Patents by Inventor Frederic Bottausci

Frederic Bottausci has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11692960
    Abstract: An electrochemical measurement cartridge includes a container including a first analysis chamber for receiving a fluid to be analyzed and a second calibration chamber for receiving a calibration fluid; an electrochemical measurement sensor including at least one work electrode and one reference electrode; a container supporting the sensor and a cover arranged mobile relative to one another to confer on the cartridge at least two separate operating configurations, a first configuration in which the sensor is communicating with the first analysis chamber and a second configuration in which the sensor is communicating with the second calibration chamber; sealing between the chambers of the container and the cover; and a drive member for providing a relative movement of the container relative to the cover.
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: July 4, 2023
    Assignee: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Eric Gouze, Frederic Bottausci, Pascal Mailley, Olivier Fuchs
  • Patent number: 11426106
    Abstract: A medical drain sensor is provided located in a region of a drain tube which has turbulent or re-circulatory exudate flow. Means are provided in some embodiments to promote or enhance such flow.
    Type: Grant
    Filed: May 1, 2018
    Date of Patent: August 30, 2022
    Assignees: Sofradim Production, CEA (Commissariat A L'energie Atomique Et Aux Energies Alternatives)
    Inventors: Yves Bayon, Dagmar Guyader, Maxime Gougis, Mélanie Alias, Séverine Vignoud, Frederic Bottausci, Pascal Mailley
  • Publication number: 20220168232
    Abstract: A capsule including alginate encapsulating: insulin-secreting cells, a RGD-alginate, mesenchymal stem cells, extracellular matrix, the process for the preparation thereof and the use thereof for treating diabetes.
    Type: Application
    Filed: March 27, 2020
    Publication date: June 2, 2022
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE GRENOBLE ALPES, ETABLISSEMENT FRANCAIS DU SANG, WAKE FOREST UNIVERSITY HEALTH SCIENCES
    Inventors: Sandrine LABLANCHE, Pierre-Yves BENHAMOU, Emily TUBBS, Anaïck MOISAN, Harald EGELHOFER, Virginie PERSOONS, Florence RIVERA, Frédéric BOTTAUSCI, Maxime PIERRON, Giuseppe ORLANDO, Riccardo TAMBURRINI
  • Publication number: 20210178131
    Abstract: In a surgical drain system formed with two or more branches, exudate flow from a patient's wound is directed between two branches with the respective filling and emptying times determined in order to identify the presence of a blockage in the drain.
    Type: Application
    Filed: February 19, 2021
    Publication date: June 17, 2021
    Inventors: Yves Bayon, Dagmar Guyader, Maxime Gougis, Severine Vignoud, Frederic Bottausci, Pascal Mailley
  • Patent number: 10983093
    Abstract: A chemical sensor including at least one resonant detection structure, the detection structure including at least one layer based on a porous material, the pores of which are covered with at least one functionalization layer that can adsorb or absorb at least one chemical species.
    Type: Grant
    Filed: July 25, 2017
    Date of Patent: April 20, 2021
    Assignee: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Thierry Claret, Frederic Bottausci, Guy-Michel Parat, Severine Vignoud
  • Patent number: 10953207
    Abstract: In a surgical drain system formed with two or more branches, exudate flow from a patient's wound is directed between two branches with the respective filling and emptying times determined in order to identify the presence of a blockage in the drain.
    Type: Grant
    Filed: May 1, 2018
    Date of Patent: March 23, 2021
    Assignees: Sofradim, CEA (Commissariat A L'energie Atomique Et Aux Energies Alternatives)
    Inventors: Yves Bayon, Dagmar Guyader, Maxime Gougis, Séverine Vignoud, Frederic Bottausci, Pascal Mailley
  • Publication number: 20200173950
    Abstract: An electrochemical measurement cartridge includes a container including a first analysis chamber for receiving a fluid to be analyzed and a second calibration chamber for receiving a calibration fluid; an electrochemical measurement sensor including at least one work electrode and one reference electrode; a container supporting the sensor and a cover arranged mobile relative to one another to confer on the cartridge at least two separate operating configurations, a first configuration in which the sensor is communicating with the first analysis chamber and a second configuration in which the sensor is communicating with the second calibration chamber; sealing between the chambers of the container and the cover; and a drive member for providing a relative movement of the container relative to the cover
    Type: Application
    Filed: May 24, 2018
    Publication date: June 4, 2020
    Applicant: Commissariat à l 'énergie atomique et aux énergies alternatives
    Inventors: Eric GOUZE, Frederic BOTTAUSCI, Pascal MAILLEY, Olivier FUCHS
  • Publication number: 20180338714
    Abstract: A medical drain sensor is provided located in a region of a drain tube which has turbulent or re-circulatory exudate flow. Means are provided in some embodiments to promote or enhance such flow.
    Type: Application
    Filed: May 1, 2018
    Publication date: November 29, 2018
    Inventors: Yves Bayon, Dagmar Guyader, Maxime Gougis, Mélanie Alias, Séverine Vignoud, Frederic Bottausci, Pascal Mailley
  • Publication number: 20180339140
    Abstract: In a surgical drain system formed with two or more branches, exudate flow from a patient's wound is directed between two branches with the respective filling and emptying times determined in order to identify the presence of a blockage in the drain.
    Type: Application
    Filed: May 1, 2018
    Publication date: November 29, 2018
    Inventors: Yves Bayon, Dagmar Guyader, Maxime Gougis, Séverine Vignoud, Frederic Bottausci, Pascal Mailley
  • Publication number: 20140174992
    Abstract: Particles are separated, concentrated, or mixed within a fluid by means of a fluid-containing cell having a longitudinal axis, a cross-sectional area generally perpendicular to the longitudinal axis, and at least one particle motivating force directionally interacting with at least one recurrent circulating fluid flow generally aligned with the longitudinal axis within the fluid containing cell.
    Type: Application
    Filed: August 20, 2013
    Publication date: June 26, 2014
    Applicant: The Regents of the University of California
    Inventors: Igor Mezic, Frederic Bottausci, Idan Tuval
  • Publication number: 20120298512
    Abstract: An apparatus, a method and a process to achieve manipulation of particles and/or solutions through the use of electrokinetic properties are disclosed. The manipulation is performed using a disposable device positioned on top of a stage for purposes of powering the electrodes. The fluidic solution is brought into contact with the active part of the device and then manipulated.
    Type: Application
    Filed: July 30, 2012
    Publication date: November 29, 2012
    Applicant: The Regents of the University of California
    Inventors: Igor Mezic, Frederic Bottausci, Jason S. Spievak, Peter J. Strand
  • Patent number: 8246802
    Abstract: An apparatus, a method and a process to achieve manipulation of particles and/or solutions through the use of electrokinetic properties are disclosed. The manipulation is performed using a disposable device positioned on top of a stage for purposes of powering the electrodes. The fluidic solution is brought into contact with the active part of the device and then manipulated.
    Type: Grant
    Filed: May 14, 2008
    Date of Patent: August 21, 2012
    Assignee: The Regents of the University of California
    Inventors: Igor Mezic, Frederic Bottausci, Jason S. Spievak, Peter J. Strand
  • Patent number: 8182669
    Abstract: Particles are separated, concentrated, or mixed within a fluid by means of a fluid-containing cell having a longitudinal axis, a cross-sectional area generally perpendicular to the longitudinal axis, and at least one particle motivating force directionally interacting with at least one recurrent circulating fluid flow generally aligned with the longitudinal axis within the fluid containing cell.
    Type: Grant
    Filed: November 17, 2006
    Date of Patent: May 22, 2012
    Assignee: The Regents of the University of California
    Inventors: Igor Mezic, Frederic Bottausci, Idan Tuval
  • Publication number: 20110073531
    Abstract: Particles are separated, concentrated, or mixed within a fluid by means of a fluid-containing cell having a longitudinal axis, a cross-sectional area generally perpendicular to the longitudinal axis, and at least one particle motivating force directionally interacting with at least one recurrent circulating fluid flow generally aligned with the longitudinal axis within the fluid containing cell.
    Type: Application
    Filed: December 9, 2010
    Publication date: March 31, 2011
    Applicant: The Regents of University of California
    Inventors: Igor Mezic, Frederic Bottausci, Idan Tuval
  • Publication number: 20100316531
    Abstract: A microfluidic device comprising first and second substrates respectively including first and second hydrophobic layers based on polysiloxane, said hydrophobic layers each comprising an assembly area. The substrates are assembled with each other at said assembly areas by means of an adhesive based on silicone.
    Type: Application
    Filed: June 10, 2010
    Publication date: December 16, 2010
    Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Cyril Delattre, Frédéric Bottausci
  • Publication number: 20100018861
    Abstract: An apparatus and method to achieve manipulation of particles and/or solutions through the induction of electromagnetic fields inside liquid contained inside vessels are disclosed. A “vessel” denotes specifically either a microtitter plate (microplate or well-plate, 1536, 3456 or any other format) well or hybridization solution placed on microarrays for hybridization experiment purposes or more generally any volume containing liquid solution. The manipulation is performed by bringing the active part of the device into contact with the fluidic solution, wherein electromagnetic fields and/or induced fluid flow are used to perform specific manipulations including transport, separation, concentration, mixing, reaction and electroporation. The invention can be used to enhance processing in a number of standard assays and protocols, including the Polymerase Chain Reaction, kinase-based assays, ELISA assays and electroporation.
    Type: Application
    Filed: March 26, 2008
    Publication date: January 28, 2010
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Igor Mezic, Frederic Bottausci
  • Publication number: 20090038938
    Abstract: A software-driven device named the Microfluidic Central Processing Unit (?fCPU). The device is a chamber encompassing a contiguous physical volume equipped with actuators (electrodes, pressure membranes or other) capable of inducing physical forces on liquids, gases and particles contained in it, for the purpose of performing at least the 5 basic microfluidics operations: mixing, concentration, separation, transport and reaction within one integrated chamber. The device can have one volume where all of the operations are performed or can be spatially divided into several “processing areas” between which there are transport routes enabled by the software-regulated actuation. A device that contains more than one ?fCPU employed in parallel or in series or both. A device that is composed of one or more than one ?fCPU's and where fluids and particles are transported using a central pump together with integrated micropumps.
    Type: Application
    Filed: May 9, 2008
    Publication date: February 12, 2009
    Applicant: The Regents of The University of California
    Inventors: Igor Mezic, Frederic Bottausci
  • Publication number: 20090034359
    Abstract: Microscale or nanoscale apparatus for stopped-flow, quenched flow or continuous flow reaction apparatus where fluids or gases are mixed in a device composed of parallel or serial assembly of the basic fluid-containing cell having a longitudinal axis, a cross-sectional area generally perpendicular to the longitudinal axis, and at least one connected crossing cell having a longitudinal axis, a cross-sectional area generally perpendicular to said longitudinal axis and a fluid motivating force interacting transversally with the fluids flow.
    Type: Application
    Filed: April 4, 2008
    Publication date: February 5, 2009
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Caroline Cardonne, Frederic Bottausci, Carl D. Meinhart, Igor Mezic
  • Publication number: 20090032398
    Abstract: An apparatus, a method and a process to achieve manipulation of particles and/or solutions through the use of electrokinetic properties are disclosed. The manipulation is performed using a disposable device positioned on top of a stage for purposes of powering the electrodes. The fluidic solution is brought into contact with the active part of the device and then manipulated.
    Type: Application
    Filed: May 14, 2008
    Publication date: February 5, 2009
    Applicant: The Regents of the University of California
    Inventors: Igor Mezic, Frederic Bottausci, Jason S. Spievak, Peter J. Strand
  • Publication number: 20070175755
    Abstract: Particles are separated, concentrated, or mixed within a fluid by means of a fluid-containing cell having a longitudinal axis, a cross-sectional area generally perpendicular to the longitudinal axis, and at least one particle motivating force directionally interacting with at least one recurrent circulating fluid flow generally aligned with the longitudinal axis within the fluid containing cell.
    Type: Application
    Filed: November 17, 2006
    Publication date: August 2, 2007
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Igor Mezic, Frederic Bottausci, Idan Tuval