Patents by Inventor Frederik Miggelbrink

Frederik Miggelbrink has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the inactivation of amylase in the presence of protease
    Patent number: 7955829
    Abstract: The invention relates to a method for the inactivation of amylase in a solution comprising Rhizomucor miehei aspartic protease by keeping the solution at a pH between 2.1 and 2.8 and at a temperature between 20° C. and 40° C. for a period of time sufficient to inactivate amylase for at least 95%. With this method the level of residual Rhizomucor miehei aspartic protease activity in the solution at the end of the heating time is at least 90%, preferably at least 95%, and the residual amylase activity is 0.05 RAU/g or lower, more preferably 0.001 RAU/g or lower, i.e. more than 99% of the amylase activity has been inactivated.
    Type: Grant
    Filed: December 18, 2002
    Date of Patent: June 7, 2011
    Assignee: DSM IP Assets B.V.
    Inventors: Mylene Caussette, Frederik Miggelbrink, Gregory Maufroid
  • Method for the inactivating of amylase in the presence of protease
    Publication number: 20050064573
    Abstract: The invention relates to a method for the inactivation of amylase in a solution comprising Rhizomucor miehei aspartic protease by keeping the solution at a pH between 2.1 and 2.8 and at a temperature between 20° C. and 40° C. for a period of time sufficient to inactivate amylase for at least 95%. With this method the level of residual Rhizomucor miehei aspartic protease activity in the solution at the end of the heating time is at least 90%, preferably at least 95%, and the residual amylase activity is 0.05 RAU/g or lower, more preferably 0.001 RAU/g or lower, i.e. more than 99% of the amylase activity has been inactivated.
    Type: Application
    Filed: December 18, 2002
    Publication date: March 24, 2005
    Inventors: Mylene Caussette, Frederik Miggelbrink, Gregory Maufroid