Abstract: The present invention relates to ionic electrodes, particularly microelectrodes and electrode arrays, and also relates to fabrication methods for such electrodes. In particular, the present invention relates to planar polymer electrodes for making patch clamp measurements of ionic currents through biological membranes, such as the plasma membranes of living cells. The electrodes of the present invention are useful for measuring individual and multisite cell membrane currents and voltages, as well as in high-throughput screening procedures.

Abstract: The present invention relates to ionic electrodes, particularly microelectrodes and electrode arrays, and also relates to fabrication methods for such electrodes. In particular, the present invention relates to planar polymer electrodes for making patch clamp measurements of ionic currents through biological membranes, such as the plasma membranes of living cells. The electrodes of the present invention are useful for measuring individual and multisite cell membrane currents and voltages, as well as in high-throughput screening procedures.

Abstract: The present invention relates to ionic electrodes, particularly microelectrodes and electrode arrays, and also relates to fabrication methods for such electrodes. In particular, the present invention relates to planar polymer electrodes for making patch clamp measurements of ionic currents through biological membranes, such as the plasma membranes of living cells. The electrodes of the present invention are useful for measuring individual and multisite cell membrane currents and voltages, as well as in high-throughput screening procedures.

Abstract: A structural body is monitored in angular position about at least one axis by utilizing a level sensor and a sensor responsive to angular motion of the body about the axis being monitored. An output indicative of long term angular variations of the body about the axis is provided by the level sensor and short term angular variations are indicated by the output from the sensor responsive to angular motion about the axis. The signals indicative of long term and short term angular variations are combined to provide a broad band output signal indicative of angular position which is immune to high frequency translational variations appearing at the level sensor output, but which is responsive to high frequency angular inputs. The fast response angular sensor output is compared with the slow response level sensor output and an error signal is produced which drives the angular sensor output signal into coincidence with the level sensor output signal.

Abstract: An electronic circuit and method used in conjunction with transducers for eliminating noise signals which includes an AC source of excitation for first and second transducer coils, called pickoff coils located in first and second signal channels. Output from the pickoffs is supplied to detectors disposed in each of the signal channels. The detected pickoff output signals are filtered and connected to a summing circuit wherein the internally generated noise from the AC source appearing as common mode signals in both signal channels is cancelled and differential mode signals produced in said channels are added to produce an output.