Abstract: Methods and apparatuses to provide extension to a groupware client to enable the groupware client to access a workflow of a business process from the context of the groupware client. An enterprise server that manages the workflow can interface with the groupware client to provide action on the workflow from within the context of the groupware client. The enterprise server passes the action to the enterprise backend to implement the action on the workflow. Thus, action on the workflow from the groupware client affects the workflow on the enterprise level. Status information about the workflow may be persisted in the groupware client to enable continued interaction with the workflow from within the groupware client.

Abstract: A pharmaceutical composition comprising an ultrasonicated formulation of .alpha.-lipoic acid and an aqueous solution which may also contain other antioxidants and/or metal chelators is disclosed.Also disclosed is a method of ultrasonically preparing pure or mixed micelles of lipid-soluble antioxidants and .alpha.-lipoic acid in aqueous solutions for intravenous delivery to mitigate microvascular dysfunction in hemorrhagic shock and other conditions of acute microvascular injury.