Abstract: A shaft assembly is disclosed which comprises an end effector configurable in an open configuration and a closed configuration, a closure system configured to transition the end effector toward the closed configuration during a closure stroke, a firing member movable through a firing stroke, and a frame. In various instances, the shaft assembly comprises a first bailout configured to shift the frame in order to open the end effector and a second, independent, bailout configured to retract the firing member during and/or after the firing stroke. In certain instances, the closure system is expandable to perform the closure stroke. In at least one such instance, the closure system comprises a proximal portion mounted to the frame and a distal portion movable relative to the proximal portion. In at least one instance, the firing member engages the closure member to expand the closure system.

Abstract: A shaft assembly is disclosed which comprises an end effector configurable in an open configuration and a closed configuration, a closure system configured to transition the end effector toward the closed configuration during a closure stroke, a firing member movable through a firing stroke, and a frame. In various instances, the shaft assembly comprises a first bailout configured to shift the frame in order to open the end effector and a second, independent, bailout configured to retract the firing member during and/or after the firing stroke. In certain instances, the closure system is expandable to perform the closure stroke. In at least one such instance, the closure system comprises a proximal portion mounted to the frame and a distal portion movable relative to the proximal portion. In at least one instance, the firing member engages the closure member to expand the closure system.

Abstract: An exemplary anastomosis device comprises a proximal ring, a distal ring, and a middle ring. The middle ring has apertures configured to communicate a fluid such as an adhesive. The exemplary anastomosis device also has arms joining the proximal ring to the center member and arms joining the distal ring to the center member. The anastomosis device is configured to move from an unactuated position, where it has a generally cylindraceous configuration, to an actuated position, where it has a generally rivet-like configuration. The anastomosis device may be used to provide and secure an anastomosis between adjacent tissue walls. Adhesive may be communicated through the apertures of the middle ring of the anastomosis device to seal or strengthen the anastomosis. An applier may be used to deploy the anastomosis device and to communicate the adhesive through the apertures.

Abstract: An apparatus for forming a gastric restriction comprises an applier, an expandable member, and an adhesive. The applier comprises an elongate shaft, and is dimensioned to fit in an esophagus. The applier has a conduit configured to communicate a fluid medium. The expandable member is in fluid communication with the conduit of the applier. The adhesive is positioned on at least a portion of the outer surface of the expandable member. The adhesive is configured to adhere the expanded expandable member to the inner wall of a patient's stomach. The expandable member may have a generally toroid configuration with a stoma, such that the expandable member may provide a gastric restriction when expanded and adhered to the inner wall of a patient's stomach. The expandable member may thus provide a treatment for morbid obesity by reducing food intake, by reducing stomach volume, or otherwise.

Abstract: A system for dispensing an adhesive comprises a first dispenser, a second dispenser, and a conduit. The first dispenser contains an adhesive. The second dispenser comprises a fluid. The first dispenser and second dispenser are each in fluid communication with the conduit. The conduit has an opening. One or both of the first dispenser or the second dispenser is operable to dispense adhesive or fluid through the opening of the conduit. The system may be used to apply adhesive to the tissue of a patient in a precise and controlled manner.

Abstract: A system for creating an invaginated portion in a stomach comprises a suction device and a securing member. The suction device comprises a suction head operable to provide suction, a shaft connected to the suction head, and a vacuum lumen in fluid communication with the suction head. The suction head and vacuum lumen are operable to induce a vacuum adjacent to tissue. The suction device is further operable to create an invaginated portion with the tissue. The securing member is operable to substantially maintain the configuration of the invaginated portion of tissue. The suction device may comprise gripping jaw members having teeth. The securing member may comprise an adhesive and/or sutures and the like. The system may be used to create invaginated portions within a stomach. Such invaginated portions may reduce stomach volume to address obesity or other conditions.

Abstract: An exemplary adhesive applier comprises a handle portion, a shaft portion, and a tip portion. The handle portion is configured to be gripped by a user. The shaft portion is in communication with the handle portion. The tip portion is in communication with the shaft portion. The tip portion is operable to articulate relative to the shaft portion in response to user input, and is operable to dispense a liquid substance at a plurality of articulated positions. In some embodiments, the handle portion is configured to pivot relative to the shaft portion, and the tip portion is operable to pivot relative to the shaft portion in response to pivoting of the handle portion relative to the shaft portion.

Abstract: An apparatus for applying a liquid substance comprises a bulb portion, a cannulated shaft in fluid communication with the bulb portion, and a swab portion in fluid communication with the cannulated shaft. The bulb portion comprises a capsule. The capsule comprises a liquid substance. The bulb portion further comprises a valve operable to control the flow of a medium through the bulb portion. The bulb portion is operable to rupture the capsule to release the liquid substance. The cannulated shaft is dimensioned to extend percutaneously into a patient. The swab portion is operable to apply the liquid substance. The apparatus may be used to percutaneously apply adhesives to tissue, such as through a trocar or other cannulated member.