Abstract: The present invention described a device which comprises: a first container having at least one hole or outlet means present in the bottom and/or sides of the first container; a second container; and a compressor or means to apply pressure where the device is constructed in such a way that it is able to squeeze or compress a sample present in the first container, and hence releases forces or separates fluid from the sample where the first container is constructed in such a way that some or all of the fluid separated from the sample will pass through the hole or outlet into the second container. The device allows the preparation of fluid samples from tissue in a reliable, reproducible inexpensive manner.