Patents by Inventor Freda Stevenson

Freda Stevenson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Materials and methods relating to immune responses to fusion proteins
    Patent number: 7816334
    Abstract: The invention provides nucleic acid construct and nucleic acid expression vectors directing the expression of a fusion protein consisting of a disease peptide antigen and a first domain of FrC of tetanus toxin. The invention provides nucleic acid (DNA) vaccines for use in inducing an immune response against a disease. There is also provided methods of producing nucleic acid constructs and vectors for use as nucleic acid (DNA) vaccines.
    Type: Grant
    Filed: April 17, 2001
    Date of Patent: October 19, 2010
    Assignee: Cancer Research Technology Limited
    Inventors: Jason Rice, Freda Stevenson
  • Materials and methods relating to fusion proteins for inducing an immune response
    Patent number: 7410643
    Abstract: A nucleic acid construct is provided for delivery into living cells in vivo for inducing an immune response in a patient to an antigen; the construct directing the expression of a fusion protein, said fusion protein comprising said antigen and an adjuvant sequence derived from a plant viral coat protein. Methods for making constructs and methods of using such constructs for the treatment of infectious disease, cancer and B cell malignancy, are provided.
    Type: Grant
    Filed: January 10, 2007
    Date of Patent: August 12, 2008
    Assignee: Cancer Research Technology Limited
    Inventors: Natalia Savelyeva, Freda Stevenson
  • Materials and methods relating to DNA vaccination
    Publication number: 20070253969
    Abstract: The present invention provides improved methods relating to DNA vaccination, particularly in relation to boosting the immune response. The inventors provide methods of immunizing an individual against an antigen, e.g. a tumor antigen using electroporation as a method of administration.
    Type: Application
    Filed: November 14, 2006
    Publication date: November 1, 2007
    Inventors: Freda Stevenson, Jason Rice, Sarah Buchan
  • Materials and methods relating to fusion proteins for inducing an immune response
    Publication number: 20070128220
    Abstract: A nucleic acid construct is provided for delivery into living cells in vivo for inducing an immune response in a patient to an antigen; the construct directing the expression of a fusion protein, said fusion protein comprising said antigen and an adjuvant sequence derived from a plant viral coat protein. Methods for making constructs and methods of using such constructs for the treatment of infectious disease, cancer and B cell malignancy, are provided.
    Type: Application
    Filed: January 10, 2007
    Publication date: June 7, 2007
    Inventors: Natalia Savelyeva, Freda Stevenson
  • Materials and methods relating to fusion proteins an immune response
    Patent number: 7179471
    Abstract: A nucleic acid construct is provided for delivery into living cells in vivo for inducing an immune response in a patient to an antigen; the construct directing the expression of a fusion protein, said fusion protein comprising said antigen and an adjuvant sequence derived from a plant viral coat protein. Methods for making such constructs, and methods of using such constructs for the treatment of infectious disease, cancer and B cell malignancy, are provided.
    Type: Grant
    Filed: November 20, 2001
    Date of Patent: February 20, 2007
    Assignee: Cancer Research Ventures Limited
    Inventors: Natalia Savelyeva, Freda Stevenson
  • Materials and methods relating to fusion proteins an immune response
    Publication number: 20040072781
    Abstract: A nucleic acid construct is provided for delivery into living cells in vivo for inducing an immune response in a patient to an antigen; the construct directing the expression of a fusion protein, said fusion protein comprising said antigen and an adjuvant sequence derived from a plant viral coat protein. Methods for making such constructs, and methods of using such constructs for the treatment of infectious disease, cancer and B cell malignancy, are provided.
    Type: Application
    Filed: October 27, 2003
    Publication date: April 15, 2004
    Inventors: Natalia Savelyeva, Freda Stevenson
  • Materials and methods relating to immune responses to fusion proteins
    Publication number: 20030158136
    Abstract: The invention provides nuecleic acid construct and nucleic acid expression vectors directing the expression of a fusion protein consisting or a disease peptide antigen and a first, domain of FrC of tetanus toxin. The invention provides nucleic acid (DNA) vaccines for use in inducing an immune response against a disease. There is also provided methods of producing nucleic acid constructs and vectors for use as nucleic acid (DNA) vaccines.
    Type: Application
    Filed: March 27, 2003
    Publication date: August 21, 2003
    Inventors: Jason Rice, Freda Stevenson