Patents by Inventor Frederic Avery Bourke, Jr.

Frederic Avery Bourke, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10213763
    Abstract: A method and a system for producing a change in a medium disposed in an artificial container. The method places in a vicinity of the medium at least one of a plasmonics agent and an energy modulation agent. The method applies an initiation energy through the artificial container to the medium. The initiation energy interacts with the plasmonics agent or the energy modulation agent to directly or indirectly produce the change in the medium. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the plasmonics agent or the energy modulation agent.
    Type: Grant
    Filed: January 17, 2017
    Date of Patent: February 26, 2019
    Assignees: IMMUNOLIGHT, LLC., DUKE UNIVERSITY
    Inventors: Frederic Avery Bourke, Jr., Tuan Vo-Dinh
  • Patent number: 10201796
    Abstract: A method and a system for producing a change in a medium disposed in an artificial container. The method places in a vicinity of the medium at least one of a plasmonics agent and an energy modulation agent. The method applies an initiation energy through the artificial container to the medium. The initiation energy interacts with the plasmonics agent or the energy modulation agent to directly or indirectly produce the change in the medium. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the plasmonics agent or the energy modulation agent.
    Type: Grant
    Filed: February 27, 2017
    Date of Patent: February 12, 2019
    Assignees: IMMUNOLIGHT, LLC., DUKE UNIVERSITY
    Inventors: Frederic Avery Bourke, Jr., Tuan Vo-Dinh
  • Patent number: 10087343
    Abstract: A method of and system for adhesive bonding. The method and system a) treat a surface of an element to be bonded to provide an adherent structure including one or more rubber compounds on the surface; b) place a polymerizable adhesive composition, including at least one photoinitiator and at least one energy converting material, in contact with the adherent structure and two or more components to be bonded to form an assembly, c) irradiated the assembly with radiation at a first wavelength, capable of conversion by the at least one energy converting material, to a second wavelength capable of activating the at least one photoinitiator to produce from the polymerizable adhesive composition a cured adhesive composition; and d) adhesively join the two or more components by way of the adherent structure and the cured adhesive composition.
    Type: Grant
    Filed: March 18, 2015
    Date of Patent: October 2, 2018
    Assignee: IMMUNOLIGHT, LLC
    Inventors: Zakaryae Fathi, Frederic Avery Bourke, Jr., Harold Walder
  • Patent number: 9943094
    Abstract: A method and a system for producing a change in a medium. The method places in a vicinity of the medium an energy modulation agent. The method applies an initiation energy to the medium. The initiation energy interacts with the energy modulation agent to directly or indirectly produce the change in the medium. The energy modulation agent has a normal predominant emission of radiation in a first wavelength range outside of a second wavelength range (WR2) known to produce the change, but under exposure to the applied initiation energy produces the change. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the energy modulation agent.
    Type: Grant
    Filed: October 11, 2016
    Date of Patent: April 17, 2018
    Assignee: IMMUNOLIGHT, LLC.
    Inventors: Frederic Avery Bourke, Jr., Zakaryae Fathi, Harold Walder, Wayne F. Beyer, Jr.
  • Publication number: 20170173350
    Abstract: A method and a system for producing a change in a medium disposed in an artificial container. The method places in a vicinity of the medium at least one of a plasmonics agent and an energy modulation agent. The method applies an initiation energy through the artificial container to the medium. The initiation energy interacts with the plasmonics agent or the energy modulation agent to directly or indirectly produce the change in the medium. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the plasmonics agent or the energy modulation agent.
    Type: Application
    Filed: February 27, 2017
    Publication date: June 22, 2017
    Applicants: IMMUNOLIGHT, LLC., DUKE UNIVERSITY
    Inventors: Frederic Avery Bourke, JR., Tuan Vo-Dinh
  • Publication number: 20170121472
    Abstract: A method and a system for producing a change in a medium disposed in an artificial container. The method places in a vicinity of the medium at least one of a plasmonics agent and an energy modulation agent. The method applies an initiation energy through the artificial container to the medium. The initiation energy interacts with the plasmonics agent or the energy modulation agent to directly or indirectly produce the change in the medium. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the plasmonics agent or the energy modulation agent.
    Type: Application
    Filed: January 17, 2017
    Publication date: May 4, 2017
    Applicants: IMMUNOLIGHT, LLC., DUKE UNIVERSITY
    Inventors: Frederic Avery BOURKE, JR., Tuan Vo-Dinh
  • Patent number: 9630022
    Abstract: A method and a system for producing a change in a medium disposed in an artificial container. The method places in a vicinity of the medium at least one of a plasmonics agent and an energy modulation agent. The method applies an initiation energy through the artificial container to the medium. The initiation energy interacts with the plasmonics agent or the energy modulation agent to directly or indirectly produce the change in the medium. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the plasmonics agent or the energy modulation agent.
    Type: Grant
    Filed: January 27, 2014
    Date of Patent: April 25, 2017
    Assignees: IMMUNOLIGHT, LLC., DUKE UNIVERSITY
    Inventors: Frederic Avery Bourke, Jr., Tuan Vo-Dinh
  • Patent number: 9579523
    Abstract: A method and a system for producing a change in a medium disposed in an artificial container. The method places in a vicinity of the medium at least one of a plasmonics agent and an energy modulation agent. The method applies an initiation energy through the artificial container to the medium. The initiation energy interacts with the plasmonics agent or the energy modulation agent to directly or indirectly produce the change in the medium. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the plasmonics agent or the energy modulation agent.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: February 28, 2017
    Assignees: IMMUNOLIGHT, LLC, DUKE UNIVERSITY
    Inventors: Frederic Avery Bourke, Jr., Tuan Vo-Dinh
  • Publication number: 20170027197
    Abstract: A method and a system for producing a change in a medium. The method places in a vicinity of the medium an energy modulation agent. The method applies an initiation energy to the medium. The initiation energy interacts with the energy modulation agent to directly or indirectly produce the change in the medium. The energy modulation agent has a normal predominant emission of radiation in a first wavelength range outside of a second wavelength range (WR2) known to produce the change, but under exposure to the applied initiation energy produces the change. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the energy modulation agent.
    Type: Application
    Filed: October 11, 2016
    Publication date: February 2, 2017
    Applicant: IMMUNOLIGHT, LLC.
    Inventors: FREDERIC AVERY BOURKE, JR., ZAKARYAE FATHI, HAROLD WALDER, WAYNE F. BEYER, JR.
  • Patent number: 9488916
    Abstract: A method and a system for producing a change in a medium. The method places in a vicinity of the medium an energy modulation agent. The method applies an initiation energy to the medium. The initiation energy interacts with the energy modulation agent to directly or indirectly produce the change in the medium. The energy modulation agent has a normal predominant emission of radiation in a first wavelength range outside of a second wavelength range (WR2) known to produce the change, but under exposure to the applied initiation energy produces the change. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the energy modulation agent.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: November 8, 2016
    Assignee: IMMUNOLIGHT, LLC.
    Inventors: Frederic Avery Bourke, Jr., Zakaryae Fathi, Harold Walder, Wayne F. Beyer, Jr.
  • Patent number: 9352040
    Abstract: Methods for the treatment of a cell proliferation disorder in a subject, involving: (1) administering to the subject at least one activatable pharmaceutical agent that is capable of effecting a predetermined cellular change when activated, either alone or in combination with at least one energy modulation agent; and (2) applying an initiation energy from an initiation energy source to the subject, wherein the applying activates the activatable agent in situ, thus causing the predetermined cellular change to occur, wherein the predetermined cellular change treats the cell proliferation disorder, preferably by causing an increase or decrease in rate of cell proliferation, and a kit for performing the method, a computer implemented system for performing the method, a pharmaceutical composition useful in the method and a method for causing an autovaccine effect in a subject using the method.
    Type: Grant
    Filed: April 4, 2014
    Date of Patent: May 31, 2016
    Assignee: IMMUNOLIGHT, LLC.
    Inventor: Frederic Avery Bourke, Jr.
  • Patent number: 9174190
    Abstract: A method and a system for producing a change in a medium disposed in an artificial container. The method places in a vicinity of the medium at least one of a plasmonics agent and an energy modulation agent. The method applies an initiation energy through the artificial container to the medium. The initiation energy interacts with the plasmonics agent or the energy modulation agent to directly or indirectly produce the change in the medium. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the plasmonics agent or the energy modulation agent.
    Type: Grant
    Filed: April 4, 2014
    Date of Patent: November 3, 2015
    Assignees: IMMUNOLIGHT, LLC, DUKE UNIVERSITY
    Inventors: Frederic Avery Bourke, Jr., Tuan Vo-Dinh
  • Patent number: 9004131
    Abstract: A method and a system for producing a change in a medium disposed in an artificial container. The method places in a vicinity of the medium at least one of a plasmonics agent and an energy modulation agent. The method applies an initiation energy through the artificial container to the medium. The initiation energy interacts with the plasmonics agent or the energy modulation agent to directly or indirectly produce the change in the medium. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the plasmonics agent or the energy modulation agent.
    Type: Grant
    Filed: December 13, 2012
    Date of Patent: April 14, 2015
    Assignees: Duke University, Immunolight, LLC
    Inventors: Frederic Avery Bourke, Jr., Tuan Vo-Dinh
  • Patent number: 8927615
    Abstract: A method and a system for producing a change in a medium disposed in an artificial container. The method places in a vicinity of the medium at least one of a plasmonics agent and an energy modulation agent. The method applies an initiation energy through the artificial container to the medium. The initiation energy interacts with the plasmonics agent or the energy modulation agent to directly or indirectly produce the change in the medium. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the plasmonics agent or the energy modulation agent.
    Type: Grant
    Filed: May 8, 2013
    Date of Patent: January 6, 2015
    Assignees: Immunolight, LLC, Duke University
    Inventors: Frederic Avery Bourke, Jr., Tuan Vo-Dinh
  • Publication number: 20140272030
    Abstract: A method and a system for producing a change in a medium. The method places in a vicinity of the medium an energy modulation agent. The method applies an initiation energy to the medium. The initiation energy interacts with the energy modulation agent to directly or indirectly produce the change in the medium. The energy modulation agent has a normal predominant emission of radiation in a first wavelength range outside of a second wavelength range (WR2) known to produce the change, but under exposure to the applied initiation energy produces the change. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the energy modulation agent.
    Type: Application
    Filed: March 12, 2014
    Publication date: September 18, 2014
    Applicant: IMMUNOLIGHT, LLC.
    Inventors: Frederic Avery Bourke, JR., Zakaryae Fathi, Harold Walder, Wayne F. Beyer, JR.
  • Publication number: 20140242035
    Abstract: Methods for the treatment of a cell proliferation disorder in a subject, involving: (1) administering to the subject at least one activatable pharmaceutical agent that is capable of effecting a predetermined cellular change when activated, either alone or in combination with at least one energy modulation agent; and (2) applying an initiation energy from an initiation energy source to the subject, wherein the applying activates the activatable agent in situ, thus causing the predetermined cellular change to occur, wherein the predetermined cellular change treats the cell proliferation disorder, preferably by causing an increase or decrease in rate of cell proliferation, and a kit for performing the method, a computer implemented system for performing the method, a pharmaceutical composition useful in the method and a method for causing an autovaccine effect in a subject using the method.
    Type: Application
    Filed: April 4, 2014
    Publication date: August 28, 2014
    Applicant: IMMUNOLIGHT, LLC.
    Inventor: Frederic Avery Bourke, JR.
  • Publication number: 20140222117
    Abstract: A method and a system for producing a change in a medium disposed in an artificial container. The method places in a vicinity of the medium at least one of a plasmonics agent and an energy modulation agent. The method applies an initiation energy through the artificial container to the medium. The initiation energy interacts with the plasmonics agent or the energy modulation agent to directly or indirectly produce the change in the medium. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the plasmonics agent or the energy modulation agent.
    Type: Application
    Filed: April 4, 2014
    Publication date: August 7, 2014
    Applicants: DUKE UNIVERSITY, IMMUNOLIGHT, LLC.
    Inventors: Frederic Avery Bourke, JR., Tuan Vo-Dinh
  • Publication number: 20140163303
    Abstract: A method and a system for producing a change in a medium disposed in an artificial container. The method places in a vicinity of the medium at least one of a plasmonics agent and an energy modulation agent. The method applies an initiation energy through the artificial container to the medium. The initiation energy interacts with the plasmonics agent or the energy modulation agent to directly or indirectly produce the change in the medium. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the plasmonics agent or the energy modulation agent.
    Type: Application
    Filed: January 27, 2014
    Publication date: June 12, 2014
    Applicants: DUKE UNIVERSITY, IMMUNOLIGHT, LLC.
    Inventors: Frederic Avery BOURKE, JR., Tuan VO-DINH
  • Publication number: 20130240758
    Abstract: A method and a system for producing a change in a medium disposed in an artificial container. The method places in a vicinity of the medium at least one of a plasmonics agent and an energy modulation agent. The method applies an initiation energy through the artificial container to the medium. The initiation energy interacts with the plasmonics agent or the energy modulation agent to directly or indirectly produce the change in the medium. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the plasmonics agent or the energy modulation agent.
    Type: Application
    Filed: May 8, 2013
    Publication date: September 19, 2013
    Applicant: IMMUNOLIGHT, LLC
    Inventors: Frederic Avery Bourke, JR., Tuan Vo-Dinh
  • Patent number: 8376013
    Abstract: A method and a system for producing a change in a medium disposed in an artificial container. The method places in a vicinity of the medium at least one of a plasmonics agent and an energy modulation agent. The method applies an initiation energy through the artificial container to the medium. The initiation energy interacts with the plasmonics agent or the energy modulation agent to directly or indirectly produce the change in the medium. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the plasmonics agent or the energy modulation agent.
    Type: Grant
    Filed: March 10, 2009
    Date of Patent: February 19, 2013
    Assignees: Duke University, Immunolight, LLC
    Inventors: Frederic Avery Bourke, Jr., Tuan Vo-Dinh