Patents by Inventor Frederic MARC-KREUCHER

Frederic MARC-KREUCHER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of detecting a microorganism in a sample by a fluorescence based detection method
    Patent number: 10526663
    Abstract: The present invention relates to a method of detecting a microorganism, in particular Staphylococcus aureus, in a sample, comprising the steps of a) incubating the sample with a slow off-rate modified aptamer (SOMAmer) comprising a fluorescent label, b) optionally washing the sample, c) analyzing the sample by a fluorescence-based detection method. The invention further relates to a slow off-rate modified aptamer comprising a fluorescent label, wherein the SOMAmer comprises a nucleotide sequence specific for Staphylococcus aureus, its use for detecting Staphylococcus aureus cells in a sample, and to a microarray or biosensor and a kit comprising at least one of such SOMAmers comprising a fluorescent label.
    Type: Grant
    Filed: February 20, 2015
    Date of Patent: January 7, 2020
    Assignees: Merck Patent GmbH, SOMALOGIC, Inc.
    Inventors: Anne Baumstummler, Frederic Marc-Kreucher, David Lehmann, Urs Ochsner, Nebojsa Janjic
  • METHOD OF DETECTING A MICROORGANISM IN A SAMPLE BY A FLUORESCENCE BASED DETECTION METHOD
    Publication number: 20170051337
    Abstract: The present invention relates to a method of detecting a microorganism, in particular Staphylococcus aureus, in a sample, comprising the steps of a) incubating the sample with a slow off-rate modified aptamer (SOMAmer) comprising a fluorescent label, b) optionally washing the sample, c) analyzing the sample by a fluorescence-based detection method. The invention further relates to a slow off-rate modified aptamer comprising a fluorescent label, wherein the SOMAmer comprises a nucleotide sequence specific for Staphylococcus aureus, its use for detecting Staphylococcus aureus cells in a sample, and to a microarray or biosensor and a kit comprising at least one of such SOMAmers comprising a fluorescent label.
    Type: Application
    Filed: February 20, 2015
    Publication date: February 23, 2017
    Applicants: Merck Patent GmbH, SOMALOGIC, Inc.
    Inventors: Anne BAUMSTUMMLER, Frederic MARC-KREUCHER, David LEHMANN, Urs OCHSNER, Nebojsa JANJIC