Patents by Inventor Frederik Holst

Frederik Holst has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detection of ESR1 amplification in breast cancer
    Patent number: 8101352
    Abstract: The present invention relates to an in-vitro method of identifying a tumor resulting from a proliferative breast disease as responsive to anti-estrogen treatment. Further, the invention relates to an in-vitro method of identifying a candidate patient with a proliferative breast disease as suitable for anti-estrogen treatment. In a further aspect, the invention provides an in-vitro method of identifying an individual with a non-cancerous proliferative breast disease who is at risk of developing breast cancer. The invention also provides kits for performing the above methods.
    Type: Grant
    Filed: June 26, 2007
    Date of Patent: January 24, 2012
    Assignee: Universitatsklinikum Hamburg-Eppendorf
    Inventors: Guido Sauter, Ronald Simon, Phillip Stahl, Frederik Holst, Khawla Al-Kuraya, Christian Ruiz
  • DETECTION OF ESR1 AMPLIFICATION IN ENDOMETRIUM CANCER AND OVARY CANCER
    Publication number: 20100210612
    Abstract: The present invention relates to an in-vitro method of identifying a tumor resulting from a proliferative disease of the endometrium or ovary as responsive to anti-estrogen treatment. Further, the invention relates to an in-vitro method of identifying a candidate patient with a proliferative disease of the endometrium or ovary as suitable for anti-estrogen treatment. In a further aspect, the invention provides an in-vitro method of identifying an individual with a non-cancerous proliferative disease of the endometrium or ovary who is at risk of developing endometrial or ovarian cancer. The invention also provides kits for performing the above methods.
    Type: Application
    Filed: February 15, 2008
    Publication date: August 19, 2010
    Applicant: UNIVERSITATSKLINIKUM HAMBURG-EPPENDORF
    Inventors: Ronald Simon, Guido Sauter, Luigi Terracciano, Frederik Holst, Annette Lebeau, Andreas Turzynski
  • DETECTION OF ESR1 AMPLIFICATION IN BREAST CANCER
    Publication number: 20100086915
    Abstract: The present invention relates to an in-vitro method of identifying a tumor resulting from a proliferative breast disease as responsive to anti-estrogen treatment. Further, the invention relates to an in-vitro method of identifying a candidate patient with a proliferative breast disease as suitable for anti-estrogen treatment. In a further aspect, the invention provides an in-vitro method of identifying an individual with a non-cancerous proliferative breast disease who is at risk of developing breast cancer. The invention also provides kits for performing the above methods.
    Type: Application
    Filed: June 26, 2007
    Publication date: April 8, 2010
    Applicant: UNIVERSITÄTSKLINIKUM HAMBURGEPPENDORF
    Inventors: Guido Sauter, Ronald Simon, Philip Stahl, Frederik Holst, Khawla A-Kuraya, Christian Ruiz