Patents by Inventor Frederic Galli

Frederic Galli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-(Oxadiazol-3-yl)-1,4-diazabicyclo[3.2.2]-nonane derivatives, preparation and therapeutic use thereof
    Patent number: 7022697
    Abstract: The invention relates to compounds of the Formula I, to pharmaceutical compositions comprising them, and to the method of use thereof in the treatment or prevention of disorders linked to a dysfunction of the nicotinic receptors.
    Type: Grant
    Filed: November 21, 2002
    Date of Patent: April 4, 2006
    Assignee: Sanofi-aventis
    Inventors: Frédéric Galli, Odile Leclerc, Alistair Lochead
  • 4-(2 phenylthiazol-5-yl)-1, 4-diazabicyclo-[3.2.2]nonane derivatives, preparation and therapeutic use thereof
    Patent number: 7001902
    Abstract: Compound corresponding to the general formula (I) in which R1, R2, R3, R4 and R5 each represent a hydrogen or halogen atom or a nitro, amino, trifluoromethyl, trifluoroalkoxy, cyano, hydroxyl, (C1–C6)alkyl or (C1–C6)alkoxy group and R6 represents a (C1–C6)alkyl group. Therapeutic application.
    Type: Grant
    Filed: May 29, 2001
    Date of Patent: February 21, 2006
    Assignee: sanotl-aventis
    Inventors: Thierry Gallet, Frédéric Galli, Odile Leclerc, Alistair Lochead
  • 4-(1,3,4-thiadiazol-2-yl)-1,4-diazabicyclo-[3.2.2]nonane derivatives, preparation and therapeutic use thereof
    Patent number: 6998399
    Abstract: The invention relates to compounds of the Formula I, to pharmaceutical compositions comprising them, and to the method of use thereof in the treatment or prevention of disorders associated with a dysfunction of the nicotinic receptors.
    Type: Grant
    Filed: November 21, 2002
    Date of Patent: February 14, 2006
    Assignee: sanofi-aventis
    Inventors: Frédéric Galli, Odile Leclerc, Alistair Lochead
  • 1,4-Diazabicyclo[3.2.2]nonanecarboxamide derivatives, preparation and therapeutic use thereof
    Publication number: 20050182062
    Abstract: The present invention discloses and claims compounds of general formula in which X represents a nitrogen atom or a group of formula C—R2, P represents a group of formula C—R3, Q represents a group of formula C—R4, R represents a group of formula C—R5, W represents a group of formula C—R6, or one of the symbols P, Q, R and W represents a nitrogen atom, R1 represents a hydrogen atom or an alkyl group, R2 represents a hydrogen atom or an alkyl group, R3, R4, R5 and R6 each represent a hydrogen or halogen atom, or an alkyl, alkoxy, nitro, amino, trifluoromethyl, cyano or amino group or other functional groups. The compounds of the invention are useful in a variety of therapeutic applications.
    Type: Application
    Filed: April 4, 2005
    Publication date: August 18, 2005
    Applicant: SANOFI-AVENTIS
    Inventors: Frederic Galli, Patrick Lardenois, Odile Leclerc, Alistair Lochead
  • Pyridopyranoazepine derivatives, their preparation and their therapeutic application
    Patent number: 6908927
    Abstract: The invention relates to pyridopyranoazepine derivatives, to pharmaceutical compositions containing them, to process for preparing them, and to the method of use thereof in the treatment or prevention of disorders associated with a dysfunction of the nicotine receptors.
    Type: Grant
    Filed: February 6, 2003
    Date of Patent: June 21, 2005
    Assignee: Sanofi-Synthelabo
    Inventors: Frédéric Galli, Samir Jegham, Alistair Lochead, Axelle Samson
  • Derivatives of 5-(pyridin-3-yl)-1-azabicyclo[3.2.1] octane, the preparation thereof and the application of same in therapeutics
    Publication number: 20050020568
    Abstract: Compounds complying with the general formula (I) in which R either represents a halogen atom or a phenyl group substituted by one or more groups chosen from halogen atoms and (C1-C6)alkyl, (C1-C6)alkoxy, nitro, amino, trifluoromethyl, cyano, hydroxy, acetyl or methylenedioxy groups, or represents a pyridinyl group, a thienyl group, an indolyl group, or a pyrimidinyl group optionally substituted by one or more (C1-C6)alkoxy groups, where, of the two carbon-carbon bonds represented by , one is single and the other may be single or double. Therapeutic application.
    Type: Application
    Filed: January 3, 2003
    Publication date: January 27, 2005
    Inventors: Frederic Galli, Odile Leclerc, Alistair Lochead, Alain Nedelec
  • 4-(1,3,4,-thiadiazol-2-yl)-1,4-diazabicyclo-[3.2.2]nonane derivatives, preparation and therapeutic use thereof
    Publication number: 20050020599
    Abstract: The invention relates to compounds of the Formula I, to pharmaceutical compositions comprising them, and to the method of use thereof in the treatment or prevention of disorders associated with a dysfunction of the nicotinic receptors.
    Type: Application
    Filed: November 21, 2002
    Publication date: January 27, 2005
    Inventors: Frederic Galli, Odile Leclerc, Alistair Lochead
  • 1,4-diazabicyclo[3.2.2]nonane-phenylisoxazole derivatives, their preparation and their application in therapeutics
    Patent number: 6844337
    Abstract: Compounds corresponding to general formula (I) in which R1, R2, R3, R4 and R5 each represent, independently of one another, a hydrogen or halogen atom or a nitro, amino, trifluoromethyl, trifluoromethoxy, cyano, hydroxy, (C1-C6)alkyl, (C1-C6)alkoxy or phenyl group, it also being possible for two of these substituents in adjacent positions together to represent a methylenedioxy group, and R6 represents a hydrogen atom or a (C1-C6)alkyl group. Application in therapeutics.
    Type: Grant
    Filed: May 29, 2001
    Date of Patent: January 18, 2005
    Assignee: Sanofi-Synthelabo
    Inventors: Frédéric Galli, Odile Leclerc, Alistair Lochead
  • 4-(Oxazolopyridin-2-yl)-1,4-diazabicyclo-[3.2.2]nonane derivatives, preparation and therapeutic use thereof
    Publication number: 20050004128
    Abstract: Compound corresponding to the general formula (I) in which R2 represents a chlorine atom, a methyl group or a 3-thienyl group. Therapeutic application.
    Type: Application
    Filed: November 20, 2002
    Publication date: January 6, 2005
    Inventors: Frederic Galli, Odile Leclerc, Alistair Lochead
  • 4-(Oxadiazol-3-yl)-1,4-diazabicyclo[3.2.2]-nonane derivatives, preparation and therapeutic use thereof
    Publication number: 20040266757
    Abstract: The invention relates to compounds of the Formula I, to pharmaceutical compositions comprising them, and to the method of use thereof in the treatment or prevention of disorders linked to a dysfunction of the nicotinic receptors.
    Type: Application
    Filed: May 18, 2004
    Publication date: December 30, 2004
    Inventors: Frederic Galli, Odile Leclerc, Alistair Lochead
  • 4-heteroparyl-1,4-diazabicyclo[3.2.2]nonane, preparation and therapeutic use thereof
    Patent number: 6835730
    Abstract: Compounds of the general formula (I) in which R1, R2, R3 and R4 each represent a hydrogen or halogen atom or a nitro, amino, trifluoromethyl, cyano, hydroxyl, alkyl or alkoxy group, X represents either a nitrogen atom, in which case Z represents a group of the formula C—R5 or a nitrogen atom, or a group of the formula C—R6, in which case Z represents a nitrogen atom, R5 and R6 each represent a hydrogen or halogen atom or a trifluoromethyl, cyano, hydroxyl, (C1-C6)alkyl or (C1-C6)alkoxy group, and R7 represents a hydrogen atom or a (C1-C6)alkyl group. Use in therapy.
    Type: Grant
    Filed: September 24, 2002
    Date of Patent: December 28, 2004
    Assignee: Sanofi-Synthelabo
    Inventors: Frédéric Galli, Samir Jegham, Odile Leclerc, Alistair Lochead, Alain Nedelec
  • 4-(2 phenylthiazol-5-yl)-1, 4-diazabicyclo-[3.2.2]nonane deirvatives, preparation and therapeutic use thereof
    Publication number: 20040029884
    Abstract: Compound corresponding to the general formula (I) 1
    Type: Application
    Filed: November 18, 2002
    Publication date: February 12, 2004
    Inventors: Thierry Gallet, Frederic Galli, Odile Leclerc, Alistair Lochead
  • 2,5,-diazabicyclo[2.2.1]heptane derivatives, their preparation and therapeutic uses
    Patent number: 6635645
    Abstract: The invention relates to 2,5-diazabicyclo[2.2.1]heptane derivatives, to pharmaceutical compositions containing them, and to methods for the treatment or prevention of disorders associated with a dysfunction of the nicotinic receptors utilizing them.
    Type: Grant
    Filed: August 16, 2001
    Date of Patent: October 21, 2003
    Assignee: Sanofi-Synthelabo
    Inventors: Alistair Lochead, Samir Jegham, Alain Nedelec, Jean Jeunesse, Frédéric Galli, Luc Even
  • Pyridopyranoazepine derivatives, their preparation and their therapeutic application
    Publication number: 20030187012
    Abstract: The invention relates to pyridopyranoazepine derivatives, to pharmaceutical compositions containing them, to process for preparing them, and to the method of use thereof in the treatment or prevention of disorders associated with a dysfunction of the nicotine receptors.
    Type: Application
    Filed: February 6, 2003
    Publication date: October 2, 2003
    Inventors: Frederic Galli, Samir Jegham, Alistair Lochead, Axelle Samson
  • 1,4-diazabicyclo[3.2.2]nonabenzoxazole, -benzothiazole and benzimidazole derivatives, preparation and therapeutic use thereof
    Publication number: 20030153574
    Abstract: Compound corresponding to the general formula (I) 1
    Type: Application
    Filed: February 24, 2003
    Publication date: August 14, 2003
    Inventors: Frederic Galli, Alistair Lochead, Axelle Samson
  • 4-Heteroparyl-1,4-diazabicyclo[3.2.2]nonane, preparation and therapeutic use thereof
    Publication number: 20030119840
    Abstract: Compounds of the general formula (I) 1
    Type: Application
    Filed: September 24, 2002
    Publication date: June 26, 2003
    Inventors: Frederic Galli, Samir Jegham, Odile Leclerc, Alistair Lochead, Alain Nedelec
  • 1,4-Diazabicyclo[3.2.2]nonane-phenylisoxazole derivatives, preparation and therapeutic use thereof
    Publication number: 20030114461
    Abstract: Compounds corresponding to general formula (I) 1
    Type: Application
    Filed: November 18, 2002
    Publication date: June 19, 2003
    Inventors: Frederic Galli, Odile Leclerc, Alistair Lochead
  • Pyridopyranoazepine derivatives, their preparation and their therapeutic application
    Patent number: 6538003
    Abstract: The invention relates to pyridopyranoazepine derivatives, to pharmaceutical compositions containing them, to processes for preparing them, and to the method of use thereof in the treatment or prevention of disorders associated with a dysfunction of the nicotine receptors.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: March 25, 2003
    Assignee: Sanofi-Synthelabo
    Inventors: Frédéric Galli, Samir Jegham, Alistair Lochead, Axelle Samson
  • 1,4-diazabicylo[3,2,2]nonane derivatives, their preparation and their therapeutic application
    Patent number: 6407095
    Abstract: The invention relates to 1,4-diazabicyclo[3.2.2]nonane derivatives, to pharmaceutical compositions containing them, and to methods for the treatment or prevention of disorders associated with a dysfunction of the nicotinic receptors utilizing them.
    Type: Grant
    Filed: July 16, 2001
    Date of Patent: June 18, 2002
    Assignee: Sanofi-Synthelabo
    Inventors: Alistair Lochead, Samir Jegham, Alain Nedelec, Frédéric Galli, Jean Jeunesse, Luc Even
  • 5-aryl-3-(8-azabicyclo[3.2.1]oct-3-yl)-1,3,4-oxadiazol-2(3H)-one derivatives as 5-ht4 receptor ligands
    Patent number: 6255319
    Abstract: Compound of general formula (I) in which R1 represents an alkyl or cycloalkylmethyl group, X1 represents a hydrogen or halogen atom or an alkoxy group, or alternatively OR1 and X1 together represent an —OCH2O—, —O(CH2)2—, —O(CH2)3—, —O(CH2)2O— or —(CH2)3O— group, X2 represents a hydrogen atom or an amino group, X3 represents a hydrogen or halogen atom, and R2 represents a hydrogen atom, an optionally substituted alkyl group, an optionally substituted phenylalkyl group or a group —(CH2)nCO—Z in which n represents a number from 1 to 6 and Z represents a 1-piperidyl group. Therapeutic application.
    Type: Grant
    Filed: October 15, 1999
    Date of Patent: July 3, 2001
    Assignee: Sanofi-Synthelabo
    Inventors: Samir Jegham, Alistair Lochead, Frédéric Galli, Alain Nedelec, Axelle Samson, Thierry Gallet