Patents by Inventor Frederick Ramsdell

Frederick Ramsdell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070280942
    Abstract: The present invention provides a newly identified CD28 family member that functions as lymphocyte inhibitory receptor termed pG6b, which is expressed on T cells. Methods and compositions for modulating pG6b-mediated negative signaling and interfering with the interaction of its counter-receptor for therapeutic, diagnostic, and research purposes are also provided.
    Type: Application
    Filed: May 14, 2007
    Publication date: December 6, 2007
    Inventors: Steven Levin, Frederick Ramsdell, Zeren Gao, Edward Howard, David Taft, Janet Johnston, Mark Rixon, LuAnne Hebb
  • Publication number: 20070054360
    Abstract: The present invention provides a newly identified B7 receptor, zB7R1 that functions as lymphocyte inhibitory receptor, which is a PD-1-like molecule and is expressed on T cells. The present invention also provides the discovery of zB7R1's ability to bind to CD155. Methods and compositions for modulating zB7R1-mediated negative signaling and interfering with the interaction of its counter-receptor for therapeutic, diagnostic and research purposes are also provided.
    Type: Application
    Filed: May 12, 2006
    Publication date: March 8, 2007
    Inventors: Zeren Gao, Steven Levin, Janine Bilsborough, James West, Cameron Brandt, Frederick Ramsdell, Edward Howard, Erick Chadwick
  • Publication number: 20070053903
    Abstract: The invention provides pHHLA2 co-receptor polypeptides and functional fragments, antibodies to same, isolated polynucleotides encoding same, vectors containing the polynucleotides, cells containing the vectors. Methods of making and using these co-stimulatory pHHLA2 co-receptors molecules are also disclosed.
    Type: Application
    Filed: May 12, 2006
    Publication date: March 8, 2007
    Inventors: Zeren Gao, Brian Fox, Steven Levin, Frederick Ramsdell, Edward Howard, Janine Bilsborough
  • Publication number: 20060286092
    Abstract: Novel methods of using isolated polypeptides, isolated polynucleotides encoding the polypeptides, and related compositions are disclosed for pNKp30 protein. The methods involved modulating the proliferation of T-cells in vitro and in vivo and modulation of immune response. The present invention also includes methods for producing pNKp30, including soluble molecules, uses therefor and antibodies thereto.
    Type: Application
    Filed: May 12, 2006
    Publication date: December 21, 2006
    Inventors: Zeren Gao, Steven Levin, Christopher Clegg, Jane Gross, Wenfeng Xu, Frederick Ramsdell, Cameron Brandt