The present disclosure involves compositions and methods for treating brain cancers having mutations in the retinoblastoma (Rb) pathway using an oncolytic adenovirus comprising an alteration in the Rb binding site of E1A, and a targeting motif inserted in the Ad fiber protein. The adenovirus is able to kill the tumor cells without harming cells with a wild-type retinoblastoma pathway.

Abstract: The present disclosure involves compositions and methods for treating brain cancers having mutations in the retinoblastoma (Rb) pathway using an oncolytic adenovirus comprising an alteration in the Rb binding site of E1A, and a targeting motif inserted in the Ad fiber protein. The adenovirus is able to kill the tumor cells without harming cells with a wild-type retinoblastoma pathway.

Abstract: A portable, mechanically operated, key-duplicating machine that relies on a punch-cutting system that selectively punches out the particular notches or “bittings” of a key blank in response to the details of an adjacent and aligned master key. The duplicating machine comprises a frame having cutting end and an alignment end. The frame defines a longitudinal axis. A carriage is movable along the longitudinal axis and includes a transverse axis. A key clamping assembly has a first key clamp for holding the key blank and a second key clamp for holding the master key. The key assembly is selectively slidable along the transverse axis. A cutting assembly is located at the cutting end and includes a punch-type cutter pin that is adapted to selectively cut pre-shaped notches from the held key blank. The cutter pin includes a guide section that aligns with the notch-profile of the held master key.

Abstract: This invention relates to any fossil fueled thermal system, and especially relates to large commercial steam generators used in power plants, and, more particularly, to a method and apparatus for determining fuel chemistry in essentially real time based on effluents resulting from combustion, associated stoichiometrics, and the genetics of the fossil fuel. Knowing the system's fuel chemistry, the fuel calorific value, the fuel flow and the thermal performance associated with the thermal system may then be determined in essentially real time.

Abstract: A portable, mechanically operated, key-duplicating machine that relies on a punch-cutting system that selectively punches out the particular notches or “bittings” of a key blank in response to the details of an adjacent and aligned master key. The duplicating machine comprises a frame having cutting end and an alignment end. The frame defines a longitudinal axis. A carriage is movable along the longitudinal axis and includes a transverse axis. A key clamping assembly has a first key clamp for holding the key blank and a second key clamp for holding the master key. The key assembly is selectively slidable along the transverse axis. A cutting assembly is located at the cutting end and includes a punch-type cutter pin that is adapted to selectively cut pre-shaped notches from the held key blank. The cutter pin includes a guide section that aligns with the notch-profile of the held master key.

Abstract: Textile materials, including paper webs, treated with a polyvinylamine polymer and a second agent that interacts with the polyvinylamine polymer is disclosed. The second agent added with the polyvinylamine polymer can be, for instance, a polymeric anionic reactive compound or a polymeric aldehyde-functional compound. When incorporated into a paper web, the combination of the polyvinylamine polymer and the second agent provide improved strength properties, such as wet strength properties. In an alternative embodiment, the polyvinylamine polymer and the second polymer can be applied to a textile material for increasing the affinity of the textile material for acid dyes.

Abstract: Textile materials, including paper webs, treated with a polyvinylamine polymer and a second agent that interacts with the polyvinylamine polymer is disclosed. The second agent added with the polyvinylamine polymer can be, for instance, a polymeric anionic reactive compound or a polymeric aldehyde-functional compound. When incorporated into a paper web, the combination of the polyvinylamine polymer and the second agent provide improved strength properties, such as wet strength properties. In an alternative embodiment, the polyvinylamine polymer and the second polymer can be applied to a textile material for increasing the affinity of the textile material for acid dyes.

Abstract: Textile materials, including paper webs, treated with a polyvinylamine polymer and a second agent that interacts with the polyvinylamine polymer is disclosed. The second agent added with the polyvinylamine polymer can be, for instance, a polymeric anionic reactive compound or a polymeric aldehyde-functional compound. When incorporated into a paper web, the combination of the polyvinylamine polymer and the second agent provide improved strength properties, such as wet strength properties. In an alternative embodiment, the polyvinylamine polymer and the second polymer can be applied to a textile material for increasing the affinity of the textile material for acid dyes.