Patents by Inventor Frederick Roy Manby

Frederick Roy Manby has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • QUINAZOLINE COMPOUNDS AND METHODS OF USE
    Publication number: 20240092761
    Abstract: Substituted quinazoline compounds, conjugates, and pharmaceutical compositions for use in the treatment of cancer are disclosed herein. The disclosed compounds are useful, among other things, in the inhibition of CDK. In certain aspects, the disclosure generally relates to substituted quinolinone amide compounds or salts of Formula (I), (IA), (IAA), (IAAA), (IB), (IBB), (IC), (ICC), (II), or (IIA) and pharmaceutical compositions thereof.
    Type: Application
    Filed: July 18, 2023
    Publication date: March 21, 2024
    Inventors: William VERNIER, Quynh Nhu NGUYEN, Nomaan REZAYEE, Laurent GOMEZ, Chao Zhang, Thomas Francis MILLER, III, Frederick Roy MANBY
  • AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE
    Publication number: 20240034731
    Abstract: Substituted aza-quinazoline compounds, conjugates, and pharmaceutical compositions for use in the treatment of cancer are disclosed herein. The disclosed compounds are useful, among other things, in the inhibition of CDK. In certain aspects, the disclosure generally relates to substituted quinolinone amide compounds or salts of Formula (I), (IA), (IAA), (IAAA), (IB), (IBB), (IC), (ICC), (ID), (IDD), (IE), and (IEE) and pharmaceutical compositions thereof.
    Type: Application
    Filed: July 24, 2023
    Publication date: February 1, 2024
    Inventors: William VERNIER, Quynh Nhu NGUYEN, Nomaan REZAYEE, Laurent GOMEZ, Chao ZHANG, Thomas Francis MILLER, III, Frederick Roy MANBY
  • Systems and Methods for Determining Molecular Properties with Atomic-Orbital-Based Features
    Publication number: 20220165364
    Abstract: Systems and methods for determining molecular structures based on atomic-orbital-based features are described. Atomic-orbital-based features can be utilized in combination with machine-learning methods to predict accurate properties, such as quantum mechanical energy, of molecular systems.
    Type: Application
    Filed: May 27, 2021
    Publication date: May 26, 2022
    Applicants: California Institute of Technology, Entos, Inc.
    Inventors: Zhuoran Qiao, Animashree Anandkumar, Thomas Francis Miller, Matthew Gregory Welborn, Frederick Roy Manby, Feizhi Ding, Daniel George Smith, Peter John Bygrave, Sai Krishna Sirumalla, Anders Steen Christensen