Abstract: A single-use bioreactor or container including an enclosure provided for containing a biological medium, and at least one device for making at least one impedance measurement in a physical, physico-chemical and/or biological process in this medium. The sensing device is fixed through a wall of the enclosure in such a way as to be an integral part thereof and includes a detection part in direct contact with an inside of the bioreactor or container and a connection part extending towards an outside of the enclosure.

Abstract: A single use bioreactor or container including an enclosure provided for containing a biological medium, and at least one device for making at least one impedance measurement in a physical, physico-chemical and/or biological process in this medium. The sensing device is fixed through a wall of the enclosure in such a way as to be an integral part thereof and includes a detection part in direct contact with an inside of the bioreactor or container and a connection part extending towards an outside of the enclosure.

Abstract: A process for on-line and in situ counting of cells in a biological culture medium, comprising the following steps: a plurality of measurements of the capacitance of the medium or a plurality of measurements of the conductance of the medium, at distinct frequencies varying within a predetermined range of measurement frequencies, an extraction of information on the variation of permittivity due to the ?-dispersion in the medium, from the capacitance measurements, and processing of the variation of this information on the variation of permittivity as a function of the frequency, in order to provide information regarding the counting of cells in the medium.

Abstract: Method for biomass determination in a medium, in particular a medium containing biological cells suspended in a conductive fluid, the biomass concentration (X) being obtained from a difference between a first capacitance signal (C?1) of the medium, measured at a first frequency, and a second capacitance signal (C?2) of the medium, measured at a second frequency. The method includes a separate correction of each of the measured signals, based at least on one correction level, the first correction level including a correction of the signals measured in accordance with a model dependent on the conductance of the medium at the first and second frequencies. The invention is useful in biomass measurement systems.

Abstract: A device for capacitive measurement by a floating bridge, including: a sensor module including at least one measuring electrode and at least one guard electrode arranged close to a target connected to a general earth, at least one integrated circuit for capacitive measurement, provided with a guard to which the guard electrode is connected, having an input connected to the measuring electrode, a guard connected to the reference earth of the integrated circuit, an excitation output connected to the general earth, a measurement output, and structure for supplying the integrated circuit for capacitive measurement in floating mode.

Abstract: A device for determining the characteristics of a biomass, includes: a probe (S,S′) including electrodes, two or four in number, for injecting a current into a medium containing biological cells and for reading the voltage applied to the medium, and a resistance for measuring the injected current; a conditioning unit (10) including an alternating voltage generator (112) and a circuit (200) processing current and voltage measuring signals, so as to deliver signals (C,G) respectively of measurement of the capacity and conductance of the medium. The conditioning unit (10) includes a zero method measuring bridge (150) automatically controlled to deliver the signals (C,G) of measurement of the medium capacity and conductance. The invention is useful for characterizing media containing biological cells, in particular for controlling biological fermentation process.