Abstract: The invention relates to meganuclease variants which cleave a DNA target sequence from the human Rhodopsin gene (RHO), to vectors encoding such variants, to a cell, an animal or a plant modified by such vectors and to the use of these meganuclease variants and products derived therefrom for genome therapy, ex vivo (gene cell therapy) and genome engineering including therapeutic applications and cell line engineering.

Abstract: The method is to fabricate a microelectronic device with an integrated antenna. This method may include forming at least a first semiconducting layer on a substrate, forming in at least one zone of the first semiconducting layer of a structure to limit the circulation of current in the zone of the first semiconducting layer, forming a plurality of layers on the semiconducting layer and at least one antenna in the plurality of layers, with the antenna being formed opposite the zone. The antenna may be operable at radio frequencies above 10 GHz, and may have an improved emission efficiency.

Abstract: The method is to fabricate a microelectronic device with an integrated antenna. This method may include forming at least a first semiconducting layer on a substrate, forming in at least one zone of the first semiconducting layer of a structure to limit the circulation of current in the zone of the first semiconducting layer, forming a plurality of layers on the semiconducting layer and at least one antenna in the plurality of layers, with the antenna being formed opposite the zone. The antenna may be operable at radio frequencies above 10 GHz, and may have an improved emission efficiency.

Abstract: The invention concerns an intgrated inductor (20), consisting of a flat winding of one or several turns (21, 22, 23) made of a conductive material above a substrate provided with at least a subjacent conductive level wherein is produced, through a contact pick-up strip (12′), at least an intersection of the winding, the width of at least one turn and/or one interval between two turns being reduced in line with said contact pick-up strip.

Abstract: An integrated circuit inductance structure, including a silicon substrate, a planar winding of a conductive track, a resistive layer, not etched under the winding, a dielectric layer between the winding and said resistive layer, and discontinuous conductive sections, individually parallel to a portion of the winding which is the closest and electrically connected to ground and to the more heavily-doped layer.

Abstract: The invention concerns an integrated inductor (20), consisting of a flat winding of one or several turns (21, 22, 23) made of a conductive material above a substrate provided with at least a subjacent conductive level wherein is produced, through a contact pick-up strip (12′), at least an intersection of the winding, the width of at least one turn and/or one interval between two turns being reduced in line with said contact pick-up strip.

Abstract: An inductance structure arranged on a semiconductor substrate, including an inductance and a conductive plane arranged between the inductance and the substrate. The conductive plane is formed of several separate conductive elements, the connection of which is performed by conductive tracks connecting at least one conductive element to a contact point M of the conductive plane. Each of the conductive tracks is arranged so that the resultant of the electromotive forces induced in said conductive track by the inductance is substantially null.

Abstract: An integrated circuit inductance structure, including a silicon substrate, a planar winding of a conductive track, a resistive layer, not etched under the winding, a dielectric layer between the winding and said resistive layer, and discontinuous conductive sections, individually parallel to a portion of the winding which is the closest and electrically connected to ground and to the more heavily-doped layer.

Abstract: An inductance structure arranged on a semiconductor substrate, including an inductance and a conductive plane arranged between the inductance and the substrate. The conductive plane is formed of several separate conductive elements, the connection of which is performed by conductive tracks connecting at least one conductive element to a contact point M of the conductive plane. Each of the conductive tracks is arranged so that the resultant of the electromotive forces induced in said conductive track by the inductance is substantially null.

Abstract: An oscillator includes four identical cells each producing a phase shift of 90 degrees. The output signal from one cell is applied to the input of the next cell, and with the cells looping back to themselves. Each cell includes a current amplifier and a parallel inductance-capacitance resonant circuit configured such that the output current from one cell is a fraction of the capacitive current of the parallel resonant circuit. This causes the 90.degree. phase shift between the input and output currents of each cell.

Abstract: A multiplexer includes 2.sup.q+1 inputs receiving periodic signals, each signal being out of phase with respect to the other signals, and is controlled so as to switch from a present input signal to a next input signal by activation of a switch signal. The next signal has its phase delayed with respect to the present signal by 360.degree./2.sup.q+1. The switching signal is synchronized with an edge of the next input signal.

Abstract: A circuit compensating for the attenuation caused on a line by an LS series type notch filter at frequencies less than the filter cut-off frequency, with such filter connected across said line and a reference voltage, includes a first resistor (R) in series on the line, a series circuit comprising a capacitor (C1) and a second resistor (R1) connected across the line and reference voltage, the capacitor being connected on the side of a first terminal of the first resistor, and an amplifier, the input of which is connected to the connection point of a capacitor and second resistor and the output of which is connected to the second terminal of the first resistor, such amplifier having a transconductance at said lower frequencies capable of ensuring the injection of a current equal to the sum of currents deviated by the series circuit and the filter.

Abstract: The invention relates to differential current amplifiers. In order to obtain amplification of a difference between two currents I1 and I2 with good common mode rejection, the currents I1 and I2 are caused to pass alternately through two equal resistors R1 and R2 and the differential voltage drop across R1 and across R2 is amplified by a voltage amplifier.

Abstract: An oscillator includes four identical cells each producing a phase shift of 90 degrees. The output signal from one cell is applied to the input of the next cell, and with the cells looping back to themselves. Each cell includes a current amplifier and a parallel inductance-capacitance resonant circuit configured such that the output current from one cell is a fraction of the capacitive current of the parallel resonant circuit. This causes the 90° phase shift between the input and output currents of each cell.