Patents by Inventor Fredric E Wondisford

Fredric E Wondisford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODIFIED KISSPEPTIN RECEPTOR AGONISTS FOR FATTY LIVER DISEASE
    Publication number: 20230256051
    Abstract: This invention involves repurposing the use of TAK-448 in NAFLD or NASH. In this study, a diet-induced mouse model of NAFLD was used to demonstrate that a hepatic knock-out of Kiss1r promotes steatosis. Moreover, infusion of the KP analog (TAK-488) in obese, wild-type diabetic mice protects against disease progression. Thus, the present invention provides a therapy for metabolic disorders such as NAFLD and NASH through the administration of TAK-488, a long-lasting synthetic analog of kisspeptin-10, a naturally occurring peptide found in the blood.
    Type: Application
    Filed: April 8, 2021
    Publication date: August 17, 2023
    Inventors: M. Moshmi BHATTACHARYA BABWAH, Andy VIDESH BABWAH, Sally RADOVICK, Fredric E. WONDISFORD
  • Biologically active synthetic thyrotropin and cloned gene for producing same
    Publication number: 20010053538
    Abstract: Substantially pure recombinant TSH has been prepared from a clone comprising complete nucleotide sequence for the expression of the TSH. Diagnostic and therapeutic applications of the synthetic TSH are described.
    Type: Application
    Filed: June 27, 2001
    Publication date: December 20, 2001
    Inventors: Fredric E. Wondisford, Bruce D. Weintraub
  • Biologically active synthetic thyrotropin and cloned gene for producing same
    Patent number: 6284491
    Abstract: Substantially pure recombinant TSH has been prepared from a clone comprising complete nucleotide sequence for the expression of the TSH. Diagnostic and therapeutic applications of the synthetic TSH are described.
    Type: Grant
    Filed: May 11, 2000
    Date of Patent: September 4, 2001
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Fredric E Wondisford, Bruce D. Weintraub
  • Biologically active synthetic thyrotropin and cloned gene producing same
    Patent number: 6117991
    Abstract: Substantially pure recombinant TSH has been prepared from a clone comprising complete nucleotide sequence for the expression of the TSH. Diagnostic and therapeutic applications of the synthetic TSH are described.
    Type: Grant
    Filed: September 22, 1994
    Date of Patent: September 12, 2000
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Fredric E Wondisford, Bruce D. Weintraub