Abstract: Methods for purifying RNA from a sample, comprising one or more steps of tangential flow filtration, hydroxyapatite chromatography, core bead flow-through chromatography, or any combinations thereof. These techniques are useful individually, but show very high efficiency when used in combination, or when performed in particular orders. The methods can purify RNA in a highly efficient manner without unduly compromising potency or stability, to provide compositions in which RNA is substantially cleared of contaminants. Moreover, they can be performed without the need for organic solvents.

Abstract: Methods for purifying RNA from a sample, comprising one or more steps of tangential flow filtration, hydroxyapatite chromatography, core bead flow-through chromatography, or any combinations thereof. These techniques are useful individually, but show very high efficiency when used in combination, or when performed in particular orders. The methods can purify RNA in a highly efficient manner without unduly compromising potency or stability, to provide compositions in which RNA is substantially cleared of contaminants. Moreover, they can be performed without the need for organic solvents.

Abstract: A system and method of adding a high-rate channel to a legacy baseband bus includes a bus communicatively coupled to a transmitter and a receiver via one or more transformer couplers, where the transmitter and receiver transmit and receive a first signal over the bus utilizing a differential mode. The system also includes at least two modems coupled to the bus, where a first modem transmits a second signal over the bus for receipt by a second modem, where the at least two modems are each coupled to the bus via the one or more transformer couplers, where the second signal is transmitted over the bus utilizing a common mode, and where the first signal and the second signal are spatially separated on the bus based on an isolation between the common mode and the differential mode.

Abstract: Methods for purifying RNA from a sample, comprising one or more steps of tangential flow filtration, hydroxyapatite chromatography, core bead flow-through chromatography, or any combinations thereof. These techniques are useful individually, but show very high efficiency when used in combination, or when performed in particular orders. The methods can purify RNA in a highly efficient manner without unduly compromising potency or stability, to provide compositions in which RNA is substantially cleared of contaminants. Moreover, they can be performed without the need for organic solvents.

Abstract: Methods for purifying RNA from a sample, comprising one or more steps of tangential flow filtration, hydroxyapatite chromatography, core bead flow-through chromatography, or any combinations thereof. These techniques are useful individually, but show very high efficiency when used in combination, or when performed in particular orders. The methods can purify RNA in a highly efficient manner without unduly compromising potency or stability, to provide compositions in which RNA is substantially cleared of contaminants. Moreover, they can be performed without the need for organic solvents.

Abstract: A method, computer program product, and system where a processor(s) in a distributed computing environment intercepts a communication (of sequential elements) between a first computing node and a second computing node. The processor(s) determines if the communication is undesired by evaluating data related to or comprising each element individually.

Abstract: The invention provides, inter alia, compositions useful for, e.g., raising an immune response to HIV-1, and associated methods of raising an immune response to HIV in a mammalian subject. In some embodiments, the compositions are bivalent immunogenic compositions comprising two (or, in some embodiments more than two) human immunodeficiency virus (HIV) clade C envelope gp120 polypeptide antigens, together with a liposome-based adjuvant, such as the adjuvant known as AS01.

Abstract: Methods for purifying RNA from a sample, comprising one or more steps of tangential flow filtration, hydroxyapatite chromatography, core bead flow-through chromatography, or any combinations thereof. These techniques are useful individually, but show very high efficiency when used in combination, or when performed in particular orders. The methods can purify RNA in a highly efficient manner without unduly compromising potency or stability, to provide compositions in which RNA is substantially cleared of contaminants. Moreover, they can be performed without the need for organic solvents.

Abstract: The invention provides a method of inhibiting Ran protein activity in at least one eukaryotic cell or cell-free extract, the method comprising exposing an amino acid sequence comprising at least a portion of EMCV or TMEV leader protein, wherein the amino acid sequence comprises SEQ. ID NO: 14 or SEQ. ID NO: 15, to at least one cell in an amount effective to inhibit Ran activity in the targeted cell and evaluating Ran protein activity in the cell.

Abstract: A composition is disclosed comprising virus in a formulation comprising a polyhydroxy hydrocarbon buffered to maintain a pH in a range from about 7 to about 8.5 at a temperature in the range from about 2° C. to 27° C. Methods for concentrating and purifying virus preparations are also disclosed.

Abstract: A composition is disclosed comprising virus in a formulation comprising a polyhydroxy hydrocarbon buffered to maintain a pH in a range from about 7 to about 8.5 at a temperature in the range from about 2° C. to 27° C. Methods for concentrating and purifying virus preparations are also disclosed.

Abstract: A tire pressure monitoring system (12) for a vehicle (10) has a plurality of tires (14a-d) in respective rolling locations having a respective plurality of tire transmitters (16a-d) that generate a respective plurality of transmitter identification signals. A controller (22) is coupled to a counter that counts ignition cycle transitions. The controller enters a learn mode in response to the count and the brake condition signal. The system may also include a display for signaling the vehicle operator to perform a desired action. The controller generates a plurality of display signals on the display indicative of the respective plurality of tire locations and activates a timer when the plurality of transmitter identification signals are received before a predetermined time is counted by the timer.

Abstract: A filter plug tray includes a housing having a loading port which cooperates with external loading and unloading stations, a feed conveyor for conveying filter plugs across the loading port, and expandable filter plug constraining means positioned in the housing to contain the filter plugs in a desired orientation and alignment. The constraining means includes a flexible band wound under tension on a reel rotatably mounted the housing. The flexible band unwinds as plugs are loaded into the tray and winds onto the reel to urge plugs to the loading port as plugs are unloaded.