Abstract: Methods for preventing esophageal stricture following an endoscopic resection procedure in a subject are provided. A solution having a pH level of about 3.5 and including a self-assembling peptide comprising between about 7 amino acids and about 32 amino acids in an effective amount and in an effective concentration to form a hydrogel under esophageal conditions to provide prevention of esophageal stricture may be introduced to a target site.

Abstract: The invention relates to a prosthetic device intended for being implanted in a patient's gastrointestinal tract, said device comprising: an inflatable gastric balloon, the volume of which is modulatable; a duodenal prosthesis comprising a pre-pyloric flange and a flexible tubular body. According to the invention, such a device is characterized in that it comprises a system for coupling said balloon to said duodenal prosthesis; said duodenal prosthesis is compressible and expandable in a radial direction; said prosthesis has a wall that is fixedly attached, on at least one part of its length, to a helical frame and said helix has an irregular pitch.

Abstract: An ultrasound applicator for heating, via an internal path, an ultrasound absorbent medium, includes an application head having a longitudinal axis and including at least one ultrasonic transducer having a planar emission face and an opposite face, a leakproof membrane which overlays and is spaced from the emission face, and which is transparent to ultrasound, and means for preventing propagation of ultrasound from the opposite face; means for remotely connecting the transducer to an electricity generator; and means for providing ultrasound coupling with the membrane. The planar emission face emits ultrasound waves through the membrane and in a direction that is substantially perpendicular to the emission face, such that the waves emitted are substantially planar and do not diverge in the vicinity of the transducer and the application head.