Patents by Inventor Frederick R. Haselton, III

Frederick R. Haselton, III has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for the selective regulation of DNA and RNA transcription and translation by photoactivation
    Patent number: 6410327
    Abstract: The present invention provides an isolated nucleic acid covalently linked to a photolabile caging group which reversibly prevents expression of the nucleic acid. The present invention further provides a method of selectively expressing a nucleic acid in a cell, comprising: a) covalently linking the nucleic acid to a photolabile caging group which reversibly prevents expression of the nucleic acid; b) introducing the nucleic acid of step (a) into the cell; and c) exposing the cell of step (b) to light, whereby exposure to the light unlinks the nucleic acid and the caging group and the nucleic acid is selectively expressed in the cell.
    Type: Grant
    Filed: April 18, 2001
    Date of Patent: June 25, 2002
    Assignee: Vanderbilt University Office of Technology Transfer
    Inventors: Frederick R. Haselton, III, J. Steven Alexander
  • Methods for the selective regulation of DNA and RNA transcription and translation by photoactivation
    Patent number: 6242258
    Abstract: The present invention provides an isolated nucleic acid covalently linked to a photolabile caging group which reversibly prevents expression of the nucleic acid. The present invention further provides a method of selectively expressing a nucleic acid in a cell, comprising: a) covalently linking the nucleic acid to a photolabile caging group which reversibly prevents expression of the nucleic acid; b) introducing the nucleic acid of step (a) into the cell; and c) exposing the cell of step (b) to light, whereby exposure to the light unlinks the nucleic acid and the caging group and the nucleic acid is selectively expressed in the cell.
    Type: Grant
    Filed: January 5, 2000
    Date of Patent: June 5, 2001
    Assignee: Vanderbilt University
    Inventors: Frederick R. Haselton, III, J. Steven Alexander
  • DMNPE caged nucleic acid and vector
    Patent number: 6017758
    Abstract: The present invention provides an isolated nucleic acid covalently linked to a photolabile caging group which reversibly prevents expression of the nucleic acid. The present invention further provides a method of selectively expressing a nucleic acid in a cell, comprising: a) covalently linking the nucleic acid to a photolabile caging group which reversibly prevents expression of the nucleic acid; b) introducing the nucleic acid of step (a) into the cell; and c) exposing the cell of step (b) to light, whereby exposure to the light unlinks the nucleic acid and the caging group and the nucleic acid is selectively expressed in the cell.
    Type: Grant
    Filed: February 20, 1998
    Date of Patent: January 25, 2000
    Assignee: Vanderbilt University
    Inventors: Frederick R. Haselton, III, J. Steven Alexander