Patents by Inventor Fredric John LIM

Fredric John LIM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYSTEMS AND METHODS FOR PRODUCING PHARMACEUTICAL COMPOSITIONS USING PERISTALTIC PUMPS AND DAMPENERS
    Publication number: 20230390485
    Abstract: Provided herein are methods and systems for use with peristaltic pumps. More particularly, provided herein are peristaltic pump systems that include a dampener for reducing the pulsations of the flowrate from the peristaltic pump system to produce, mix, transfer and/or manufacture pharmaceutical compositions and formulations, including pharmaceutical compositions and formulations comprising lipids and RNA.
    Type: Application
    Filed: March 7, 2023
    Publication date: December 7, 2023
    Inventors: Robert Daniel OVADIA, Christopher Andrew Petry, Fredric John Lim, Heinrich Haas, Sebastian Hoerner, Ferdia Bates, Tobias Kind, Peer Andre Berger
  • RAPID DEPRESSURIZATION CONTROLLED ICE NUCLEATION IN PHARMACEUTICAL FREEZE-DRYING
    Publication number: 20220397346
    Abstract: A lyophilization method for lyophilizing products inside one or more vials within a lyophilization chamber is disclosed which includes humidifying a charge gas to a predetermined relative humidity, cooling shelves in the lyophilization chamber to a predetermined temperature, pressurizing the chamber with the humidified charge gas to a pressurization threshold to thereby achieving a target relative humidity level within the lyophilization chamber, and suddenly releasing pressure within the lyophilization chamber until a depressurization threshold is reached in a short time interval up to about 4 seconds, during the depressurization, product inside one or more vials nucleate.
    Type: Application
    Filed: June 3, 2022
    Publication date: December 15, 2022
    Applicants: Purdue Research Foundation, Genentech, Inc.
    Inventors: Andrew Strongrich, Alina Alexeenko, Fredric John Lim, Lokesh Kumar
  • METHODS AND FORMULATIONS FOR REDUCING RECONSTITUTION TIME OF LYOPHILIZED POLYPEPTIDES
    Publication number: 20220298263
    Abstract: The present invention relates to methods and formulations useful for reducing the reconstitution time of lyophilized polypeptides.
    Type: Application
    Filed: June 3, 2022
    Publication date: September 22, 2022
    Applicant: Genentech, Inc.
    Inventors: Fredric John LIM, Jacob Edward LUOMA, Isidro Angelo Eleazar ZARRAGA, Christopher Michael HEYNES
  • Methods and formulations for reducing reconstitution time of lyophilized polypeptides
    Patent number: 11377505
    Abstract: The present invention relates to methods and formulations useful for reducing the reconstitution time of lyophilized polypeptides.
    Type: Grant
    Filed: May 23, 2019
    Date of Patent: July 5, 2022
    Assignee: Genentech, Inc.
    Inventors: Fredric John Lim, Jacob Edward Luoma, Isidro Angelo Eleazar Zarraga, Christopher Michael Heynes
  • METHODS AND FORMULATIONS FOR REDUCING RECONSTITUTION TIME OF LYOPHILIZED POLYPEPTIDES
    Publication number: 20190389974
    Abstract: The present invention relates to methods and formulations useful for reducing the reconstitution time of lyophilized polypeptides.
    Type: Application
    Filed: May 23, 2019
    Publication date: December 26, 2019
    Applicant: Genentech, Inc.
    Inventors: Fredric John LIM, Jacob Edward LUOMA, Isidro Angelo Eleazar ZARRAGA, Christopher Michael HEYNES