Abstract: A method for creating a strategy, which is configured to determine a placement of nucleotides within a primary RNA structure as a function of a detail of a predefined secondary structure. The method includes the following steps: initializing the strategy; providing a task representation, the task representation including structural restrictions of the secondary RNA structure and sequential restrictions of the primary RNA structure; determining a primary candidate RNA sequence with the aid of the strategy as a function of the task representation; adapting the strategy with the aid of a reinforcement learning algorithm in such a way that a total loss is optimized.