Patents by Inventor Frederick John Livesey

Frederick John Livesey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TAU EPITOPE AND BINDING MOLECULES
    Publication number: 20230192826
    Abstract: The invention relates to isolated recombinant peptides comprising an epitope from human tau 2N4R. The invention also relates to use of such peptides to generate binding molecules, such as antibodies, specific for the tau epitope and to such peptides and antibodies for use in investigation, diagnosis and treatment of tauopathies, such as Alzheimer’s disease.
    Type: Application
    Filed: June 29, 2020
    Publication date: June 22, 2023
    Applicant: Gen2 Neuroscience Limited
    Inventors: Frederick John Livesey, Clare Jones
  • TAU EPITOPE AND BINDING MOLECULES
    Publication number: 20220265819
    Abstract: The invention relates to isolated synthetic or recombinant peptides comprising an epitope of human tau 2N4R, wherein the tau peptide sequence comprising the epitope is not phosphorylated. The invention also relates to use of such peptides to generate binding molecules, such as antibodies, specific for the non-phosphorylated tau epitopes and to such peptides and binding molecules, such as antibodies, for use in investigation, diagnosis and treatment of tauopathies, such as Alzheimer's disease.
    Type: Application
    Filed: July 6, 2020
    Publication date: August 25, 2022
    Applicant: Gen2 Neuroscience Limited
    Inventors: Frederick John Livesey, Clare Jones
  • Corticogenesis of Human Pluripotent Cells
    Publication number: 20130149287
    Abstract: This invention relates to in vitro methods for the induction of corticogenesis in human pluripotent cells, such as iPS cells, by culturing the cells under conditions which stimulate retinoid signalling and inhibit TGF? superfamily signalling. This may be useful in production of cortical neurons, in particular patient-specific cortical neurons; the modelling of juvenile and adult-onset neurological diseases; and the development of therapeutics.
    Type: Application
    Filed: July 29, 2011
    Publication date: June 13, 2013
    Applicant: Cambridge Enterprise Limited
    Inventors: Frederick John Livesey, Yichen Shi