Patents by Inventor Frederic Colland

Frederic Colland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9546150
    Abstract: The present invention relates to quinazolin-4-one compounds of formula (I?), their process of preparation and uses thereof. These compounds are useful as selective and reversible inhibitors of ubiquitin specific proteases, particularly USP7, for treating e.g. cancer, neurodegenerative diseases, inflammatory disorders and viral infections.
    Type: Grant
    Filed: August 29, 2012
    Date of Patent: January 17, 2017
    Assignee: HYBRIGENICS SA
    Inventors: Frédéric Colland, Marie-Edith Gourdel
  • Patent number: 9328093
    Abstract: The present invention concerns the discovery of new selective inhibitors of ubiquitin specific proteases, their process of preparation and their therapeutic use.
    Type: Grant
    Filed: September 17, 2014
    Date of Patent: May 3, 2016
    Assignee: HYBRIGENICS SA
    Inventors: Roman Lopez, Frederic Colland
  • Publication number: 20150072973
    Abstract: The present invention concerns the discovery of new selective inhibitors of ubiquitin specific proteases, their process of preparation and their therapeutic use.
    Type: Application
    Filed: September 17, 2014
    Publication date: March 12, 2015
    Inventors: Roman Lopez, Frederic Colland
  • Publication number: 20140371247
    Abstract: The present invention relates to quinazolin-4-one compounds of formula (I?), their process of preparation and uses thereof. These compounds are useful as selective and reversible inhibitors of ubiquitin specific proteases, particularly USP7, for treating e.g. cancer, neurodegenerative diseases, inflammatory disorders and viral infections.
    Type: Application
    Filed: August 29, 2012
    Publication date: December 18, 2014
    Applicant: HYBRIGENICS SA
    Inventors: Frédéric Colland, Marie-Edith Gourdel
  • Patent number: 8648076
    Abstract: The present invention concerns new compounds of formula (I), their process of preparation and their therapeutic use.
    Type: Grant
    Filed: July 26, 2006
    Date of Patent: February 11, 2014
    Assignee: Hybrigenics SA
    Inventors: Philippe Guedat, Guillaume Boissy, Catherine Borg-Capra, Frédéric Colland, Laurent Daviet, Etienne Formstecher, Xavier Jacq, Jean-Christophe Rain, Rémi Delansorne, Stefania Vallese, Matteo Colombo
  • Publication number: 20130023521
    Abstract: The present invention concerns the discovery of new selective inhibitors of ubiquitin specific proteases, their process of preparation and their therapeutic use.
    Type: Application
    Filed: January 17, 2011
    Publication date: January 24, 2013
    Applicant: HYBRIGENICS SA
    Inventors: Roman Lopez, Frederic Colland
  • Publication number: 20110237644
    Abstract: Use of a polypeptide selected from the group consisting of USP13, USP26, USP38, USP42 or USP46 as a screening tool for an agent for treating cancer.
    Type: Application
    Filed: October 29, 2009
    Publication date: September 29, 2011
    Applicants: Les Laboratoires Servier, Hybrigenics
    Inventors: Olivier Geneste, John Hickman, Frédéric Colland, Laurent Daviet
  • Publication number: 20110177105
    Abstract: The present invention concerns the discovery of new selective inhibitors of ubiquitin specific proteases, their process of preparation and their therapeutic use.
    Type: Application
    Filed: August 13, 2010
    Publication date: July 21, 2011
    Inventors: Roman Lopez, Frédéric Colland
  • Patent number: 7875613
    Abstract: The present invention concerns new compounds of formula (I), their process of preparation and their therapeutic use wherein R3, R4, R5, R6, Y, Het1, T, U, V, W, X, Ru, Rv and Rw are as defined in claim 1.
    Type: Grant
    Filed: October 30, 2006
    Date of Patent: January 25, 2011
    Assignee: Hybrigenics SA
    Inventors: Philippe Guedat, Xavier Jacq, Frédéric Colland, Laurent Daviet, Etienne Formstecher, Jean-Christophe Rain, Matteo Colombo
  • Publication number: 20100048575
    Abstract: The present invention concerns new compounds of formula (I), their process of preparation and their therapeutic use: Formula (I) wherein R3, R4, R5, R6, Y, Het1, T, U, V, W, X, Ru, Rv and Rw are as defined in claim 1
    Type: Application
    Filed: October 25, 2007
    Publication date: February 25, 2010
    Inventors: Philippe Guedat, Xavier Jacq, Frédéric Colland, Laurent Daviet, Etienne Formstecher, Jean-Christophe Rain, Matteo Colombo
  • Publication number: 20090215786
    Abstract: The present invention concerns new compounds of formula (I), their process of preparation and their therapeutic use.
    Type: Application
    Filed: July 26, 2006
    Publication date: August 27, 2009
    Inventors: Philippe Guedat, Guillaume Boissy, Catherine Borg-Capra, Frederic Colland, Laurent Daviet, Etienne Formstecher, Xavier Jacq, Jean-Christophe Rain, Remi Delansorne, Stefania Vallese, Matteo Colombo
  • Publication number: 20090181972
    Abstract: The present invention concerns new compounds of formula (I), their process of preparation and their therapeutic use.
    Type: Application
    Filed: December 5, 2006
    Publication date: July 16, 2009
    Inventors: Philippe Guedat, Guillaune Boissy, Catherine Borg-Capra, Frederic Colland, Laurent Daviet, Etienne Formstecher, Xavier Jacq, Jean-Christophe Rain, Remi Delansorne, Ilaria Peretto, Stefano Vignando
  • Patent number: 7462615
    Abstract: The present invention concerns new compounds of formula (I), their process of preparation and their therapeutic use.
    Type: Grant
    Filed: December 8, 2005
    Date of Patent: December 9, 2008
    Assignee: Hybrigenics SA
    Inventors: Philippe Guedat, Guillaume Boissy, Catherine Borg-Capra, Frédéric Colland, Laurent Daviet, Etienne Formstecher, Xavier Jacq, Jean-Christophe Rain, Rémi Delansorne, Ilaria Peretto, Stefano Vignando
  • Publication number: 20080103149
    Abstract: The present invention concerns new compounds of formula (I), their process of preparation and their therapeutic use wherein R3, R4, R5, R6, Y, Het1, T, U, V, W, X, Ru, Rv and Rw are as defined in claim 1
    Type: Application
    Filed: October 30, 2006
    Publication date: May 1, 2008
    Inventors: Philippe GUEDAT, Xavier Jacq, Frederic Colland, Laurent Daviet, Etienne Formstecher, Jean-Christophe Rain, Matteo Colombo
  • Publication number: 20070135439
    Abstract: The present invention concerns new compounds of formula (I), their process of preparation and their therapeutic use.
    Type: Application
    Filed: December 8, 2005
    Publication date: June 14, 2007
    Inventors: Philippe Guedat, Guillaume Boissy, Catherine Borg-Capra, Frederic Colland, Laurent Daviet, Etienne Formstecher, Xavier Jacq, Jean-Christophe Rain, Remi Delansorne, IIaria Peretto, Stefano Vignando
  • Publication number: 20070032499
    Abstract: The present invention concerns new compounds of formula (I), their process of preparation and their therapeutic use.
    Type: Application
    Filed: August 5, 2005
    Publication date: February 8, 2007
    Inventors: Philippe Guedat, Guillaume Boissy, Catherine Borg-Capra, Frederic Colland, Laurent Daviet, Etienne Formstecher, Xavier Jacq, Jean-Christophe Rain, Rerni Delansorne, Stefania Vallese, Matteo Colombo
  • Publication number: 20060165699
    Abstract: The present invention relates to the use of inhibitors of the expressed proteins of TCF target genes whose expression is regulated by TCF/?-catenin complexes for the preparation of a therapeutical composition for the treatment of cancers in which TCF/?-catenin signalling is deregulated. Such inhibitors can be antibodies, small molecules, antisense RNA and dsRNA for use in RNAi. The invention also relates to these inhibitors per se.
    Type: Application
    Filed: July 8, 2003
    Publication date: July 27, 2006
    Inventors: Frederic Colland, Nicholas Barker, Johannes Clevers, Eduard Gomez, Marcus Lambertus, Elena Suils
  • Publication number: 20020192796
    Abstract: Disclosed are polypeptides named HP1122, Cj1464 and PA3351 which are the anti-&sgr;28 factor of Helicobacter pylori, Campylobacter jejuni and Pseudomonas aeruginosa, respectively and fragments and variants thereof. Also disclosed is a polypeptide named SID1122 which is the domain of Helicobacter pylori's HP1122 polypeptide involved in a specific interaction with Helicobacter pylori &sgr;28 (HP1032) and which has an anti-&sgr;28 factor activity.
    Type: Application
    Filed: January 31, 2002
    Publication date: December 19, 2002
    Inventors: Pierre Legrain, Frederic Colland, Jean-Christophe Rain, Agnes Labigne, Hilde De Reuse