Patents by Inventor Frederic Martinet

Frederic Martinet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for enantioselective preparation of sulphoxide derivatives
    Patent number: 7528251
    Abstract: The present invention concerns enantioselective preparation of sulphoxide derivatives or their salts. The method consist in performing an enantioselective oxidation of a sulphur of general formula (I) A —CH2—SB, wherein: A is a diversely substituted pyridinyl ring and B is a heterocyclic radical comprising an imidazo-pyridinyl ring, using an oxidizing agent in the presence of a titanium (IV)-based catalyst and a chiral ligand consisting of a cyclic beta or gamma-amino-alcohol, in an organic solvent, followed, if required, by salt formation with a base. The invention is useful for preparing sulphoxides useful in therapeutics.
    Type: Grant
    Filed: October 5, 2005
    Date of Patent: May 5, 2009
    Assignee: Sidem Pharma SA
    Inventors: Avraham Cohen, Suzy Charbit, François Schutze, Frédéric Martinet, Patricia Gizecki
  • Monohydrated sodium salt of S-tenatoprazole and the use thereof in therapy
    Patent number: 7402593
    Abstract: The present invention relates to S-tenatoprazole monohydrated sodium salt, represented by the following formula and the use thereof in therapy for the treatment of digestive diseases.
    Type: Grant
    Filed: June 17, 2005
    Date of Patent: July 22, 2008
    Assignee: Sidem Pharma
    Inventors: Avraham Cohen, François Schutze, Suzy Charbit, Frédéric Martinet, Hervé Ficheux, Michel Homerin
  • Method For Enantioselective Preparation Of Sulphoxide Derivatives
    Publication number: 20070299261
    Abstract: The present invention concerns enantioselective preparation of sulphoxide derivatives or their salts. The method consist in performing an enantioselective oxidation of a sulphur of general formula (I) A-CH2—SB, wherein: A is a diversely substituted pyridinyl ring and B is a heterocyclic radical comprising an imidazo-pyridinyl ring, using an oxidizing agent in the presence of a titanium (IV)-based catalyst and a chiral ligand consisting of a cyclic beta or gamma-amino-alcohol, in an organic solvent, followed, if required, by salt formation with a base. The invention is useful for preparing sulphoxides useful in therapeutics.
    Type: Application
    Filed: October 5, 2005
    Publication date: December 27, 2007
    Applicant: SIDEM PHARMA SA
    Inventors: Avraham Cohen, Suzy Charbit, Francois Schutze, Frederic Martinet, Patricia Gizecki
  • Monohydrated sodium salt of s-tenatoprazole and the use thereof in therapy
    Publication number: 20070179176
    Abstract: The present invention relates to S-tenatoprazole monohydrated sodium salt, represented by the following formula and the use thereof in therapy for the treatment of digestive diseases.
    Type: Application
    Filed: June 17, 2005
    Publication date: August 2, 2007
    Inventors: Avraham Cohen, Francois Schutze, Suzy Charbit, Frederic Martinet, Herve Ficheux, Michel Homerin
  • Method for the enantioselective preparation of sulphoxide derivatives
    Publication number: 20060281782
    Abstract: The invention relates to a method for the enantioselective preparation of substituted sulphoxide derivatives. The method comprises carrying out an enantioselective oxidation of a sulphide of general formula (I): A-CH2—S—B (I), where A=a variously-substituted pyridyl nucleus and B=a heterocyclic group with a benzimidazole or imidazopyrdyl nucleus, by means of an oxidising agent in the presence of a catalyst based on tungsten or vanadium and a chiral ligand, followed, where necessary, by salt formation with a base to give the sulphoxide: A-CH2—SO—B (Ia). The above is of application to the enantioselective preparation of compounds such as the enantiomers of tenatoprazole and other comparable sulphoxides.
    Type: Application
    Filed: March 26, 2004
    Publication date: December 14, 2006
    Inventors: Avraham Cohen, Suzy Charbit, Francois Schutze, Frederic Martinet