Patents by Inventor Frederic Leduc

Frederic Leduc has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240115954
    Abstract: Two dimensional images are converted to a 3D neural radiance field (NeRF), which is modified based on text personalized to a player and input to resemble the accoutrement for a character demanded by the text. A model scores how well an image matches a line of text to produce a final 3D NeRF, which may be converted to a polygonal mesh and imported into a computer simulation such as a computer game.
    Type: Application
    Filed: October 5, 2022
    Publication date: April 11, 2024
    Inventors: Joseph Logan Olson, MATHIEU Leduc, Frederic Masson
  • Publication number: 20210213118
    Abstract: Antibodies and antigen-binding fragments thereof that specifically recognize Neurotensin receptor type 1 (NTSR1) are described. These anti-NTSR1 antibodies and antigen-binding fragments thereof, such as single-chain Fv (scFv), are able to inhibit neurotensin-mediated activation of NTSR1 in normal and tumor cells. Methods and uses of antibodies and antigen-binding fragments thereof for treatment of diseases or conditions associated with NTSR1 activity, such as NTSR1-positive cancers or certain metabolic diseases, are also described. Cyclic peptides mimicking the conformation of the second extracellular loop of NTSR1 and capable of inducing the production of anti-NTSR1 antibodies in animals such as chickens are also described.
    Type: Application
    Filed: August 30, 2019
    Publication date: July 15, 2021
    Inventors: Eric MARSAULT, Pierre-Luc BOUDREAULT, Hassan TRABOULSI, Philippe SARRET, Marie-Édith NEPVEU-TRAVERSY, Simon GAUDREAU, Frédéric LEDUC, Jeam-François LARRIVÉE, Mathieu ARCAND
  • Patent number: 10907199
    Abstract: The present disclosure provides the quantification of double-strand breaks in DNA molecules using terminal deoxynucleotidyl transferase using a preliminary step of nick gap and repair. This preliminary step comprising contacting the DNA molecules with both a DNA ligase and a DNA polymerase to repair DNA nicks and remove DNA gaps prior to using the terminal deoxynucleotidyl transferase.
    Type: Grant
    Filed: October 23, 2018
    Date of Patent: February 2, 2021
    Inventors: Marie-Chantal Gregoire, Guylain Boissonneault, Frédéric Leduc, Julien Massonneau, Olivier Simard, Chloé Lacombe-Burgoyne
  • Publication number: 20200071364
    Abstract: It is described a Clostridium difficile (C-difficile) toxins A and/or B as a target for therapy, including passive immunotherapy, and particularly prevention of C-difficile intoxication in human or other animals. It is also described a polypeptide comprising a portion of C-difficile toxins A and/or B sequence being an epitope for anti-toxins A and/or B antibody. It is also disclosed a method for generating a neutralizing antibody directed against C-difficile toxins A and/or B. It is also provided a novel formulation that combines key toxins A and/or B epitope antibodies, located in three key domains of toxins A and/or B, for neutralisation of the toxins A and/or B, at any stage of toxins A and/or B intoxication related to C-difficile infection. The novel formulation of toxins A and/or B epitope antibodies are useful in immunotherapy, for therapeutic and/or prophylactic mediation of C-difficile intoxication.
    Type: Application
    Filed: November 20, 2019
    Publication date: March 5, 2020
    Inventors: Simon Gaudreau, Martin Cloutier, Louis-Charles Fortier, Frederic Leduc, Maxime Tremblay, Steeve Veronneau, Djorjde Gbric, Jean-Francois Larrivee
  • Patent number: 10533036
    Abstract: It is described a Clostridium difficile (C-difficile) toxins A and/or B as a target for therapy, including passive immunotherapy, and particularly prevention of C-difficile intoxication in human or other animals. It is also described a polypeptide comprising a portion of C-difficile toxins A and/or B sequence being an epitope for anti-toxins A and/or B antibody. It is also disclosed a method for generating a neutralizing antibody directed against C-difficile toxins A and/or B. It is also provided a novel formulation that combines key toxins A and/or B epitope antibodies, located in three key domains of toxins A and/or B, for neutralizing toxins A and/or B, at any stage of toxins A and/or B intoxication related to C-difficile infection. The novel formulation of toxins A and/or B epitope antibodies are useful in immunotherapy, for therapeutic and/or prophylactic mediation of C-difficile intoxication.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: January 14, 2020
    Assignee: IMMUNE BIOSOLUTIONS INC
    Inventors: Simon Gaudreau, Martin Cloutier, Louis-Charles Fortier, Frederic Leduc, Maxime Tremblay, Steeve Veronneau, Djorjde Gbric, Jean-Francois Larrivee
  • Publication number: 20190161792
    Abstract: The present disclosure provides the quantification of double-strand breaks in DNA molecules using terminal deoxynucleotidyl transferase using a preliminary step of nick gap and repair. This preliminary step comprising contacting the DNA molecules with both a DNA ligase and a DNA polymerase to repair DNA nicks and remove DNA gaps prior to using the terminal deoxynucleotidyl transferase.
    Type: Application
    Filed: October 23, 2018
    Publication date: May 30, 2019
    Inventors: Marie-Chantal GREGOIRE, Guylain BOISSONNEAULT, Frédéric LEDUC, Julien MASSONNEAU, Olivier SIMARD, Chloé LACOMBE-BURGOYNE
  • Publication number: 20180022784
    Abstract: It is described a Clostridium difficile (C-difficile) toxins A and/or B as a target for therapy, including passive immunotherapy, and particularly prevention of C-difficile intoxication in human or other animals. It is also described a polypeptide comprising a portion of C-difficile toxins A and/or B sequence being an epitope for anti-toxins A and/or B antibody. It disclosed a method for generating a neutralizing antibody directed against C-difficile toxins A and/or B. It is also provided a novel formulation that combines key toxins A and/or B epitope antibodies, located in three key domains of toxins A and/or B, for neutralisation of the toxins A and/or B, at any stage of toxins A and/or B intoxication related to C-difficile infection. The novel formulation of toxins A and/or B epitope antibodies are useful in immunotherapy, for 10 therapeutic and/or prophylactic mediation of C-difficile intoxication.
    Type: Application
    Filed: February 19, 2016
    Publication date: January 25, 2018
    Inventors: Simon Gaudreau, Martin Cloutier, Louis-Charles Fortier, Frederic Leduc, Maxime Tremblay, Steeve Veronneau, Djorjde Gbric, Jean-Francois Larrivee