Patents by Inventor Fredrik Lundstrom
Fredrik Lundstrom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11717790Abstract: A method includes measuring, by a flow sensor (70), a flow rate of a permeate fluid (48) flowing through a filter (20) of a membrane filtration system (12). Further, the method includes receiving, by a control unit (86), the measured flow rate of the permeate fluid (48) and determining, by the control unit (86), a first flux rate of the filter (20) based on the measured flow rate of the permeate fluid (48). Furthermore, the method includes comparing, by the control unit (86), the determined first flux rate with a first predetermined flux rate. Additionally, the method includes operating the membrane filtration system (12), by the control unit (86), in a normal mode or a flux tolerant mode based on the comparison of the determined first flux rate with the first predetermined flux rate. The flux tolerant mode of the membrane filtration system (12) is further based on a determined normalized water permeability value of the filter (20).Type: GrantFiled: June 20, 2019Date of Patent: August 8, 2023Assignee: CYTIVA SWEDEN ABInventors: Nityananda Maiya, Deepak Aravind, Fredrik Lundström, Saameera Simha Hindupur, Shivakumar Selvaraj, Alagur Sahebagouda
-
Publication number: 20230193188Abstract: A bioprocessing system (100, 200) including a storage unit (102, 202) for storing a feed fluid (103, 203), a filter (106, 206) coupled to the storage unit (102, 202) via a feed path (104, 204), and a feed pump (114, 212) coupled to the feed path (104, 204). The bioprocessing system (100, 200) further includes a collection unit (102, 216) coupled to the filter (106, 206) via a downstream path (118, 218) and a turbidity sensor (134, 224) coupled to the downstream path (118, 218). Furthermore, the bioprocessing system (100, 200) includes a processing unit (136, 226) configured to receive an output from the turbidity sensor (134, 224) and determine a concentration of a product in a filtration fluid (121, 222) based on the output. The processing unit (136, 226) is further configured to monitor an operating condition of the filter (106, 206) on-line based on concentration of the product.Type: ApplicationFiled: June 24, 2021Publication date: June 22, 2023Inventors: Shivakumar SELVARAJ, Sahebagouda ALAGUR, Sameera Simha HINDUPUR, Nityananda MAIYA, Mayank DADHWAL, Fredrik LUNDSTROM
-
Publication number: 20230141350Abstract: A base station (1) and a bioprocess system (3), wherein said base station (1) comprises: a frame or housing (5), wherein said frame or housing comprises a number of valves (7a-f, 9a-d, 11a-f, 13a-e, 15a-f) into which a disposable tubing set (21) during run of the system is provided such that at least one inlet (23a-j) of the disposable tubing set is connected to at least one outlet (25a-f) of the disposable tubing set via a bioprocess separation device (31) of the bioprocess system (3); and a movable pump holding device (35), which can be provided in at least two different positions, whereof one is within the frame or housing (5) and another is at least partly outside the frame or housing (5) and which comprises at least one pump main body (37), said pump main body comprising a connection (39) configured for connecting to a disposable pump connection part (27) comprised in the disposable tubing set (21).Type: ApplicationFiled: December 29, 2022Publication date: May 11, 2023Inventors: Anna Karlin, Jan-Erik Lynga, Mike Peters, Fredrik Lundstrom, Mats Rimmo
-
Patent number: 11565196Abstract: A base station (1) and a bioprocess system (3), wherein said base station (1) comprises: a frame or housing (5), wherein said frame or housing comprises a number of valves (7a-f, 9a-d, 11a-f, 13a-e, 15a-f) into which a disposable tubing set (21) during run of the system is provided such that at least one inlet (23a-j) of the disposable tubing set is connected to at least one outlet (25a-f) of the disposable tubing set via a bioprocess separation device (31) of the bioprocess system (3); a movable pump holding device (35), which can be provided in at least two different positions, whereof one is within the frame or housing (5) and another is at least partly outside the frame or housing (5) and which comprises at least one pump main body (37), said pump mainbody comprising a connection (39) configured for connecting to a disposable pump connection part (27) comprised in the disposable tubing set (21).Type: GrantFiled: October 25, 2018Date of Patent: January 31, 2023Assignee: Cytiva Sweden ABInventors: Anna Karlin, Jan-Erik Lynga, Mike Peters, Fredrik Lundstrom, Mats Rimmo
-
Patent number: 11466241Abstract: The invention discloses a first unit (1) for treatment of a bioprocess liquid comprising a first lateral face (2), a second lateral face (3) and a front face (4) which meets the two said lateral faces. The front face comprises: a plurality of valves (7) adapted to receive and act upon one or more legs (8) of a disposable flow path (6); optionally one or more pumps (10) adapted to receive and act upon one or more legs of the disposable flow path; optionally one or more sensors (11) adapted to receive and to measure one or more parameters in one or more legs of the disposable flow path; wherein the plurality of valves and optional pumps and sensors are vertically offset from each other to give one or more legs of a disposable flow path received by said valves and optional pumps and sensors a slope of at least 3.0 degrees from the horizontal plane (h).Type: GrantFiled: November 25, 2016Date of Patent: October 11, 2022Assignee: Cytiva Sweden ABInventors: Amit Kumar Singh, Klaus Gebauer, Supti Datta, Jakob Liderfelt, Nachiket Karmarkar, Ajit S. Vernekar, Mats Olsson, Rajan Thiyaga, Amit K. Sharma, Sasi Kumar Nutalapati, Fredrik Lundstrom, Jean Pierre Neff
-
Publication number: 20210260530Abstract: A method includes measuring, by a flow sensor (70), a flow rate of a permeate fluid (48) flowing through a filter (20) of a membrane filtration system (12). Further, the method includes receiving, by a control unit (86), the measured flow rate of the permeate fluid (48) and determining, by the control unit (86), a first flux rate of the filter (20) based on the measured flow rate of the permeate fluid (48). Furthermore, the method includes comparing, by the control unit (86), the determined first flux rate with a first predetermined flux rate. Additionally, the method includes operating the membrane filtration system (12), by the control unit (86), in a normal mode or a flux tolerant mode based on the comparison of the determined first flux rate with the first predetermined flux rate. The flux tolerant mode of the membrane filtration system (12) is further based on a determined normalized water permeability value of the filter (20).Type: ApplicationFiled: June 20, 2019Publication date: August 26, 2021Inventors: Nityananda Maiya, Deepak Aravind, Fredrik Lundström, Saameera Simha Hindupur, Shivakumar Selvaraj, Alagur Sahebagouda
-
Publication number: 20210162317Abstract: A connection device (1; 101) configured for connecting a separation system (3) with a separation device (5), wherein a fluid can be flowed from a separation system outlet connection (19), through a bypass fluid path (27) of the connection device to the separation system inlet connection (15) while a connected separation device (5) is by passed. For achieving this at least one of an inlet and an outlet valve (31, 33) provided in the connection device is provided in a closed state and at least one bypass valve (35, 35a, 35b) provided in the connection device is provided in an open state.Type: ApplicationFiled: August 20, 2019Publication date: June 3, 2021Inventors: Klaus Gebauer, Andreas Lundin, Fredrik Lundström
-
Publication number: 20210093983Abstract: A base station (1) and a bioprocess system (3), wherein said base station (1) comprises: a frame or housing (5), wherein said frame or housing comprises a number of valves (7a-f, 9a-d, 11a-f, 13a-e, 15a-f) into which a disposable tubing set (21) during run of the system is provided such that at least one inlet (23a-j) of the disposable tubing set is connected to at least one outlet (25a-f) of the disposable tubing set via a bioprocess separation device (31) of the bioprocess system (3); a movable pump holding device (35), which can be provided in at least two different positions, whereof one is within the frame or housing (5) and another is at least partly outside the frame or housing (5) and which comprises at least one pump main body (37), said pump mainbody comprising a connection (39) configured for connecting to a disposable pump connection part (27) comprised in the disposable tubing set (21).Type: ApplicationFiled: October 25, 2018Publication date: April 1, 2021Inventors: Anna Karlin, Jan-Erik Lynga, Mike Peters, Fredrik Lundstrom, Mats Rimmo
-
Publication number: 20210017482Abstract: The invention discloses a first unit (1) for treatment of a bioprocess liquid comprising a first lateral face (2), a second lateral face (3) and a front face (4) which meets the two said lateral faces. The front face comprises: a plurality of valves (7) adapted to receive and act upon one or more legs (8) of a disposable flow path (6); optionally one or more pumps (10) adapted to receive and act upon one or more legs of the disposable flow path; optionally one or more sensors (11) adapted to receive and to measure one or more parameters in one or more legs of the disposable flow path; wherein the plurality of valves and optional pumps and sensors are vertically offset from each other to give one or more legs of a disposable flow path received by said valves and optional pumps and sensors a slope of at least 3.0 degrees from the horizontal plane (h).Type: ApplicationFiled: November 25, 2016Publication date: January 21, 2021Inventors: Amit Kumar Singh, Klaus Gebauer, Supti Datta, Jakob Liderfelt, Nachiket Karmarkar, Ajit S. Vernekar, Mats Olsson, Thiyaga Rajan, Amit K. Sharma, Sasi Kumar Nutalapati, Fredrik Lundstrom, Jean Pierre Neff