Patents by Inventor Fred W. Starks

Fred W. Starks has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-(phosphonacetyl)-L-aspartic acid salts with piperazine, cyclohexylamine and calcium
    Patent number: 4348522
    Abstract: N-(Phosphonoacetyl)-L-aspartic acid (PALA) compounds, especially novel PALA compounds, and methods for their preparation in large amounts are disclosed. These methods include preparation of certain PALA compounds such as PALA dibenzyl ester, disodium PALA, and the cyclohexylamine salt of dibenzyl PALA.
    Type: Grant
    Filed: May 8, 1981
    Date of Patent: September 7, 1982
    Assignee: Starks Associates, Inc.
    Inventors: Robert J. Schultz, Fred W. Starks
  • N-(Phosphonoacetyl)-L-aspartic acid compounds
    Patent number: 4267126
    Abstract: N-(Phosphonoacetyl)-L-aspartic acid (PALA) compounds, especially novel PALA compounds, and methods for their preparation in large amounts are disclosed. These methods include preparation of certain PALA compounds such as PALA dibenzyl ester, disodium PALA, and the cyclohexylamine salt of dibenzyl PALA.
    Type: Grant
    Filed: January 23, 1980
    Date of Patent: May 12, 1981
    Assignee: Starks Associates, Inc.
    Inventors: Robert J. Schultz, Fred W. Starks
  • Multi-step process for the production of methanesulfon-m-anisidide, 4'-(9-acridinylamino)-
    Patent number: 4258191
    Abstract: A multi-step method of producing the compound methanesulfon-m-anisidide, 4'-(9-acridinylamino)-, acetate (VII), which may be in free base form and designated NSC 249992, also known as AMSA. This compound is produced by an elegant process from a starting material, 4-butyrylamino-3-methoxy-nitrobenzene, which is later transformed to methanesulfon-m-anisidide, 4'-amino- (IV) and is coupled or joined to 9-chloro-acridine, producing the chloride salt which is later converted to the acetate.
    Type: Grant
    Filed: March 29, 1979
    Date of Patent: March 24, 1981
    Assignee: The United States of America as represented by the Secretary of Health, Education and Welfare
    Inventors: Henryk Dubicki, Jack L. Parsons, Fred W. Starks
  • N-(Phosphonoacetyl)-L-aspartic acid compounds and methods for their preparation
    Patent number: 4215070
    Abstract: N-(Phosphonoacetyl)-L-aspartic acid (PALA) compounds, especially novel PALA compounds, and methods for their preparation in large amounts are disclosed. These methods include preparation of certain PALA compounds such as PALA dibenzyl ester, disodium PALA, and the cyclohexylamine salt of dibenzyl PALA.
    Type: Grant
    Filed: October 25, 1978
    Date of Patent: July 29, 1980
    Assignee: Starks Associates, Inc.
    Inventors: Robert J. Schultz, Fred W. Starks
  • Preparation of N-(phosphonoacetyl)-L-aspartic acid
    Patent number: 4179464
    Abstract: Improved methods for preparation of the tetrasodium and disodium salts of N-(phosphonoacetyl)-L-aspartic acid (PALA) are disclosed. The present methods are well suited for preparation of these products in large amounts. Particular aspects of these methods include: (1) initial preparation of the PALA moiety as the dibenzyl ester; (2) the complete removal of impurities in the form of acetic acid and sodium acetate from disodium PALA by turbulent flow precipitation; and (3) preparation and purification of the cyclohexylammonium salt of dibenzyl PALA which ultimately results in a purer final product.
    Type: Grant
    Filed: August 10, 1978
    Date of Patent: December 18, 1979
    Inventors: Robert J. Schultz, Fred W. Starks