Abstract: The present invention relates to an attenuated African Swine Fever (ASF) virus, wherein: ?genes MGF 360-12L, 360-13L, 360-14L, 505-2R, 505-3R are deleted or are interrupted or mutated such that the genes are not transcribed and/or translated, ? ORF of ASFV_G_ACD_00520 is deleted or is interrupted or mutated such that it is not transcribed and/or translated, and ? genes MGF 505-1 R et 505-4R are truncated, compared to the genome of the corresponding unattenuated virus. The present invention also refers to a vaccine comprising the attenuated ASF virus, and its use in preventing African Swine Fever in a subject.

Abstract: The present invention relates to the veterinary field and, more particularly, to shampoo compositions comprising an active ingredient obtained from Ophiopogon japonicus and an amphoteric surfactant, for non-human mammals. The invention also relates to a method for washing the coat of non-human mammals by applying said shampoo compositions to the coat and/or the skin.

Abstract: The present invention relates to novel polyurethanes based on a diisocyanate, a carboxylic acid functionalized diol and an acid-free diol, their use as pharmaceutical excipients for improving gastrointestinal absorption, the respective pharmaceutical dosage forms and methods for making the polyurethanes.

Abstract: A polyisocyanate composition comprising (A) at least one polyisocyanate obtainable by reacting (c) at least one diisocyanate or polyisocyanate, (d) at least one surfactant comprising a mixture of compounds based on the following formulae (I) and (II); in which R1 and R2 independently of one another are alkyl, cycloalkyl or aryl, it being possible for each of the stated radicals to be substituted by aryl, alkyl, aryloxy, alkyloxy, heteroatoms and/or heterocycles, said mixture of compounds of formulae (I) and (II) being characterised in that the molar ratio between compound (II), i.e. the monoester-type compound, and compound (I), i.e. the diester-type compound, is from 5:95 to 95:5, and (c) at least one monofunctional polyalkylene glycol, —and (B) at least one sterically hindered phenol.

Abstract: The present invention relates to a process for the effective removal of residual monomeric aliphatic isocyanate from a reaction mixture comprising aliphatic polyisocyanate comprising (i) providing a reactor containing a scavenger comprising a zeolitic material, wherein the zeolitic material comprises SiO2 and optionally X2O3 in its framework structure, wherein X is a trivalent element; (ii) providing a reaction mixture comprising aliphatic polyisocyanate and monomeric aliphatic isocyanate; (iii) contacting the scavenger in the reactor with the reaction mixture provided in (ii) at a temperature lower than the boiling point of the residual monomeric aliphatic isocyanate for obtaining a product comprising aliphatic polyisocyanate with a reduced monomeric aliphatic isocyanate content, wherein if the zeolitic material comprises X2O3, the zeolitic material has an SiO2 to X2O3 molar ratio higher than 2.8:1, preferably higher than 5:1, more preferably higher than 30:1.

Abstract: A mixture of water-emulsifiable isocyanates is described. The mixture contains (A) at least one polyisocyanate (a), (B) at least one emulsifier obtained by reacting at least one polyisocyanate with at least one polyether alcohol having a molecular weight of less than 400 g/mol, (C) at least one emulsifier obtained by reacting at least one polyisocyanate with at least one polyether alcohol having a molecular weight of greater than 450 g/mol, and (D) optionally at least one emulsifier obtained by reacting a polyisocyanate with at least one compound (d) having at least one hydrophilic, non-isocyanate-reactive group and precisely one isocyanate-reactive group (group D2). The weight ratio of component (B) to component (C) in the mixture is from 30:70 to 70:30, preferably from 40:60 to 60:40.

Abstract: A two-component coating composition comprising at least one water-dispersible polymer mixture (A) which has at least one mercapto-reactive group selected from the group of epoxide and Michael acceptor, and also at least one water-emulsifiable thiol (B) comprising, as formation components, (Ba) at least one compound having at least two mercapto groups, (Bb) at least one compound having at least one mercapto-reactive group and at least one dispersing group, wherein the formation component (Ba) has a Hansch parameter of at least 2.0.

Abstract: A process for producing a water-emulsifiable polyisocyanate formulation, in which, in a first process step, (A) a dispersion-active reaction product (E) is prepared from at least one diisocyanate selected from the group of hexamethylene 1,6-diisocyanate, pentamethylene 1,5-diisocyanate, 4,4?-di(isocyanatocyclohexyl)methane, 1-isocyanato-3,3,5-trimethyl-5-(isocyanatomethyl)cyclohexane, tolylene 2,4- and 2,6-diisocyanate, tetramethylxylylene diisocyanate, p-xylylene diisocyanate, 2,4?- and 4,4?-diisocyanatodiphenylmethane, with at least one mono- or polyhydric polyalkylene ether alcohol having 2 to 4 carbon atoms in the alkylene groups that comprises a polymer chain having at least 8 ethylene oxide units, and the resultant reaction product (E), in a second process step, (B) is mixed with at least one (cyclo)aliphatic polyisocyanate having an average NCO functionality of 2.2 to 5.0, preferably of 2.5 to 4.

Abstract: Mixture comprising a) at least one polyisocyanate, b) at least one reaction product of at least one polyisocyanate b1) with at least one compound b2) having at least one hydrophilic group which is not reactive toward isocyanate (group A) and precisely one group which is reactive toward isocyanate (group B) ?and c) dioxolane.

Abstract: The present invention relates to a polyisocyanate (P) of general formula (I), the method for preparing polysisocyanate (P) of general formula (I) and the use of polyisocyanate (P) of general formula (I) as crosslinking reagent in clearcoats. The method for preparing polyisocyanate (P) of general formula (I) comprises the reaction of a reaction mixture (RM), which comprises at least one cyclic isocyanate of general formula (IIIa), (IIIb), (IIIc), (IIId), (IIIe) and/or (IIIf) and at least one alcohol having at least two hydroxyl groups, to obtain polyisocyanate (P) of general formula (I).

Abstract: A mixture of water-emulsifiable isocyanates is described. The mixture contains (A) at least one polyisocyanate (a), (B) at least one emulsifier obtained by reacting at least one polyisocyanate with at least one polyether alcohol having a molecular weight of less than 400 g/mol, (C) at least one emulsifier obtained by reacting at least one polyisocyanate with at least one polyether alcohol having a molecular weight of greater than 450 g/mol, and (D) optionally at least one emulsifier obtained by reacting a polyisocyanate with at least one compound (d) having at least one hydrophilic, non-isocyanate-reactive group and precisely one isocyanate-reactive group (group D2). The weight ratio of component (B) to component (C) in the mixture is from 30:70 to 70:30, preferably from 40:60 to 60:40.

Abstract: The present invention relates to the use of two-component coating compositions comprising isocyanurates of pentamethylene diisocyanate and NCO group reactive compounds with rapid curing and good chemical resistance at temperatures to 80° C.

Abstract: Binder systems for high-gloss coatings and processes for producing them are provided, where the binder systems are prepared by preparing an aqueous polymer dispersion by radically initiated aqueous emulsion polymerization using defined first and second polymerization stages wherein the weight ratio of the sum of the total amounts of first polymerization stage monomers A1 to C1 (total monomer amount 1) to the sum of the total amounts of second polymerization stage monomers A2 to C2 (total monomer amount 2) is in the range 5:95 to 70:30, the amount of chain transfer agent in the second polymerization stage is selected such that the resulting overall polymer has a weight-average molecular weight of ?15 000 and ?50 000 g/mol, and the amount of the dispersing assistant is ?3.0 wt %, based on the sum of total monomer amount 1 and total monomer amount 2 (total monomer amount).

Abstract: The present invention describes new crosslinkers for coating compositions, their preparation, and their use.

Abstract: The present invention relates to improved water-dispersible polyisocyanates, which feature not only high ease of incorporation into aqueous polyol dispersions, even at low shear rates, for example by hand-incorporation, but also improved optical properties.

Abstract: Two-component coating compositions comprising a water-dispersible polyisocyanate component, comprising c) at least one polyisocyanate and d) at least one reaction product of at least one polyisocyanate b1) with compounds b2) having at least one hydrophilic, non-isocyanate-reactive group (group A) and at least one isocyanate-reactive group (group B) and a polyacrylate component comprising an aqueous polymer dispersion c) of at least one hydroxy-functional poly(meth)acrylate with bimodal or polymodal particle size distribution.

Abstract: Mixture comprising a) at least one polyisocyanate, b) at least one reaction product of at least one polyisocyanate b1) with at least one compound b2) having at least one hydrophilic group which is not reactive toward isocyanate (group A) and precisely one group which is reactive toward isocyanate (group B) ?and c) dioxolane.

Abstract: The present invention relates to improved water-dispersible polyisocyanates with enhanced gloss, more particularly for two-component polyurethane coating materials.

Abstract: The present invention relates to the use of two-component coating compositions comprising isocyanurates of pentamethylene diisocyanate and NCO group reactive compounds with rapid curing and good chemical resistance at temperatures to 80° C.

Abstract: The invention relates to new, water-emulsifiable isocyanates, to a process for preparing water-emulsifiable isocyanates, and to the use thereof.