Patents by Inventor Frederic Van Gool

Frederic Van Gool has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RECOMBINANT CYTOKINE RECEPTORS AND METHODS OF USE
    Publication number: 20260028388
    Abstract: Provided are recombinant cytokine receptors that comprise an IL-2 intracellular domain and an extracellular domain that binds to a cytokine other than IL-2. Also provided herein are Treg cell comprising recombinant cytokine receptors and methods of use.
    Type: Application
    Filed: July 10, 2023
    Publication date: January 29, 2026
    Applicant: Sonoma Biotherapeutics, Inc.
    Inventors: Joshua BEILKE, James MATTHAEI, Frederic VAN GOOL, Jessica CORTEZ
  • TETHERED INTERLEUKIN-2 RECOMBINANT RECEPTORS AND METHODS OF USE
    Publication number: 20250333697
    Abstract: Provided are recombinant cytokine receptors that comprise an IL-2 receptor polypeptide that is tethered to IL-2 cytokine. Also provided herein are Treg cells comprising recombinant cytokine receptors and methods of use.
    Type: Application
    Filed: August 24, 2023
    Publication date: October 30, 2025
    Applicant: Sonoma Biotherapeutics, Inc.
    Inventors: Eleonora TROTTA, Frederic VAN GOOL, James MATTHAEI
  • COMPOSITIONS AND METHODS FOR MODIFYING REGULATORY T CELLS
    Publication number: 20210340496
    Abstract: Provided herein are compositions and methods for modifying regulatory T cells. The inventors have identified nuclear factors that influence expression of Foxp3, a key transcriptional regulator of Treg cells. Treg cells can be modified by inhibiting and/or overexpressing one or more of these nuclear factors to produce stabilized Treg cells or destabilized Treg cells.
    Type: Application
    Filed: October 10, 2019
    Publication date: November 4, 2021
    Applicant: The Regents of the University of California
    Inventors: Alexander Marson, Jessica T. Cortez, Jeffrey A. Bluestone, Eric Shifrut, Frederic Van Gool
  • NEW METHOD FOR THE TREATMENT OF INFLAMMATORY DISEASES
    Publication number: 20090325923
    Abstract: The present invention relates to the use of an inhibitor of the formation of nicotinamide adenyl dinucleotide for the preparation of a medicament used in the treatment of inflammatory diseases such as rheumatoid arthritis and endotoxemia.
    Type: Application
    Filed: September 3, 2007
    Publication date: December 31, 2009
    Applicant: TOPOTARGET SWITZERLAND SA
    Inventors: Oberdan Leo, Thibaut De Smedt, Frederic Van Gool, Mara Galli