Patents by Inventor Frederico MINGOZZI

Frederico MINGOZZI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hybrid Recombinant Adeno-Associated Virus Serotype Between AAV9 and AAVrh74 with Reduced Liver Tropism
    Publication number: 20210107948
    Abstract: The invention relates to a recombinant adeno-associated virus (AAV) capsid protein, which is a hybrid between AAV serotype 9 (AAV9) and AAV serotype 74 (AAVrh74) capsid proteins, wherein said recombinant hybrid AAV capsid protein has a reduced liver tropism compared to the parent AAV9 and AAVrh74 capsid proteins. The invention relates also to the derived hybrid AAV serotype vector particles packaging a gene of interest and their use in gene therapy, in particular for treating neuromuscular genetic diseases.
    Type: Application
    Filed: April 4, 2019
    Publication date: April 15, 2021
    Applicants: Genethon, INSERM (Institut National de la Santé et de la Recherche Médicale), Universite d'Evry Val d'Essonne, Sorbonne Universite, Association Institut de Myologie
    Inventors: Isabelle RICHARD, Evelyne GICQUEL, Frederico MINGOZZI, Giuseppe RONZITTI, Patrice VIDAL