Patents by Inventor Fred S. Lamb

Fred S. Lamb has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITION AND METHODS FOR THE PREVENTION AND TREATMENT OF GASTROINTESTINAL INFECTIONS
    Publication number: 20090258823
    Abstract: Methods for the prevention and treatment of gastrointestinal infections are described. Surfactant-associated protein-A (SP-A) or SP-D or an active fragment or derivative thereof is administered to mammals at risk of a gastrointestinal infection. Oral compositions of SP-A and/or SP-D are disclosed. Also disclosed is a method to prevent or treat a gastrointestinal infection in a mammal using a gene expression vector comprising the SP-A or SP-D structural gene is introduced into a mammalian cell. Also disclosed is a method to prevent or treat a gastrointestinal infection in a mammal by increasing the intestinal expression of endogenous SP-A or SP-D.
    Type: Application
    Filed: December 7, 2007
    Publication date: October 15, 2009
    Inventors: Caroline L.S. George, Jeanne M. Snyder, Fred S. Lamb
  • Use of ClC3 chloride channel blockers to modulate vascular tone
    Patent number: 7393864
    Abstract: The present invention provides methods for the modulation of vascular tone in a patient having compromised vascular tissue, which methods comprise the administration of a chloride channel blocking agent or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: August 15, 2001
    Date of Patent: July 1, 2008
    Assignee: University of Iowa Research Foundation
    Inventors: Fred S. Lamb, Brian C. Schutte, Baoli Yang
  • Methods to reduce the sensitivity of endothelially-compromised vascular smooth muscle
    Patent number: 7220782
    Abstract: The present invention discloses materials and methods useful to treat sensitivity of endothelially-compromised vascular smooth muscle. In one embodiment, CLC3 blockers, particularly compounds of the Formula I are used to treat sensitivity.
    Type: Grant
    Filed: February 25, 2000
    Date of Patent: May 22, 2007
    Assignee: University of Iowa Research Foundation
    Inventor: Fred S. Lamb
  • Use of CLC3 chloride channel blockers to modulate vascular tone
    Publication number: 20020065325
    Abstract: The present invention provides methods for the modulation of vascular tone in a patient having compromised vascular tissue, which methods comprise the administration of a chloride channel blocking agent or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: August 15, 2001
    Publication date: May 30, 2002
    Inventors: Fred S. Lamb, Brian C. Schutte, Baoli Yang