Patents by Inventor Frederik Bornke
Frederik Bornke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20110113494Abstract: The present invention relates to serine hydroxymethyltransferase (E.C. 2.1.2.1) as novel target for herbicides, and to nucleic acid sequences encoding a polypeptide with the biological activity of a serine hydroxymethyltransferase, which, when not present, bring about growth retardation symptoms and chlorotic leaves, comprising the nucleic acid sequence SEQ ID No:3, and functional equivalents of the abovementioned nucleic acid sequence or the nucleic acid sequence SEQ ID NO:7 and functional equivalents of the abovementioned nucleic acid sequence. Moreover, the present invention relates to the use of the abovementioned nucleic acid sequences, of functional analogs of the SEQ ID NO:3 or SEQ ID NO:7 or of polypeptides encoded by one of the abovementioned nucleic acid sequences in a method for identifying herbicidally active compounds which inhibit serine hydroxymethyltransferases, and to the use of these compounds which have been identified by the method as herbicides.Type: ApplicationFiled: December 23, 2009Publication date: May 12, 2011Applicant: BASF AktiengesellschaftInventors: Uwe Sonnewald, Frederik Börnke, Kirsten Deist, Marc Stitt Nigel, Wolfgang Lein, Thomas Ehrhardt, Andreas Reindl, Ralf-Michael Schmidt, Annette Freund
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Patent number: 7572950Abstract: The invention relates to methods for generating or increasing a pathogen resistance in plants by expression, preferably pathogen-inducible expression, of a sucrose isomerase.Type: GrantFiled: July 2, 2003Date of Patent: August 11, 2009Assignee: SunGene GmbH & Co. KGaAInventors: Karin Herbers, Bettina Tschiersch, Uwe Sonnewald, Frederik Börnke, Horst-Ekkehard Neuhaus
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Publication number: 20080155716Abstract: The present invention relates to serine hydroxymethyltransferase (E.C. 2.1.2.1) as novel target for herbicides, and to nucleic acid sequences encoding a polypeptide with the biological activity of a serine hydroxymethyltransferase, which, when not present, bring about growth retardation symptoms and chlorotic leaves, comprising the nucleic acid sequence SEQ ID No:3, and functional equivalents of the abovementioned nucleic acid sequence or the nucleic acid sequence SEQ ID NO:7 and functional equivalents of the abovementioned nucleic acid sequence. Moreover, the present invention relates to the use of the abovementioned nucleic acid sequences, of functional analogs of the SEQ ID NO:3 or SEQ ID NO:7 or of polypeptides encoded by one of the abovementioned nucleic acid sequences in a method for identifying herbicidally active compounds which inhibit serine hydroxymethyltransferases, and to the use of these compounds which have been identified by the method as herbicides.Type: ApplicationFiled: December 4, 2007Publication date: June 26, 2008Applicant: BASF AktiengesellschaftInventors: Uwe SONNEWALD, Frederik BORNKE, Kirsten DEIST, Marc Stitt NIGEL, Wolfgang LEIN, Thomas EHRHARDT, Andreas REINDL, Ralf-Michael SCHMIDT, Annette FREUND
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Patent number: 7374899Abstract: The present invention relates to the use of a polypeptide with the biological activity of a sucrose-6-phosphate phosphatase which, if not present, brings about growth retardation symptoms and chlorotic leaves and which is encoded by the nucleic acid sequences SEQ ID NO:1, SEQ ID NO:3, SEQ ID NO:5 or by a functional equivalent of SEQ ID NO:1, SEQ ID NO:3 or SEQ ID NO:5 as target for herbicides. Moreover, the present invention relates to the use of the abovementioned polypeptides in a method for identifying herbicidal or growth-regulatory compounds which inhibit sucrose-6-phosphate phosphatase. Moreover, the invention relates to the use of these compounds which have been identified via the method as herbicides or growth regulators.Type: GrantFiled: July 16, 2003Date of Patent: May 20, 2008Assignee: BASF AktiengesellschaftInventors: Thomas Ehrhardt, Uwe Sonnewald, Frederik Börnke, Shuai Chen
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Patent number: 7319013Abstract: The present invention relates to serine hydroxymethyltransferase (E.C. 2.1.2.1) as novel target for herbicides, and to nucleic acid sequences encoding a polypeptide with the biological activity of a serine hydroxymethyltransferase, which, when not present, bring about growth retardation symptoms and chlorotic leaves, comprising the nucleic acid sequence SEQ ID No:3, and functional equivalents of the abovementioned nucleic acid sequence or the nucleic acid sequence SEQ ID NO:7 and functional equivalents of the abovementioned nucleic acid sequence. Moreover, the present invention relates to the use of the abovementioned nucleic acid sequences, of functional analogs of the SEQ ID NO:3 or SEQ ID NO:7 or of polypeptides encoded by one of the abovementioned nucleic acid sequences in a method for identifying herbicidally active compounds which inhibit serine hydroxymethyltransferases, and to the use of these compounds which have been identified by the method as herbicides.Type: GrantFiled: March 13, 2003Date of Patent: January 15, 2008Assignee: BASF AktiengesellschaftInventors: Uwe Sonnewald, Frederik Börnke, Kirsten Deist, Marc Stitt Nigel, Wolfgang Lein, Thomas Ehrhardt, Andreas Reindl, Ralf-Michael Schmidt, Annette Freund
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Publication number: 20070256192Abstract: The invention relates to methods for generating or increasing a pathogen resistance in plants by expression, preferably pathogen-inducible expression, of a sucrose isomerase.Type: ApplicationFiled: July 2, 2003Publication date: November 1, 2007Inventors: Karin Herbers, Bettina Tschiersch, Uwe Sonnewald, Frederik Bornke, Horst-Ekkehard Neuhaus
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Publication number: 20070113300Abstract: The present invention relates to Clp-protease, which, when absent, brings about reduced growth and chlorotic leaves as target for herbicides. For this purpose, novel nucleic acid sequences encompassing SEQ ID NO:3, SEQ ID NO:11 and SEQ ID NO: 17 and functional equivalents of SEQ ID NO:3, SEQ ID NO:11 and SEQ ID NO: 17 are provided. Moreover, the present invention relates to the use of Clp-protease in a method for identifying compounds with herbicidal or growth-regulatory activity, and to the use of the compounds identified by this method as herbicides or growth regulators.Type: ApplicationFiled: November 30, 2004Publication date: May 17, 2007Applicant: BASF AktiengesellschaftInventors: Thomas Ehrhardt, Andreas Reindl, Annette Freund, Ralf-Michael Schmidt, Uwe Sonnewald, Marc Nigel, Wolfgang Lein, Frederik Bornke, Kirsten Deist
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Publication number: 20070042451Abstract: The invention relates to the use of glycine decarboxylase complex, which is used as a target for herbicides in the absence of growth retardations and chlorotic leaves. Novel nucleic acid sequences comprising SEQ ID NO:1 and functional equivalents of SEQ ID NO:1 are thus disclosed. The invention also relates to the use of glycine decarboxylase complex and the functional equivalents thereof in a method for identifying compounds having a herbicidal or growth-regulatory effect, in addition to the use of said compounds identified via said method as herbicides or growth regulators.Type: ApplicationFiled: October 27, 2004Publication date: February 22, 2007Applicant: BASF AktiengesellschaftInventors: Thomas Ehrhardt, Andreas Reindl, Annette Freund, Ralf-Michael Schmidt, Uwe Sonnewald, Marc Nigel, Wolfgang Lein, Frederik Bornke, Kirsten Deist
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Publication number: 20070003934Abstract: The present invention relates to the use of 2-methyl-6-solanylbenzoquinone methyltransferase which, when absent, brings about retarded growth and chlorotic leaves, as target for herbicides. In this context, there are provided novel nucleic acid sequences comprising SEQ ID NO:5 and SEQ ID NO:7 and corresponding functional equivalents. Moreover, the present invention relates to the use of 2-methyl-6-solanylbenzoquinone methyltransferase and its functional equivalents in a method for identifying herbicidal or growth-regulatory compounds, and to the use of the compounds identifed via the method as herbicides or growth regulators.Type: ApplicationFiled: November 30, 2004Publication date: January 4, 2007Applicant: BASF AKIENGESELLSCHAFTInventors: Thomas Ehrhardt, Andreas Reindl, Annette Freund, Ralf-Michael Schmidt, Uwe Sonnewald, Marc Nigel, Wolfgang Lein, Frederik Bornke
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Publication number: 20060058190Abstract: The present invention relates to malate dehydrogenase, which, when absent, brings about reduced growth and chlorotic leaves and is encoded by the nucleic acid sequence SEQ ID NO:2 or by a functional equivalent of this nucleic acid sequence, as target for herbicides. For this purpose, novel nucleic acid sequences encompassing SEQ ID NO:2 and functional equivalents of SEQ ID NO:2 are provided. Moreover, the present invention relates to the use of the abovementioned malate dehydrogenase and its functional equivalents in a method for identifying compounds with herbicidal or growth-regulatory activity, and to the use of the compounds identified by this method as herbicides or growth regulators.Type: ApplicationFiled: December 17, 2003Publication date: March 16, 2006Inventors: Thomas Ehrhardt, Andreas Reindl, Annette Freund, Ralf-Michael Schmidt, Kirsten Deist, Uwe Sonnewald, Marc Nigel, Wolfgang Lein, Frederik Bornke
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Publication number: 20060035786Abstract: The present invention relates to the use of a polypeptide with the biological activity of a sucrose-6-phosphate phosphatase which, if not present, brings about growth retardation symptoms and chlorotic leaves and which is encoded by the nucleic acid sequences SEQ ID NO:1, SEQ ID NO:3, SEQ ID NO:5 or by a functional equivalent of SEQ ID NO:1, SEQ ID NO:3 or SEQ ID NO:5 as target for herbicides. Moreover, the present invention relates to the use of the abovementioned polypeptides in a method for identifying herbicidal or growth-regulatory compounds which inhibit sucrose-6-phosphate phosphatase. Moreover, the invention relates to the use of these compounds which have been identified via the method as herbicides or growth regulators.Type: ApplicationFiled: July 16, 2003Publication date: February 16, 2006Applicant: BASF AktiengesellschaftInventors: Thomas Ehrhardt, Uwe Sonnewald, Frederik Bornke, Shuai Chen
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Publication number: 20050251879Abstract: The invention relates to plants and plant cells which have a transient or permanent virus resistance as a result of modulation of the gene expression and/or binding behavior of vegetable DnaJ-like proteins. The invention also relates to methods for the production of transgenic plants with increased virus resistance, wherein the expression of vegetable DnaJ-like proteins which interact with viral components is substantially prevented by silencing the DnaJ-like proteins. The invention further relates to methods for the production of transgenic plants with increased virus resistance, wherein the interaction of viral components with vegetable DnaJ-like proteins is substantially prevented by expression of dominant-negative mutants of the DnaJ-like proteins, by antibodies against DnaJ-like proteins or by specific inhibitors.Type: ApplicationFiled: January 19, 2005Publication date: November 10, 2005Inventors: Daniel Hofius, Frederik Bornke, Uwe Sonnewald
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Publication number: 20050142553Abstract: The present invention relates to serine hydroxymethyltransferase (E.C. 2.1.2.1) as novel target for herbicides, and to nucleic acid sequences encoding a polypeptide with the biological activity of a serine hydroxymethyltransferase, which, when not present, bring about growth retardation symptoms and chlorotic leaves, comprising the nucleic acid sequence SEQ ID No:3, and functional equivalents of the abovementioned nucleic acid sequence or the nucleic acid sequence SEQ ID NO:7 and functional equivalents of the abovementioned nucleic acid sequence. Moreover, the present invention relates to the use of the abovementioned nucleic acid sequences, of functional analogs of the SEQ ID NO:3 or SEQ ID NO:7 or of polypeptides encoded by one of the abovementioned nucleic acid sequences in a method for identifying herbicidally active compounds which inhibit serine hydroxymethyltransferases, and to the use of these compounds which have been identified by the method as herbicides.Type: ApplicationFiled: March 13, 2003Publication date: June 30, 2005Inventors: Uwe Sonnewald, Frederik Bornke, Kirsten Deist, Marc Nigel, Wolfgang Lein, Thomas Ehrhardt, Andreas Reindl, Ralf-Michael Schmidt, Annette Freund
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Publication number: 20030159181Abstract: Methods for influencing pollen development by modifying the sucrose metabolism in transgenic plant cells and plants and generating male sterile plants by sucrose depletion in pollen. An expression of a protein has enzymatic activity of a sucrose isomerase in transgenic plant cells. Nucleic acid molecules contain a DNA sequence encoding a protein having the enzymatic activity of a sucrose isomerase, wherein the DNA sequence is functionally linked with the regulatory sequences of a promoter active in plants so that the DNA sequence is expressed in anthers or pollen. The invention further relates to transgenic plants and plant cells that contain the inventive nucleic acid molecule and whose male plant and plant cells are sterile due to the expression of the DNA sequence that encodes a protein having the enzymatic activity of a sucrose isomerase. The invention also relates to harvest products and the propagation material of said transgenic plants.Type: ApplicationFiled: August 14, 2002Publication date: August 21, 2003Inventors: Frederik Bornke, Uwe Sonnewald