Patents by Inventor Frederick Aono

Frederick Aono has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Continuous process for the separation of biologic components from heterogeneous cell populations
    Patent number: 5916743
    Abstract: A method combining the techniques of immunoaffinity separation and continuous flow centrifugal separation is provided for selective separation of a nucleated heterogeneous cell population from a heterogeneous cell mixture. The heterogeneous cell mixture is intimately contacted to promote binding thereto by particles having attached a substance that actively binds to a specific desired type of cell out of the cell mixture. The particles are selected so that the sedimentation velocity of the particle/cell conjugate differs sufficiently from those of other cells in the cell mixture to allow its separation by means of a continuous flow cell separator.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: June 29, 1999
    Assignee: Baxter International Inc.
    Inventors: William C. Lake, Richard Giesler, Dennis Van Epps, John R. Chapman, Jeffrey A. Martinson, Dale R. Ellis, Frederick Aono, Daniel F. Bischof
  • Continuous centrifugation process for the separation of biological components from heterogeneous cell populations
    Patent number: 5641622
    Abstract: A method combining the techniques of immunoaffinity separation and continuous flow centrifugal separation is provided for selective separation of a nucleated heterogeneous cell population from a heterogeneous cell mixture. The heterogeneous cell mixture is intimately contacted to promote binding thereto by particles having attached a substance that actively binds to a specific desired type of cell out of the cell mixture. The particles are selected so that the sedimentation velocity of the particle/cell conjugate differs sufficiently from those of other cells in the cell mixture to allow its separation by means of a continuous flow cell separator.
    Type: Grant
    Filed: June 7, 1994
    Date of Patent: June 24, 1997
    Assignee: Baxter International Inc.
    Inventors: William C. Lake, Richard Giesler, Dennis Van Epps, John R. Chapman, Jeffrey A. Martinson, Dale R. Ellis, Frederick Aono, Daniel F. Bischof