Patents by Inventor Frederick D. Sancilio

Frederick D. Sancilio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11351182
    Abstract: According to various embodiments of this disclosure, pharmaceutical compositions comprising solubilized estradiol are provided. In various embodiments, such compositions are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Grant
    Filed: March 27, 2020
    Date of Patent: June 7, 2022
    Assignee: TherapeuticsMD, Inc.
    Inventors: Brian A. Bernick, Thorsteinn Thorsteinsson, Peter H. R. Persicaner, Janice Louise Cacace, Frederick D. Sancilio, Neda Irani, Julia Amadio
  • Patent number: 11304959
    Abstract: According to various embodiments of this disclosure, pharmaceutical compositions comprising solubilized estradiol are provided. In various embodiments, such compositions are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Grant
    Filed: January 17, 2020
    Date of Patent: April 19, 2022
    Assignee: TherapeuticsMD, Inc.
    Inventors: Brian A. Bernick, Thorsteinn Thorsteinsson, Peter H. R. Persicaner, Janice Louise Cacace, Frederick D. Sancilio, Neda Irani, Julia Amadio
  • Patent number: 11241445
    Abstract: According to various embodiments of this disclosure, pharmaceutical compositions comprising solubilized estradiol are provided. In various embodiments, such compositions are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Grant
    Filed: March 27, 2020
    Date of Patent: February 8, 2022
    Assignee: TherapeuticsMD, Inc.
    Inventors: Brian A. Bernick, Thorsteinn Thorsteinsson, Peter H. R. Persicaner, Janice Louise Cacace, Frederick D. Sancilio, Neda Irani, Julia Amadio
  • Patent number: 11166963
    Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
    Type: Grant
    Filed: August 16, 2018
    Date of Patent: November 9, 2021
    Assignee: THERAPEUTICSMD, INC.
    Inventors: Brian A. Bernick, Janice Louise Cacace, Peter H. R. Persicaner, Neda Irani, Julia M. Amadio, Frederick D. Sancilio
  • Publication number: 20210322359
    Abstract: Described herein are compositions including at least one omega-3 fatty acid (either in the triglyceride, ester or free fatty acid ester form) and at least one surface active agent; wherein the compositions form micelles when in contact with an aqueous medium. Also provided are methods of administering to a subject a composition including at least one omega-3 fatty acid (either in the triglyceride, ester or free fatty acid ester form) and at least one surface active agent, wherein the compositions form micelles when in contact with an aqueous medium, and the bioavailability of the omega-3 fatty acid is substantially independent of a food effect.
    Type: Application
    Filed: January 19, 2021
    Publication date: October 21, 2021
    Applicant: MICELLE BIOPHARMA, INC.
    Inventors: Frederick D. Sancilio, Thorsteinn Thorsteinsson, Glynis Daniel-Archibald, Miguel Lopez-Toledano, Ahmed Abd Almalik Ahmed Mohammed Daak
  • Publication number: 20210322360
    Abstract: Described herein are compositions including at least one omega-3 fatty acid (either in the triglyceride, ester or free fatty acid ester form) and at least one surface active agent; wherein the compositions form micelles when in contact with an aqueous medium. Also provided are methods of administering to a subject a composition including at least one omega-3 fatty acid (either in the triglyceride, ester or free fatty acid ester form) and at least one surface active agent, wherein the compositions form micelles when in contact with an aqueous medium, and the bioavailability of the omega-3 fatty acid is substantially independent of a food effect.
    Type: Application
    Filed: January 25, 2021
    Publication date: October 21, 2021
    Applicant: MICELLE BIOPHARMA, INC.
    Inventors: Frederick D. Sancilio, Thorsteinn Thorsteinsson, Glynis Daniel-Archibald, Miguel Lopez-Toledano, Ahmed Abd Almalik Ahmed Mohammed Daak
  • Patent number: 11123283
    Abstract: According to various embodiments of this disclosure, pharmaceutical formulations comprising solubilized estradiol are provided. In various embodiments, such formulations are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Grant
    Filed: April 1, 2020
    Date of Patent: September 21, 2021
    Assignee: TherapeuticsMD, Inc.
    Inventors: Brian A. Bernick, Julia M. Amadio, Peter H. R. Persicaner, Thorsteinn Thorsteinsson, Janice Louise Cacace, Frederick D. Sancilio, Neda Irani
  • Patent number: 11116717
    Abstract: According to various embodiments of this disclosure, pharmaceutical formulations comprising solubilized estradiol are provided. In various embodiments, such formulations are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Grant
    Filed: April 1, 2020
    Date of Patent: September 14, 2021
    Assignee: TherapeuticsMD, Inc.
    Inventors: Brian A. Bernick, Julia M. Amadio, Peter H. R. Persicaner, Thorsteinn Thorsteinsson, Janice Louise Cacace, Frederick D. Sancilio, Neda Irani
  • Patent number: 11103516
    Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
    Type: Grant
    Filed: May 27, 2020
    Date of Patent: August 31, 2021
    Inventors: Brian A. Bernick, Janice Louise Cacace, Peter H. R. Persicaner, Neda Irani, Julia M. Amadio, Frederick D. Sancilio
  • Patent number: 11065197
    Abstract: According to various embodiments of this disclosure, pharmaceutical formulations comprising solubilized estradiol are provided. In various embodiments, such formulations are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Grant
    Filed: April 1, 2020
    Date of Patent: July 20, 2021
    Assignee: TherapeuticsMD, Inc.
    Inventors: Brian A. Bernick, Julia M. Amadio, Peter H. R. Persicaner, Thorsteinn Thorsteinsson, Janice Louise Cacace, Frederick D. Sancilio, Neda Irani
  • Patent number: 10912783
    Abstract: Compositions and methods for the solubilization of steroid hormones are disclosed.
    Type: Grant
    Filed: May 2, 2019
    Date of Patent: February 9, 2021
    Assignee: THERAPEUTICSMD, INC.
    Inventors: Thorsteinn Thorsteinsson, Frederick D. Sancilio, Brian A. Bernick, Julia M. Amadio
  • Patent number: 10898458
    Abstract: Described herein are compositions including at least one omega-3 fatty acid (either in the triglyceride, ester or free fatty acid ester form) and at least one surface active agent; wherein the compositions form micelles when in contact with an aqueous medium. Also provided are methods of administering to a subject a composition including at least one omega-3 fatty acid (either in the triglyceride, ester or free fatty acid ester form) and at least one surface active agent, wherein the compositions form micelles when in contact with an aqueous medium, and the bioavailability of the omega-3 fatty acid is substantially independent of a food effect.
    Type: Grant
    Filed: May 26, 2017
    Date of Patent: January 26, 2021
    Assignee: Micelle BioPharma, Inc.
    Inventors: Frederick D. Sancilio, Thorsteinn Thorsteinsson, Glynis Daniel-Archibald, Miguel Lopez-Toledano, Ahmed Abd Almalik Ahmed Mohammed Daak
  • Patent number: 10894027
    Abstract: Described herein are compositions including at least one omega-3 fatty acid (either in the triglyceride, ester or free fatty acid ester form) and at least one surface active agent; wherein the compositions form micelles when in contact with an aqueous medium. Also provided are methods of administering to a subject a composition including at least one omega-3 fatty acid (either in the triglyceride, ester or free fatty acid ester form) and at least one surface active agent, wherein the compositions form micelles when in contact with an aqueous medium, and the bioavailability of the omega-3 fatty acid is substantially independent of a food effect.
    Type: Grant
    Filed: October 17, 2019
    Date of Patent: January 19, 2021
    Assignee: Micelle BioPharma, Inc.
    Inventors: Frederick D. Sancilio, Thorsteinn Thorsteinsson, Glynis Daniel-Archibald, Miguel Lopez-Toledano, Ahmed Abd Almalik Ahmed Mohammed Daak
  • Patent number: 10888516
    Abstract: According to various embodiments of this disclosure, pharmaceutical formulations comprising solubilized estradiol are provided. In various embodiments, such formulations are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Grant
    Filed: March 27, 2020
    Date of Patent: January 12, 2021
    Assignee: TherapeuticsMD, Inc.
    Inventors: Brian A. Bernick, Julia M. Amadio, Peter H. R. Persicaner, Thorsteinn Thorsteinsson, Janice Louise Cacace, Frederick D. Sancilio, Neda Irani
  • Publication number: 20200352961
    Abstract: According to various embodiments of this disclosure, pharmaceutical formulations comprising solubilized estradiol are provided. In various embodiments, such formulations are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Application
    Filed: April 1, 2020
    Publication date: November 12, 2020
    Applicant: TherapeuticsMD, Inc.
    Inventors: Brian A. BERNICK, Julia M. AMADIO, Peter H.R. PERSICANER, Thorsteinn THORSTEINSSON, Janice Louise CACACE, Frederick D. SANCILIO, Neda IRANI
  • Publication number: 20200323881
    Abstract: According to various embodiments of this disclosure, pharmaceutical formulations comprising solubilized estradiol are provided. In various embodiments, such formulations are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Application
    Filed: June 25, 2020
    Publication date: October 15, 2020
    Inventors: Brian A. Bernick, Julia M. Amadio, Peter H.R. Persicaner, Thorsteinn Thorsteinsson, Janice Louise Cacace, Frederick D. Sancilio, Neda Irani
  • Publication number: 20200297736
    Abstract: According to various embodiments of this disclosure, pharmaceutical compositions comprising solubilized estradiol are provided. In various embodiments, such compositions are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Application
    Filed: March 27, 2020
    Publication date: September 24, 2020
    Applicant: TherapeuticsMD, Inc.
    Inventors: Brian A. BERNICK, Thorsteinn THORSTEINSSON, Peter H.R. PERSICANER, Janice Louise CACACE, Frederick D. SANCILIO, Neda IRANI, Julia AMADIO
  • Publication number: 20200297735
    Abstract: According to various embodiments of this disclosure, pharmaceutical compositions comprising solubilized estradiol are provided. In various embodiments, such compositions are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Application
    Filed: March 27, 2020
    Publication date: September 24, 2020
    Applicant: TherapeuticsMD, Inc.
    Inventors: Brian A. BERNICK, Thorsteinn THORSTEINSSON, Peter H.R. PERSICANER, Janice Louise CACACE, Frederick D. SANCILIO, Neda IRANI, Julia AMADIO
  • Publication number: 20200289529
    Abstract: According to various embodiments of this disclosure, pharmaceutical formulations comprising solubilized estradiol are provided.
    Type: Application
    Filed: March 27, 2020
    Publication date: September 17, 2020
    Applicant: TherapeuticsMD, Inc.
    Inventors: Brian A. BERNICK, Julia M. AMADIO, Peter H.R. PERSICANER, Thorsteinn THORSTEINSSON, Janice Louise CACACE, Frederick D. SANCILIO, Neda IRANI
  • Publication number: 20200276210
    Abstract: According to various embodiments of this disclosure, pharmaceutical formulations comprising solubilized estradiol are provided.
    Type: Application
    Filed: May 15, 2020
    Publication date: September 3, 2020
    Applicant: TherapeuticsMD, Inc.
    Inventors: Brian A. BERNICK, Julia M. AMADIO, Peter H.R. PERSICANER, Thorsteinn THORSTEINSSON, Janice Louise CACACE, Frederick D. SANCILIO, Neda IRANI