Abstract: An injector system includes a powered injector, a pressurizing chamber in operative connection with the powered injection, a fluid path in fluid communication with the pressurizing chamber, and a manual control in fluid connection with the fluid path. The manual control includes at least one actuator for controlling the injector through application of force by an operator. The actuator provides tactile feedback of pressure in the fluid path to the operator via a fluid connection therewith. An injection system for use in angiography includes a source of saline, a pump in fluid connection with the source of saline to pressurized the saline, a source of contrast, a contrast valve in fluid connection with the source of contrast, a powered injector in fluid connection with the contrast valve, and a pressure isolation mechanism.

Abstract: A system for processing cells (and/or other injectate components) includes a container and a plunger adapted to be slidably positioned within the container. The system includes at least one inlet port through which a fluid can enter the system and at least one effluent port through which an effluent can exit the system. The plunger section forms a sealing engagement with the inner wall of the container such that rearward motion of the plunger is adapted to draw fluid into the system via the inlet and forward motion of the plunger is adapted to force effluent out of the system via the effluent port.

Abstract: An injector system includes a powered injector, a pressurizing chamber in operative connection with the powered injection, a fluid path in fluid communication with the pressurizing chamber, and a manual control in fluid connection with the fluid path. The manual control includes at least one actuator for controlling the injector through application of force by an operator. The actuator provides tactile feedback of pressure in the fluid path to the operator via a fluid connection therewith. An injection system for use in angiography includes a source of saline, a pump in fluid connection with the source of saline to pressurized the saline, a source of contrast, a contrast valve in fluid connection with the source of contrast, a powered injector in fluid connection with the contrast valve, and a pressure isolation mechanism.

Abstract: A method and device for the simultaneous or sequential introduction of multiple fluids into the bloodstream including a multiple lumen catheter with corresponding multiple hole sets. By introducing a second fluid such as saline, the concentration and bolus of a first fluid, such as a contrast agent, can be controlled and optimized.

Abstract: A hazardous fluid transport container and a hazardous fluid delivery system are disclosed. The hazardous fluid transport container includes a housing enclosing an at least partially shielded enclosure. First and second fluid path elements are disposed within the housing, with the first fluid path element and second fluid path element fluidly coupled together. A pump unit may be provided for dispensing fluid from the first and second fluid path elements optionally into a third fluid path element. Also, methods for priming the hazardous fluid transport container and for mitigating laminar flow injection bolus spreading are disclosed. Additionally, disclosed is a radioactive fluid transport container for a syringe or other container. The radioactive fluid transport container allows the syringe or container to be used in an injection procedure without removal from the container.

Abstract: A system for delivering fluid to a patient includes a container suitable for holding a fluid and an enclosure to shield the fluid. The system further includes a pump device capable of pumping fluid from the container and delivering the fluid to the patient, and the container adapted to be attachable to the pump device.

Abstract: An assembly for connection to a system for injecting a patient is disclosed. The assembly includes an enclosure, a compartment incorporated into the enclosure, a connector, and an output. The compartment is adapted to accept a pharmaceutical container. At least one sealing member is adapted to reversibly seal the compartment. The connector is adapted to establish a fluid connection with a pharmaceutical container in the compartment. The outlet is in fluid connection with the first connector and adapted to connect to the injector.

Abstract: A system for processing cells is disclosed. The system may include a container having an inner wall, a plunger adapted to be slidably positioned within the container, at least one inlet port through which a fluid can enter the container, at least one outlet port through which a fluid can exit the container, at least one effluent port through which an effluent can exit the container, a first check valve in fluid connection with the inlet port and a second check valve in fluid connection with the effluent port. The plunger may include a filter that allows fluid to pass therethrough but prevents cells from passing therethrough. Rearward motion of the plunger may be adapted to draw fluid into the system via the inlet port and forward motion of the plunger may be adapted to force effluent out of the system via the effluent port.

Abstract: A fluid connector system features a stopper and an extending section. Installable within an outlet of a fluid container, the stopper defines a passage therethrough. Defining air and fluid conduits, the extending section has a first abutment member threadably connectible thereto and a second abutment member affixed thereto. The extending section is adapted to be extended through the passage of the stopper when assembled thereto. When the first abutment member is tightened about the extending section, the first and second abutment members abut against the exterior and interior sides, respectively, of the stopper. With the stopper installed within the outlet and the extending section and the abutment members therewith assembled to the stopper thereby sealing the passage therein, fluid within the container may be extracted via the fluid conduit as air exterior to the container flows therein via the air conduct to displace the fluid being extracted from the container.

Abstract: A combined fluid injection and inflation system is disclosed and includes a fluid delivery system including at least one pressurizing device, a fluid path, and a control unit. The fluid path is adapted to connect the pressurizing device to a patient via a catheter including a balloon and inserted in the patient. The control unit is operable to control the fluid delivery system. In operation, the control unit selectively actuates the fluid delivery system to operate in a fluid injection mode or in a balloon inflation mode. In the fluid injection mode the pressurizing device delivers fluid to the fluid path for a fluid injection procedure. In the balloon inflation mode, the pressurizing device delivers fluid to the fluid path for inflating the balloon associated with the catheter. An operator control may be connected to the control unit for controlling the fluid delivery system and may be a handheld device.

Abstract: An integrated radiopharmaceutical patient treatment system is disclosed including a patient support platform with an associated patient stimulus apparatus, an imager proximate the patient support platform, a radiopharmaceutical fluid delivery system for infusing a radiopharmaceutical fluid into a patient, a patient monitor to be associated with a patient, and an integrated system controller operably associated with the patient stimulus apparatus, imager, radiopharmaceutical fluid delivery system, and patient monitor to control and coordinate their operations. Within the patient treatment system the radiopharmaceutical fluid delivery system may be included comprising a radionuclide supply module, a radiopharmaceutical processing module, a quality control module, a patient injection module, and a controller. A hazardous fluid handling system including a docking station and a hazardous fluid transport device adapted to detachably dock with the docking station is further disclosed.

Abstract: A fluid connector includes an extending section including a spiked end to pierce the container port. The extending section includes at least one air conduit and at least one fluid conduit therethrough. The extending section further includes a first abutment member and second abutment member. The first abutment member is adapted to abut a first or air side of the container port upon piercing of the container port. The second abutment member is spaced from the first abutment member and is adapted to abut a second or fluid sided of the container port. The fluid connector can further include grasping members extending from the extending section to facilitate rotation of the extending section relative to the container port during piercing thereof. The fluid connector can also include a check valve in fluid connection with the air line. In several embodiments, the check valve is positioned within the extending section.

Abstract: A system for processing cells (and/or other injectate components) includes a container and a plunger adapted to be slidably positioned within the container. The system includes at least one inlet port through which a fluid can enter the system and at least one effluent port through which an effluent can exit the system. The plunger section forms a sealing engagement with the inner wall of the container such that rearward motion of the plunger is adapted to draw fluid into the system via the inlet and forward motion of the plunger is adapted to force effluent out of the system via the effluent port.

Abstract: An apparatus for holding a fluid container, such as a syringe or a vial, is provided for securing the container in an upside down or other suitable position for use in various medical procedures such as those of the type that involve use of a medical pump. The fluid container holding apparatus is capable of operatively connecting to any of a number of support structures including a wall, ceiling, desk, table, post, hangar, or IV stand. A fluid delivery system including such a fluid container, and a fluid conduit, such as IV tubing, may include the fluid container holding apparatus of the present invention.

Abstract: A system for injecting a patient, includes a container enclosing a hazardous pharmaceutical; a first pump to deliver a hazardous pharmaceutical to a patient and a fluid path operably connected to the first pump, the container, and the patient. The system further includes a hazardous material containment suitable to confine the hazardous pharmaceutical during connection of the hazardous pharmaceutical container to the fluid path.

Abstract: A method and device for the simultaneous or sequential introduction of multiple fluids into the bloodstream including a multiple lumen catheter with corresponding multiple hole sets. By introducing a second fluid such as saline, the concentration and bolus of a first fluid, such as a contrast agent, can be controlled and optimized.

Abstract: A system for injecting an injectate into patient includes a first pressurizable container for holding the injectate; a patient interface in fluid connection with the first pressurizable container, the patient interface being adapted to pass the injectate into tissue of the patient; a powered injector in operative connection with the first pressurizable container to pressurize the injectate; a controller system in operative connection with powered injector; and a stereotactic localization frame adapted to be placed in operative connection with the patient interface to assist in controlling localization of the patient interface. A system for processing cells (and/or other injectate components) includes a container and a plunger adapted to be slidably positioned within the container. The system includes at least one inlet port through which a fluid can enter the system and at least one effluent port through which an effluent can exit the system.

Abstract: A system for injecting a patient, includes a container enclosing a hazardous pharmaceutical; a first pump to deliver a hazardous pharmaceutical to a patient and a fluid path operably connected to the first pump, the container, and the patient. The system further includes a hazardous material containment suitable to confine the hazardous pharmaceutical during connection of the hazardous pharmaceutical container to the fluid path.

Abstract: A device for injection of a fluid into a patient includes a container adapted to hold the fluid and defining an outlet through which the fluid can exit the container. A pressurizing mechanism is in connection with the container for pressurizing the fluid, and an actuator is in fluid connection with the outlet. The actuator has a first state in which fluid is prevented from flowing through the outlet and a second state in which fluid can flow through the outlet. The injection device further includes a flow regulator to control the flow rate of fluid in fluid connection with the outlet. The container, the pressurizing mechanism, the actuator and the flow regulator can be MR compatible, thereby making the device suitable for use in or near the bore of an MR scanner.

Abstract: Systems, devices, and methods towards improved diagnosis and therapy in connection with central venous catheters (including PICC lines). Included among the many improvements broadly contemplated herein are: arrangements via which a venous catheter can move passively into position in central venous circulation; arrangements via which a catheter can be actively guided without the use of a needle or guide wire; arrangements via which a catheter can be packaged to facilitate easy, rapid, and positionally accurate deployment by medical personnel while maintaining device sterility; and arrangements via which a catheter tip can be imaged during and after insertion.