Patents by Inventor Fredrik Thoren

Fredrik Thoren has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of PARP-1 inhibitors for protecting tumorcidal lymphocytes from apoptosis
    Publication number: 20060079510
    Abstract: Method and composition for protecting tumorcidal lymphocytes including cytotoxic lymphocytes and NK cells from apoptosis and down regulation are provided. The method and composition include the administration of an effective amount of a PARP-1 inhibitor to a population of cytotoxic T lymphocytes and NK cells in the presence of monocytes or macrophages. In some embodiments, the method and composition additionally include the administration of a reactive oxygen metabolite (ROM) production or release inhibitory compound. Methods of treating cancer, viral diseases, and inflammatory diseases with a PARP-1 inhibitor are likewise provided.
    Type: Application
    Filed: September 29, 2005
    Publication date: April 13, 2006
    Inventors: Kristoffer Hellstrand, Svante Hermodsson, Fredrik Thoren, Ana Romero