Abstract: There is provided a system and method of process window qualification. The method includes obtaining a wafer comprising a plurality of dies respectively printed under a plurality of process window conditions characterized by varying values of focus and exposure, wherein the wafer is fabricated in accordance with a chip design containing a pattern of interest (POI) comprising a surface structure and an underneath structure; inspecting the wafer at POI locations to obtain a plurality of images each capturing an occurrence of the POI; and providing a group of measurements from the plurality of images, comprising, for each given image: extracting a surface contour of the surface structure and an underneath contour of the underneath structure; shifting one of the contours relative to the other one or more times to simulate one or more overlay variations; and measuring a critical metric between the contours following each shift.

Abstract: The invention concerns a method for free solution capillary electrophoresis at an alkaline pH to analyze samples comprising haemoglobin, in which the sample is passed through a capillary containing an analysis buffer, comprising at least one step in which the sample is introduced into a capillary tube containing a solution of analysis buffer, characterized in that the buffer is of the zwitterionic type and in that it is associated with at least one flow inhibitor. It also concerns the use of EC flow inhibitors associated with at least one zwitterionic buffer, and a kit for analyzing haemoglobin by capillary electrophoresis.

Abstract: The invention concerns a free solution capillary electrophoresis method at alkaline pH for the analysis of samples comprising protein constituents including a lipoprotein constituent or constituents, characterized in that it comprises at least one step in which the sample is introduced into a capillary tube containing an analysis buffer, said analysis buffer further comprising at least one anionic surfactant type additive that is capable of hydrophobic interaction with the lipoprotein constituent(s) and of modifying the electrophoretic mobility. The method also concerns a composition for capillary electrophoresis and a kit for analyzing protein constituents.

Abstract: The invention concerns a method for capillary electrophoretic analysis of a biological sample, comprising using negatively surcharged modified antibodies so that they migrate to a zone located outside the migration zone for proteins from the biological sample when they are separated during electrophoresis, said antibodies having antigenic specificity for a predetermined target protein.

Abstract: The invention concerns an alkaline pH, free solution capillary electrophoresis method for analysing clinical samples comprising protein constituents, characterized in that it comprises at least one step in which the sample is introduced into a capillary tube containing a buffer system comprising, as the buffer, a biological buffer with a pKa at 25° C. in the range 8.8 to 10.7 and at least one additive that can increase the ionic strength of the buffer system.

Abstract: Capillary electrophoresis systems, reagents, and processes for analyzing a sample which includes at least one protein constituent.