Patents by Inventor Frederick W. Holtsberg

Frederick W. Holtsberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunogenic composition comprising a fusion peptide derived from superantigen toxoids
    Patent number: 11826412
    Abstract: The present disclosure provides immunogenic compositions useful in prevention and treatment of Staphylococcus aureus infection. In particular, the disclosure provides multivalent oligopeptides, fusion proteins comprising two or more staphylococcal superantigen (SAg) proteins, or any fragments, variants, or derivatives thereof fused together as a single polypeptide in any order.
    Type: Grant
    Filed: February 25, 2022
    Date of Patent: November 28, 2023
    Assignee: ABVACC, Inc.
    Inventors: Mohammad Javad Aman, Thomas Kort, Arundhathi Venkatasubramaniam, Nils Williston, Rajan Prasad Adhikari, Frederick W. Holtsberg
  • IMMUNOGENIC COMPOSITION COMPRISING A FUSION PEPTIDE DERIVED FROM SUPERANTIGEN TOXOIDS
    Publication number: 20220257744
    Abstract: The present disclosure provides immunogenic compositions useful in prevention and treatment of Staphylococcus aureus infection. In particular, the disclosure provides multivalent oligopeptides, fusion proteins comprising two or more staphylococcal superantigen (SAg) proteins, or any fragments, variants, or derivatives thereof fused together as a single polypeptide in any order.
    Type: Application
    Filed: February 25, 2022
    Publication date: August 18, 2022
    Inventors: Mohammad Javad AMAN, Thomas KORT, Arundhathi VENKATASUBRAMANIAM, Nils WILLISTON, Rajan Prasad ADHIKARI, Frederick W. HOLTSBERG
  • Immunogenic composition comprising a fusion peptide derived from superantigen toxoids
    Patent number: 11260120
    Abstract: The present disclosure provides immunogenic compositions useful in prevention and treatment of Staphylococcus aureus infection. In particular, the disclosure provides multivalent oligopeptides, fusion proteins comprising two or more staphylococcal superantigen (SAg) proteins, or any fragments, variants, or derivatives thereof fused together as a single polypeptide in any order.
    Type: Grant
    Filed: July 25, 2018
    Date of Patent: March 1, 2022
    Assignee: INTEGRATED BIOTHERAPEUTIC VACCINES, INC.
    Inventors: Mohammad Javad Aman, Thomas Kort, Arundhathi Venkatasubramaniam, Nils Williston, Rajan Prasad Adhikari, Frederick W. Holtsberg
  • IMMUNOGENIC COMPOSITION COMPRISING A FUSION PEPTIDE DERIVED FROM SUPERANTIGEN TOXOIDS
    Publication number: 20200206335
    Abstract: The present disclosure provides immunogenic compositions useful in prevention and treatment of Staphylococcus aureus infection. In particular, the disclosure provides multivalent oligopeptides, fusion proteins comprising two or more staphylococcal superantigen (SAg) proteins, or any fragments, variants, or derivatives thereof fused together as a single polypeptide in any order.
    Type: Application
    Filed: July 25, 2018
    Publication date: July 2, 2020
    Inventors: Mohammad Javad AMAN, Thomas KORT, Arundhathi VENKATASUBRAMANIAM, Nils WILLISTON, Rajan Prasad ADHIKARI, Frederick W. HOLTSBERG
  • MONOCLONAL ANTIBODIES DIRECTED AGAINST ENVELOPE GLYCOPROTEINS FROM MULTIPLE FILOVIRUS SPECIES
    Publication number: 20170158753
    Abstract: The disclosure provides binding molecules, e.g., antibodies or antigen-binding fragments thereof, that can bind to orthologous epitopes found on two or more filovirus species or strains.
    Type: Application
    Filed: June 24, 2015
    Publication date: June 8, 2017
    Inventors: Mohammad Javad Aman, Frederick W. Holtsberg, Sergey Shulenin, Hong Vu, Katie A. Howell, Kelly Lyn Warfield