Abstract: A system for controlling relative delivery of a therapeutic during a surgical intervention, having: a base; a frame having a proximal end and a distal end; a first subassembly having: a syringe carriage configured to interface with the frame and be moveable relative thereto; a plunger shaft having a proximal end and a distal end, the plunger shaft connected to the frame; and an instrument clamp configured to interact with the plunger shaft; and a syringe having a delivery cannula attached to a syringe body and a syringe plunger, the syringe held by the syringe carriage, where when the syringe plunger is secured to the instrument clamp, the syringe plunger is held in place by the instrument clamp such that the syringe plunger moves relative to the syringe body to cause delivery of a therapeutic as the syringe carriage moves and the delivery cannula is withdrawn.

Abstract: Provided herein are devices, systems, and methods for providing controlled delivery of a therapeutic substance during a surgical procedure, the devices and systems including a base, a frame having a proximal end and a distal end attached to the base, an injection subassembly including a plunger shaft, a relative motion subassembly including a lever plate, and a fastener configured to connect the plunger shaft of the injection subassembly and the lever plate of the relative motion subassembly.

Abstract: A myocyte culture pacing apparatus operating in conjunction with a standard culture dish that permits long term maintenance of cultured myocyte cells over a period of several weeks The device includes a base unit for receiving the culture dish, and an electrode unit for placement atop the culture dish which can receive the cover of the culture dish. The electrode unit has a first and a second planar conductive electrodes extending into each well of the culture dish. The electrodes are planar and extend across the width of the well and are connected to electrical connector for connection to an external electronic unit, which supplies the a variety of electrical pulse regimes to pace the myocyte cultures. The electronic unit permits the type, frequency, duration, voltage and the current of the pulses to be varied in accordance with the desired pacing regime.