Patents by Inventor Frederic Bottausci
Frederic Bottausci has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11692960Abstract: An electrochemical measurement cartridge includes a container including a first analysis chamber for receiving a fluid to be analyzed and a second calibration chamber for receiving a calibration fluid; an electrochemical measurement sensor including at least one work electrode and one reference electrode; a container supporting the sensor and a cover arranged mobile relative to one another to confer on the cartridge at least two separate operating configurations, a first configuration in which the sensor is communicating with the first analysis chamber and a second configuration in which the sensor is communicating with the second calibration chamber; sealing between the chambers of the container and the cover; and a drive member for providing a relative movement of the container relative to the cover.Type: GrantFiled: May 24, 2018Date of Patent: July 4, 2023Assignee: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Eric Gouze, Frederic Bottausci, Pascal Mailley, Olivier Fuchs
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Patent number: 11426106Abstract: A medical drain sensor is provided located in a region of a drain tube which has turbulent or re-circulatory exudate flow. Means are provided in some embodiments to promote or enhance such flow.Type: GrantFiled: May 1, 2018Date of Patent: August 30, 2022Assignees: Sofradim Production, CEA (Commissariat A L'energie Atomique Et Aux Energies Alternatives)Inventors: Yves Bayon, Dagmar Guyader, Maxime Gougis, Mélanie Alias, Séverine Vignoud, Frederic Bottausci, Pascal Mailley
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Publication number: 20220168232Abstract: A capsule including alginate encapsulating: insulin-secreting cells, a RGD-alginate, mesenchymal stem cells, extracellular matrix, the process for the preparation thereof and the use thereof for treating diabetes.Type: ApplicationFiled: March 27, 2020Publication date: June 2, 2022Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE GRENOBLE ALPES, ETABLISSEMENT FRANCAIS DU SANG, WAKE FOREST UNIVERSITY HEALTH SCIENCESInventors: Sandrine LABLANCHE, Pierre-Yves BENHAMOU, Emily TUBBS, Anaïck MOISAN, Harald EGELHOFER, Virginie PERSOONS, Florence RIVERA, Frédéric BOTTAUSCI, Maxime PIERRON, Giuseppe ORLANDO, Riccardo TAMBURRINI
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Publication number: 20210178131Abstract: In a surgical drain system formed with two or more branches, exudate flow from a patient's wound is directed between two branches with the respective filling and emptying times determined in order to identify the presence of a blockage in the drain.Type: ApplicationFiled: February 19, 2021Publication date: June 17, 2021Inventors: Yves Bayon, Dagmar Guyader, Maxime Gougis, Severine Vignoud, Frederic Bottausci, Pascal Mailley
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Resonant chemical sensor comprising a functionalisation device and method for the production thereof
Patent number: 10983093Abstract: A chemical sensor including at least one resonant detection structure, the detection structure including at least one layer based on a porous material, the pores of which are covered with at least one functionalization layer that can adsorb or absorb at least one chemical species.Type: GrantFiled: July 25, 2017Date of Patent: April 20, 2021Assignee: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Thierry Claret, Frederic Bottausci, Guy-Michel Parat, Severine Vignoud -
Patent number: 10953207Abstract: In a surgical drain system formed with two or more branches, exudate flow from a patient's wound is directed between two branches with the respective filling and emptying times determined in order to identify the presence of a blockage in the drain.Type: GrantFiled: May 1, 2018Date of Patent: March 23, 2021Assignees: Sofradim, CEA (Commissariat A L'energie Atomique Et Aux Energies Alternatives)Inventors: Yves Bayon, Dagmar Guyader, Maxime Gougis, Séverine Vignoud, Frederic Bottausci, Pascal Mailley
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Publication number: 20200173950Abstract: An electrochemical measurement cartridge includes a container including a first analysis chamber for receiving a fluid to be analyzed and a second calibration chamber for receiving a calibration fluid; an electrochemical measurement sensor including at least one work electrode and one reference electrode; a container supporting the sensor and a cover arranged mobile relative to one another to confer on the cartridge at least two separate operating configurations, a first configuration in which the sensor is communicating with the first analysis chamber and a second configuration in which the sensor is communicating with the second calibration chamber; sealing between the chambers of the container and the cover; and a drive member for providing a relative movement of the container relative to the coverType: ApplicationFiled: May 24, 2018Publication date: June 4, 2020Applicant: Commissariat à l 'énergie atomique et aux énergies alternativesInventors: Eric GOUZE, Frederic BOTTAUSCI, Pascal MAILLEY, Olivier FUCHS
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Publication number: 20180338714Abstract: A medical drain sensor is provided located in a region of a drain tube which has turbulent or re-circulatory exudate flow. Means are provided in some embodiments to promote or enhance such flow.Type: ApplicationFiled: May 1, 2018Publication date: November 29, 2018Inventors: Yves Bayon, Dagmar Guyader, Maxime Gougis, Mélanie Alias, Séverine Vignoud, Frederic Bottausci, Pascal Mailley
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Publication number: 20180339140Abstract: In a surgical drain system formed with two or more branches, exudate flow from a patient's wound is directed between two branches with the respective filling and emptying times determined in order to identify the presence of a blockage in the drain.Type: ApplicationFiled: May 1, 2018Publication date: November 29, 2018Inventors: Yves Bayon, Dagmar Guyader, Maxime Gougis, Séverine Vignoud, Frederic Bottausci, Pascal Mailley
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Publication number: 20140174992Abstract: Particles are separated, concentrated, or mixed within a fluid by means of a fluid-containing cell having a longitudinal axis, a cross-sectional area generally perpendicular to the longitudinal axis, and at least one particle motivating force directionally interacting with at least one recurrent circulating fluid flow generally aligned with the longitudinal axis within the fluid containing cell.Type: ApplicationFiled: August 20, 2013Publication date: June 26, 2014Applicant: The Regents of the University of CaliforniaInventors: Igor Mezic, Frederic Bottausci, Idan Tuval
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Publication number: 20120298512Abstract: An apparatus, a method and a process to achieve manipulation of particles and/or solutions through the use of electrokinetic properties are disclosed. The manipulation is performed using a disposable device positioned on top of a stage for purposes of powering the electrodes. The fluidic solution is brought into contact with the active part of the device and then manipulated.Type: ApplicationFiled: July 30, 2012Publication date: November 29, 2012Applicant: The Regents of the University of CaliforniaInventors: Igor Mezic, Frederic Bottausci, Jason S. Spievak, Peter J. Strand
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Patent number: 8246802Abstract: An apparatus, a method and a process to achieve manipulation of particles and/or solutions through the use of electrokinetic properties are disclosed. The manipulation is performed using a disposable device positioned on top of a stage for purposes of powering the electrodes. The fluidic solution is brought into contact with the active part of the device and then manipulated.Type: GrantFiled: May 14, 2008Date of Patent: August 21, 2012Assignee: The Regents of the University of CaliforniaInventors: Igor Mezic, Frederic Bottausci, Jason S. Spievak, Peter J. Strand
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Patent number: 8182669Abstract: Particles are separated, concentrated, or mixed within a fluid by means of a fluid-containing cell having a longitudinal axis, a cross-sectional area generally perpendicular to the longitudinal axis, and at least one particle motivating force directionally interacting with at least one recurrent circulating fluid flow generally aligned with the longitudinal axis within the fluid containing cell.Type: GrantFiled: November 17, 2006Date of Patent: May 22, 2012Assignee: The Regents of the University of CaliforniaInventors: Igor Mezic, Frederic Bottausci, Idan Tuval
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Publication number: 20110073531Abstract: Particles are separated, concentrated, or mixed within a fluid by means of a fluid-containing cell having a longitudinal axis, a cross-sectional area generally perpendicular to the longitudinal axis, and at least one particle motivating force directionally interacting with at least one recurrent circulating fluid flow generally aligned with the longitudinal axis within the fluid containing cell.Type: ApplicationFiled: December 9, 2010Publication date: March 31, 2011Applicant: The Regents of University of CaliforniaInventors: Igor Mezic, Frederic Bottausci, Idan Tuval
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Publication number: 20100316531Abstract: A microfluidic device comprising first and second substrates respectively including first and second hydrophobic layers based on polysiloxane, said hydrophobic layers each comprising an assembly area. The substrates are assembled with each other at said assembly areas by means of an adhesive based on silicone.Type: ApplicationFiled: June 10, 2010Publication date: December 16, 2010Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Cyril Delattre, Frédéric Bottausci
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Publication number: 20100018861Abstract: An apparatus and method to achieve manipulation of particles and/or solutions through the induction of electromagnetic fields inside liquid contained inside vessels are disclosed. A “vessel” denotes specifically either a microtitter plate (microplate or well-plate, 1536, 3456 or any other format) well or hybridization solution placed on microarrays for hybridization experiment purposes or more generally any volume containing liquid solution. The manipulation is performed by bringing the active part of the device into contact with the fluidic solution, wherein electromagnetic fields and/or induced fluid flow are used to perform specific manipulations including transport, separation, concentration, mixing, reaction and electroporation. The invention can be used to enhance processing in a number of standard assays and protocols, including the Polymerase Chain Reaction, kinase-based assays, ELISA assays and electroporation.Type: ApplicationFiled: March 26, 2008Publication date: January 28, 2010Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Igor Mezic, Frederic Bottausci
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Publication number: 20090038938Abstract: A software-driven device named the Microfluidic Central Processing Unit (?fCPU). The device is a chamber encompassing a contiguous physical volume equipped with actuators (electrodes, pressure membranes or other) capable of inducing physical forces on liquids, gases and particles contained in it, for the purpose of performing at least the 5 basic microfluidics operations: mixing, concentration, separation, transport and reaction within one integrated chamber. The device can have one volume where all of the operations are performed or can be spatially divided into several “processing areas” between which there are transport routes enabled by the software-regulated actuation. A device that contains more than one ?fCPU employed in parallel or in series or both. A device that is composed of one or more than one ?fCPU's and where fluids and particles are transported using a central pump together with integrated micropumps.Type: ApplicationFiled: May 9, 2008Publication date: February 12, 2009Applicant: The Regents of The University of CaliforniaInventors: Igor Mezic, Frederic Bottausci
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Publication number: 20090034359Abstract: Microscale or nanoscale apparatus for stopped-flow, quenched flow or continuous flow reaction apparatus where fluids or gases are mixed in a device composed of parallel or serial assembly of the basic fluid-containing cell having a longitudinal axis, a cross-sectional area generally perpendicular to the longitudinal axis, and at least one connected crossing cell having a longitudinal axis, a cross-sectional area generally perpendicular to said longitudinal axis and a fluid motivating force interacting transversally with the fluids flow.Type: ApplicationFiled: April 4, 2008Publication date: February 5, 2009Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Caroline Cardonne, Frederic Bottausci, Carl D. Meinhart, Igor Mezic
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Publication number: 20090032398Abstract: An apparatus, a method and a process to achieve manipulation of particles and/or solutions through the use of electrokinetic properties are disclosed. The manipulation is performed using a disposable device positioned on top of a stage for purposes of powering the electrodes. The fluidic solution is brought into contact with the active part of the device and then manipulated.Type: ApplicationFiled: May 14, 2008Publication date: February 5, 2009Applicant: The Regents of the University of CaliforniaInventors: Igor Mezic, Frederic Bottausci, Jason S. Spievak, Peter J. Strand
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Publication number: 20070175755Abstract: Particles are separated, concentrated, or mixed within a fluid by means of a fluid-containing cell having a longitudinal axis, a cross-sectional area generally perpendicular to the longitudinal axis, and at least one particle motivating force directionally interacting with at least one recurrent circulating fluid flow generally aligned with the longitudinal axis within the fluid containing cell.Type: ApplicationFiled: November 17, 2006Publication date: August 2, 2007Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Igor Mezic, Frederic Bottausci, Idan Tuval