Patents by Inventor Frederick David King

Frederick David King has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9360410
    Abstract: A method and a particle analyzer are provided for determining a particle size distribution of a liquid sample including particles of a lower size range, particles of an intermediate size range, and particles of an upper size range. A dark-field image frame is captured in which the particles of the lower size range and the particles of the intermediate size range are resolved, and a bright-field image frame is captured in which the particles of the intermediate size range and the particles of the upper size range are resolved. Absolute sizes of the particles of the intermediate size range and the particles of the upper size range are determined from the bright-field image frame. Calibrated sizes of the particles of the lower size range are determined from the dark-field image frame by using the particles of the intermediate size range as internal calibration standards.
    Type: Grant
    Filed: March 24, 2014
    Date of Patent: June 7, 2016
    Assignee: ProteinSimple
    Inventors: Frederick David King, Clark Adrien Merchant, Peter Oma
  • Publication number: 20150070699
    Abstract: A method and a particle analyzer are provided for determining a particle size distribution of a liquid sample including particles of a lower size range, particles of an intermediate size range, and particles of an upper size range. A dark-field image frame is captured in which the particles of the lower size range and the particles of the intermediate size range are resolved, and a bright-field image frame is captured in which the particles of the intermediate size range and the particles of the upper size range are resolved. Absolute sizes of the particles of the intermediate size range and the particles of the upper size range are determined from the bright-field image frame. Calibrated sizes of the particles of the lower size range are determined from the dark-field image frame by using the particles of the intermediate size range as internal calibration standards.
    Type: Application
    Filed: March 24, 2014
    Publication date: March 12, 2015
    Applicant: ProteinSimple
    Inventors: Frederick David King, Clark Adrien Merchant, Peter Oma
  • Patent number: 8681215
    Abstract: A method and a particle analyzer are provided for determining a particle size distribution of a liquid sample including particles of a lower size range, particles of an intermediate size range, and particles of an upper size range. A dark-field image frame is captured in which the particles of the lower size range and the particles of the intermediate size range are resolved, and a bright-field image frame is captured in which the particles of the intermediate size range and the particles of the upper size range are resolved. Absolute sizes of the particles of the intermediate size range and the particles of the upper size range are determined from the bright-field image frame. Calibrated sizes of the particles of the lower size range are determined from the dark-field image frame by using the particles of the intermediate size range as internal calibration standards.
    Type: Grant
    Filed: April 29, 2011
    Date of Patent: March 25, 2014
    Assignee: ProteinSimple
    Inventors: Frederick David King, Clark Adrien Merchant, Peter Oma
  • Publication number: 20120274760
    Abstract: A method and a particle analyzer are provided for determining a particle size distribution of a liquid sample including particles of a lower size range, particles of an intermediate size range, and particles of an upper size range. A dark-field image frame is captured in which the particles of the lower size range and the particles of the intermediate size range are resolved, and a bright-field image frame is captured in which the particles of the intermediate size range and the particles of the upper size range are resolved. Absolute sizes of the particles of the intermediate size range and the particles of the upper size range are determined from the bright-field image frame. Calibrated sizes of the particles of the lower size range are determined from the dark-field image frame by using the particles of the intermediate size range as internal calibration standards.
    Type: Application
    Filed: April 29, 2011
    Publication date: November 1, 2012
    Inventors: Frederick David King, Clark Adrien Merchant, Peter Oma
  • Patent number: 7379577
    Abstract: A system and method for measuring small particles suspended in a fluid are disclosed. The system employs optical imaging using diffraction enlargement. A sample of small particles illuminated by a light source is imaged onto a pixel array of detector elements using an imaging optical system having a reduced magnification not sufficient for forming a large enough image of a smallest particle of interest. A low-aperture imaging optics with NA<0.05 is used to add diffraction enlargement to the image corresponding to at least 5 pixels to enable accurate measurement of images of smallest particles of interest, and to increase an optical sampling volume. Suitably programmed processor is used for determining at least a pixel count for each of the diffraction-enlarged images, and for generating a number, size or distribution of particles accounting for pre-determined diffraction enlargement of particle images of different sizes. The method enables analysis of large samples of small particles in one measurement.
    Type: Grant
    Filed: November 10, 2004
    Date of Patent: May 27, 2008
    Assignee: Brightwell Technologies
    Inventors: Frederick David King, Serge Emile LeBlanc
  • Patent number: 7307721
    Abstract: A particle imaging system and a method provided for analyzing particles in a fluid; the system comprising a means for capturing image data of the fluid within a sample cell, and a means for flow control, a valve and a pump, wherein the fluid within the sample cell is periodically stopped, or slowed down, for image capturing and moved rapidly between image capturing events. Advantageously, the present invention allows to increase exposure times, which is particularly significant for fluorescent imaging at low illumination levels.
    Type: Grant
    Filed: April 13, 2006
    Date of Patent: December 11, 2007
    Assignee: Brightwell Technologies
    Inventor: Frederick David King
  • Patent number: 7217937
    Abstract: The present invention relates to the automatic analysis and identification of different species of particles in a liquid sample using both fluorescent tagging and magnification techniques. A light source at a first wavelength is used to induce the tagged particles to emit light at a second wavelength, while the image thereof is captured on a pixel array of a digital camera. A second camera can be used to capture an image of the particles illuminated at the first wavelength, which is separated from the second wavelength by an optical filter. Alternatively, a second light source emitting pulses of light at the second wavelength, which alternate with the first light source.
    Type: Grant
    Filed: November 18, 2004
    Date of Patent: May 15, 2007
    Assignee: Brightwell Technologies
    Inventor: Frederick David King
  • Patent number: 7064826
    Abstract: The present invention relates to a method for determining a distribution of a parameter, e.g. cross-sectional area, of a particle population for identifying specific types of particles therein. A plurality of images of the particles are detected on a pixel array and a number of pixels in the form of a pixel count is determined for each of the plurality of images of particles. Weighting factors, e.g. a probability which relate values of the parameter to different pixel counts are used to determine the distribution for the parameter of the particle population. The method depends on the facts that the total population to be analyzed contains many particles and is uniformly distributed, over many frames, throughout the optical sampling volume, and that even when substantial uncertainty exists on the parameter value corresponding any individual image, the statistical information which is obtained from many images may be used to provide accurate distributions.
    Type: Grant
    Filed: September 3, 2003
    Date of Patent: June 20, 2006
    Assignee: Brightwell Technologies
    Inventors: Guenadi Rabinski, Serge Emile LeBlanc, Frederick David King
  • Patent number: 4090055
    Abstract: An optical fibre is manufactured by forming a layer of fused silica, which may or may not be doped, on the inner wall of a fused silica tube by producing a plasma in the reactant gases flowing through the tube. By this means a higher temperature can be maintained inside the tube than at the tubes outer wall. The plasma is produced at substantially atmospheric pressure. Cooling gas is passed along the outer wall of the tube.
    Type: Grant
    Filed: February 14, 1977
    Date of Patent: May 16, 1978
    Assignee: Northern Telecom Limited
    Inventor: Frederick David King
  • Patent number: 4067642
    Abstract: Modal dispersion and chromatic material dispersion in a multimode optical fiber is reduced by feeding the rays of the light beam into the end of the optical fiber the angle of each ray relative to the axis of the fiber varied in accordance with the wavelength of the ray. The shortest ray is fed at a zero angle and the longest wavelength at angle of .phi. max. .phi. max. is defined by the equation ##EQU1##This invention relates to the reduction of both modal and chromatic material dispersion in a multimode optical fibre.Multimode guides are currently used in fibre-bundle optical communications and will also appear in the next generation of individual-fibre systems. Their 50 to 100.mu.m diameter cores are compatible with multimode LED sources and simple connecting and tapping techniques.
    Type: Grant
    Filed: August 3, 1976
    Date of Patent: January 10, 1978
    Assignee: Northern Telecom Limited
    Inventors: Frederick David King, Felix Paul Kapron
  • Patent number: 3981023
    Abstract: A light emitting diode structure has one or more convex lens formations formed on the surface through which the light issues to provide larger incident angles and reduce internal reflection. Conveniently the structure comprises a multi-layer epitaxially grown structure, and the lens or lenses may be formed integral with the outer surface.
    Type: Grant
    Filed: September 16, 1974
    Date of Patent: September 14, 1976
    Assignee: Northern Electric Company Limited
    Inventors: Frederick David King, Anthony John Springthorpe
  • Patent number: 3962714
    Abstract: An optical modulator comprises a metal insulator semiconductor diode having a predetermined reverse bias. In a particular form the modulator comprises an active layer and a confining layer epitaxially grown sequentially on a substrate. In a particular application a monolithic light emitting diode -- modulator structure can be formed.
    Type: Grant
    Filed: September 19, 1974
    Date of Patent: June 8, 1976
    Assignee: Northern Electric Company Limited
    Inventor: Frederick David King
  • Patent number: 3959808
    Abstract: A variable stripe width semiconductor laser is provided in which, in addition to the contact stripe and back contact, a third contact is provided. By applying a positive bias to the third contact the current spread in the device is reduced, increasing the effective current density at the lasing position. By varying, or pulsing, the applied position bias the current density can be caused to vary above and below a threshold and switch the laser on and off. Further, by application of a suitable positive bias, unwanted higher order modes can be eliminated.
    Type: Grant
    Filed: September 19, 1974
    Date of Patent: May 25, 1976
    Assignee: Northern Electric Company Limited
    Inventor: Frederick David King