Patents by Inventor Frederic Boschetti

Frederic Boschetti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of imidazo[1,2-a]pyrazin-4-ium salts for the synthesis of 1,4,7-triazacyclononane (tacn) and N- and/or C- functionalized derivatives thereof
    Patent number: 9988388
    Abstract: A compound with formula (V?) the synthesis method for compound (V?), and its use for the preparation of 1,4,7-triazacyclononane (tacn) and N- and/or C-functionalized derivatives thereof, particularly compounds with formula (I) Also, metallic complexes comprising a ligand with formula (I) and a metal and their use for imaging.
    Type: Grant
    Filed: April 7, 2016
    Date of Patent: June 5, 2018
    Assignees: UNIVERSITE DE BOURGOGNE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Franck Denat, Pauline Desogere, Claire Bernhard, Yoann Rousselin, Frederic Boschetti
  • Synthesis of imidazo[1,2-a]pyrazin-4-ium salts for the synthesis of 1,4,7-triazacyclononane (tacn) and N- and/or C-functionalized derivatives thereof
    Patent number: 9981967
    Abstract: The present invention embodiments relate to a compound with formula (V?) The invention also relates in certain embodiments to the synthesis method for compound (V?) and its use for the preparation of 1,4,7-triazacyclononane (tacn) and N- and/or C-functionalized derivatives thereof, particularly compounds with formula (I) The invention also relates in certain embodiments to metallic complexes comprising a ligand with formula (I) and a metal and their use for imaging.
    Type: Grant
    Filed: November 13, 2013
    Date of Patent: May 29, 2018
    Assignees: UNIVERSITE DE BOURGOGNE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Franck Denat, Pauline Desogere, Claire Bernhard, Yoann Rousselin, Frederic Boschetti
  • SYNTHESIS OF IMIDAZO[1,2-a]PYRAZIN-4-IUM SALTS FOR THE SYNTHESIS OF 1,4,7-TRIAZACYCLONONANE (TACN) AND N- AND/OR C- FUNCTIONALIZED DERIVATIVES THEREOF
    Publication number: 20160222018
    Abstract: A compound with formula (V?) the synthesis method for compound (V?), and its use for the preparation of 1,4,7-triazacyclononane (tacn) and N- and/or C-functionalized derivatives thereof, particularly compounds with formula (I) Also, metallic complexes comprising a ligand with formula (I) and a metal and their use for imaging.
    Type: Application
    Filed: April 7, 2016
    Publication date: August 4, 2016
    Inventors: Franck DENAT, Pauline DESOGERE, Claire BERNHARD, Yoann Rousselin, Frederic BOSCHETTI
  • Materials for the solid/liquid extraction of heavy metal ions, containing supported N-functionalized polyazacycloalkanes
    Patent number: 8975395
    Abstract: The present invention relates to a material notably adapted for the extraction of metal cations in an aqueous medium, comprising a solid support on which are attached polyazacycloalkane compounds having a ring including at least 4 nitrogen atoms, and wherein the nitrogen atoms of the ring are substituted with coordinating groups, which each are independently: a coordinating group of formula: —(CH2)n—C(?O)—NR1R2 ?or else a both coordinating and binding group, fitting the formula: —(CH2)p—C(?O)—NR3-(A)-[support]. The invention also relates to methods for preparing the aforementioned materials and to different uses thereof, notably for the extraction of Pb2+ cations in an aqueous medium.
    Type: Grant
    Filed: February 20, 2009
    Date of Patent: March 10, 2015
    Assignee: Centre National de la Recherche Scientifique (C.N.R.S.)
    Inventors: Michel Meyer, Arnaud Bucaille, Francois Cuenot, Franck Denat, Frédéric Boschetti, Roger Guilard
  • SYNTHESIS OF IMIDAZO[1,2-a]PYRAZIN-4-IUM SALTS FOR THE SYNTHESIS OF 1,4,7-TRIAZACYCLONONANE (TACN) AND N- AND/OR C-FUNCTIONALIZED DERIVATIVES THEREOF
    Publication number: 20140142298
    Abstract: The present invention embodiments relate to a compound with formula (V?) The invention also relates in certain embodiments to the synthesis method for compound (V?) and its use for the preparation of 1,4,7-triazacyclononane (tacn) and N- and/or C-functionalized derivatives thereof, particularly compounds with formula (I) The invention also relates in certain embodiments to metallic complexes comprising a ligand with formula (I) and a metal and their use for imaging.
    Type: Application
    Filed: November 13, 2013
    Publication date: May 22, 2014
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DE BOURGOGNE
    Inventors: Franck Denat, Pauline Desogere, Claire Bernhard, Yoann Rousselin, Frederic Boschetti
  • MATERIALS FOR THE SOLID/LIQUID EXTRACTION OF HEAVY METAL IONS, CONTAINING SUPPORTED N-FUNCTIONALIZED POLYAZACYLOALKANES
    Publication number: 20110079557
    Abstract: The present invention relates to a material notably adapted for the extraction of metal cations in an aqueous medium, comprising a solid support on which are attached polyazacycloalkane compounds having a ring including at least 4 nitrogen atoms, and wherein the nitrogen atoms of the ring are substituted with coordinating groups, which each are independently: a coordinating group of formula: —(CH2)n—C(?O)—NR1R2 ?or else a both coordinating and binding group, fitting the formula: —(CH2)p—C(?O)—NR3-(A)-[support]. The invention also relates to methods for preparing the aforementioned materials and to different uses thereof, notably for the extraction of Pb2+ cations in an aqueous medium.
    Type: Application
    Filed: February 20, 2009
    Publication date: April 7, 2011
    Inventors: Michel Meyer, Arnaud Bucaille, Francois Cuenot, Franck Denat, Frédéric Boschetti, Roger Guilard
  • Method of preparing cis-8b-methyldecahydro-2a,4a,6a,8a-tetraazacyclopenta[fg]acenaphthylene, cis-decahydro-2a,4a,6a,8a-tetraazacyclopenta[fg]acenaphthylene, cyclene and functionalised cyclenes
    Patent number: 7659393
    Abstract: A method of preparing cyclene having formula (I) from triethylenetetraamine having formula (VIII) or ethylenediamine having formula (VIII?) includes a series of steps. The first series of steps (I) includes a step A (one-pot preparation of the compound having formula (IIa) from the compound having formula (VIII)), followed by a step B (transforming the compound having formula (IIa) into cyclene having formula (I)). The second series of steps (II) includes a step C (preparing the compound having formula (IIb) from the compound having formula (VIII)), followed by a step D (transforming the compound having formula (IIb) into cylcene having formula (I)). The third series of steps (III) includes a step E involving the onepot preparation of the compound having formula (IIa) from the compound having formula (VIII), followed by a step B involving the transformation of the compound having formula (IIa) into cyclene having formula (I).
    Type: Grant
    Filed: June 4, 2004
    Date of Patent: February 9, 2010
    Assignee: Centre National de la Recherche Scientifique (C.N.R.S.)
    Inventors: Frederic Boschetti, Fanny Chaux, Franck Denat, Roger Guilard, Henry Ledon
  • Method of preparing nitrogen macrocycles
    Patent number: 7312327
    Abstract: The invention relates to a method of preparing nitrogen macrocycles having formula (I). The inventive method comprises a step involving the reaction of compounds (II) and (III) in order to form a compound having formula (IV). Said compound is subsequently made to react with a compound having formula (V) in order to form a compound having formula (VI).
    Type: Grant
    Filed: September 27, 2002
    Date of Patent: December 25, 2007
    Assignees: Centre National de la Recherche Scientifique (C.N.R.S.), Commissariat a l'energie Atomique
    Inventors: Frederic Boschetti, Franck Denat, Roger Guilard, Henry Ledon, Herve Chollet, Jean-Louis Babouhot
  • Method of preparing cis-8b-methyldecahydro-2a,4a,6a,8a-tetraazacyclopenta[fg] acenaphthylene, cis-decahydro-2a,4a,6a,8a-tetraazacyclopenta[fg] acenaphthylene, cyclene and functionalised cyclenes
    Publication number: 20060217548
    Abstract: A method of preparing cyclene having formula (I) from triethylenetetraamine having formula (VIII) or ethylenediamine having formula (VIII?) includes a series of steps. The first series of steps (I) includes a step A (one-pot preparation of the compound having formula (IIa) from the compound having formula (VIII)), followed by a step B (transforming the compound having formula (IIa) into cyclene having formula (I)). The second series of steps (II) includes a step C (preparing the compound having formula (IIb) from the compound having formula (VIII)), followed by a step D (transforming the compound having formula (IIb) into cylcene having formula (I)). The third series of steps (III) includes a step E involving the one-pot preparation of the compound having formula (IIa) from the compound having formula (VIII), followed by a step B involving the transformation of the compound having formula (IIa) into cyclene having formula (I).
    Type: Application
    Filed: June 4, 2004
    Publication date: September 28, 2006
    Inventors: Frèderic Boschetti, Fanny Chaux, Franck Denat, Roger Guilard, Henry Ledon
  • Novel method of preparing nitrogen macrocycles
    Publication number: 20040206940
    Abstract: The invention relates to a method of preparing nitrogen macrocycles having formula (I). The inventive method comprises a step involving the reaction of compounds (II) and (III) in order to form a compound having formula (IV). Said compound is subsequently made to react with a compound having formula (V) in order to form a compound having formula (VI).
    Type: Application
    Filed: March 26, 2004
    Publication date: October 21, 2004
    Inventors: Frederic Boschetti, Franck Denat, Roger Guilard, Henry Ledon, Herve Chollet, Jean-Louis Babouhot