Patents by Inventor Fredric Gorin

Fredric Gorin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of intracellular urokinase plasminogen activator and methods of use thereof
    Patent number: 8546322
    Abstract: The present invention provides compositions comprising amiloride amino acid and peptide conjugates. Efficient methods are also provided for administering the compositions for treating cancer and for delivering an amiloride conjugate into cancer cells in a subject in need thereof.
    Type: Grant
    Filed: August 1, 2008
    Date of Patent: October 1, 2013
    Assignee: The Regents of the University of California
    Inventors: Fredric A. Gorin, Michael H. Nantz
  • INHIBITORS OF INTRACELLULAR UROKINASE PLASMINOGEN ACTIVATOR AND METHODS OF USE THEREOF
    Publication number: 20120108494
    Abstract: The present invention provides compositions comprising amiloride amino acid and peptide conjugates. Efficient methods are also provided for administering the compositions for treating cancer and for delivering an amiloride conjugate into cancer cells in a subject in need thereof.
    Type: Application
    Filed: August 1, 2008
    Publication date: May 3, 2012
    Applicant: The Regents of the University of California
    Inventors: Fredric A. Gorin, Michael H. Nantz
  • AMINO ACID AND PEPTIDE CONJUGATES OF AMILORIDE AND METHODS OF USE THEREOF
    Publication number: 20110195907
    Abstract: The present invention provides compositions comprising amiloride amino acid and peptide conjugates. Efficient methods are also provided for administering the amiloride conjugates of the present invention for treating cancer or a central nervous system disease or disorder or for preventing or reducing ischemia-reperfusion injury. Further, kits are provided for the treatment of a central nervous system disease or disorder or for the prevention or reduction of ischemia-reperfusion injury using the amiloride conjugates of the present invention.
    Type: Application
    Filed: January 3, 2011
    Publication date: August 11, 2011
    Applicant: The Regents of the University of California Office of Technology Transfer
    Inventors: Fredric A. Gorin, Michael H. Nantz
  • Amino acid and peptide conjugates of amiloride and methods of use thereof
    Patent number: 7863415
    Abstract: The present invention provides compositions comprising amiloride amino acid and peptide conjugates. Efficient methods are also provided for administering the amiloride conjugates of the present invention for treating cancer or a central nervous system disease or disorder or for preventing or reducing ischemia-reperfusion injury. Further, kits are provided for the treatment of a central nervous system disease or disorder or for the prevention or reduction of ischemia-reperfusion injury using the amiloride conjugates of the present invention.
    Type: Grant
    Filed: January 21, 2005
    Date of Patent: January 4, 2011
    Assignee: The Regents of the University of California
    Inventors: Fredric A. Gorin, Michael H. Nantz
  • Amino acid and peptide conjugates of amiloride and methods of use thereof
    Publication number: 20060160746
    Abstract: The present invention provides compositions comprising amiloride amino acid and peptide conjugates. Efficient methods are also provided for administering the amiloride conjugates of the present invention for treating cancer or a central nervous system disease or disorder or for preventing or reducing ischemia-reperfusion injury. Further, kits are provided for the treatment of a central nervous system disease or disorder or for the prevention or reduction of ischemia-reperfusion injury using the amiloride conjugates of the present invention.
    Type: Application
    Filed: January 21, 2005
    Publication date: July 20, 2006
    Applicant: The Regents of the University of California
    Inventors: Fredric Gorin, Michael Nantz
  • Brain glycogen phosphorylase cancer antigen
    Patent number: 6096520
    Abstract: The invention describes brain glycogen phosphorylase tumor rejection antigen precursors, including nucleic acids encoding such tumor rejection antigen precursors, tumor rejection antigen peptides or precursors thereof and antibodies relating thereto. Methods and products also are provided for diagnosing and treating conditions characterized by expression of a brain glycogen phosphorylase tumor rejection antigen or precursor thereof.
    Type: Grant
    Filed: December 18, 1998
    Date of Patent: August 1, 2000
    Assignees: Ludwig Institute for Cancer Research, The Regents of the University of California
    Inventors: Vincent Brichard, Aline van Pel, Thierry Boon-Falleur, Fredric A. Gorin