Patents by Inventor Fredrik Zetterberg
Fredrik Zetterberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240309038Abstract: A D-galactopyranose compound of formula (1) wherein the pyranose ring is beta-D-galactopyranose, and these compounds are high affinity galectin-3 inhibitors for use in treatment of disorders relating to the binding of a galectin-3 to a ligand in a mammal.Type: ApplicationFiled: December 22, 2021Publication date: September 19, 2024Applicant: GALECTO BIOTECH ABInventors: Fredrik ZETTERBERG, Kristoffer PETERSON, Ulf NILSSON
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Publication number: 20240287122Abstract: D-galactopyranose compound of formula (1) wherein the pyranose ring is ?-D-galactopyranose, and these compounds are high affinity galectin-1 and/or galectin 3 inhibitors for use in treatment of inflammation; fibrosis; scarring; keloid formation; aberrant scar formation; surgical adhesions; septic shock; cancer; metastasising cancers; autoimmune diseases, metabolic disorders; heart disease; heart failure; pathological angiogenesis; eye diseases; atherosclerosis; metabolic diseases; diabetes type I; diabetes type II; insulin resistance; Diastolic heart failure; asthma; and liver disorders.Type: ApplicationFiled: December 20, 2021Publication date: August 29, 2024Applicant: GALECTO BIOTECH ABInventors: Fredrik ZETTERBERG, Kristoffer PETERSON
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Publication number: 20240132531Abstract: A D-galactopyranose compound of formula (1) wherein the pyranose ring is beta-D-galactopyranose, and these compounds are high affinity galectin-1 and/or 3 inhibitors for use in treatment of a disorder relating to the binding of a galectin-1 and/or 3 to a ligand in a mammal.Type: ApplicationFiled: December 21, 2021Publication date: April 25, 2024Applicant: GALECTO BIOTECH ABInventors: Fredrik ZETTERBERG, Kristoffer PETERSON
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Patent number: 11939349Abstract: A compound of the general formula (1). The compound of formula (1) is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Also, a method for treatment of a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human.Type: GrantFiled: July 20, 2022Date of Patent: March 26, 2024Assignee: GALECTO BIOTECH ABInventors: Fredrik Zetterberg, Kristoffer Peterson, Karl Jansson
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Patent number: 11919921Abstract: An embodiment of the present invention relates to a compound of the general formula. The compound of formula is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Furthermore an embodiment of the present invention concerns a method for treatment of a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human.Type: GrantFiled: May 19, 2022Date of Patent: March 5, 2024Assignee: GALECTO BIOTECH ABInventors: Thomas Brimert, Richard Johnsson, Hakon Leffler, Ulf Nilsson, Fredrik Zetterberg
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Publication number: 20240059728Abstract: A D-galactopyranose compound of formula (1) wherein the pyranose ring is beta-D-galactopyranose, and these compounds are high affinity galectin-1 and/or 3 inhibitors for use in treatment of inflammation; fibrosis; scarring; keloid formation; aberrant scar formation; surgical adhesions; scleroderma; systemic sclerosis; septic shock; cancer; metastasising cancers; autoimmune diseases; metabolic disorders; heart disease; heart failure; aortic stenosis; atherosclerosis; pathological angiogenesis; eye diseases; metabolic diseases; insulin resistance; obesity; Diastolic HF; asthma; otosclerosis; mesothelioma; liver disorders Liver cancer; cholangiocarcinoma; biliary tract cancer; and neurodegenerative disorders.Type: ApplicationFiled: February 7, 2022Publication date: February 22, 2024Applicant: GALECTO BIOTECH ABInventors: Kristoffer PETERSON, Fredrik ZETTERBERG, Ulf NILSSON
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Patent number: 11827666Abstract: An ?-D-galactopyranose compound of the general formula (1). The ?-D-galactopyranose compound of formula (1) is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-1 to a ligand in a mammal, such as a human. Furthermore, a method for treatment of a disorder relating to the binding of a galectin, such as galectin-1 to a ligand in a mammal, such as a human.Type: GrantFiled: May 24, 2021Date of Patent: November 28, 2023Assignee: GALECTO BIOTECH ABInventor: Fredrik Zetterberg
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Publication number: 20230063538Abstract: A process for preparing a compound of formula (I) wherein the process is suitable for large scale synthesis. The process includes the consecutive steps of a) reacting a compound of formula IX and a catalyst and optionally adding a base in an organic solvent and optional adding a basic fluoride source agent under suitable conditions to obtain a compound of formula X and b) removing the protective groups of the compound X to obtain the compound formula (I).Type: ApplicationFiled: December 16, 2020Publication date: March 2, 2023Applicant: GALECTO BIOTECH ABInventors: Lise GRAVELLE, Fredrik ZETTERBERG, Andrew TYRRELL, Christine KINNAERT, Alexander WEYMOUTH-WILSON, Robert CLARKSON
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Publication number: 20230014870Abstract: The present invention relates to a D-galactopyranose compound of formula (1) wherein the pyranose ring is ?-D-galactopyranose, and these compounds are high affinity galectin-1 and/or galectin 3 inhibitors for use in treatment of inflammation; fibrosis; scarring; keloid formation; aberrant scar formation; surgical adhesions; septic shock; cancer; metastasising cancers; autoimmune diseases, metabolic disorders; heart disease; heart failure; pathological angiogenesis; eye diseases; atherosclerosis; metabolic diseases; diabetes type I; diabetes type II; insulin resistance; Diastolic heart failure; asthma; liver disorders.Type: ApplicationFiled: July 3, 2020Publication date: January 19, 2023Applicant: GALECTO BIOTECH ABInventor: Fredrik ZETTERBERG
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Publication number: 20220380401Abstract: A compound of the general formula (1). The compound of formula (1) is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Also, a method for treatment of a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human.Type: ApplicationFiled: July 20, 2022Publication date: December 1, 2022Applicant: GALECTO BIOTECH ABInventors: Fredrik ZETTERBERG, Kristoffer PETERSON, Karl JANSSON
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Patent number: 11447517Abstract: A compound of the general formula (1). The compound of formula (1) is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Also, a method for treatment of a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human.Type: GrantFiled: November 15, 2019Date of Patent: September 20, 2022Assignee: GALECTO BIOTECH ABInventors: Fredrik Zetterberg, Kristoffer Peterson, Karl Jansson
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Publication number: 20220289783Abstract: An embodiment of the present invention relates to a compound of the general formula. The compound of formula is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Furthermore an embodiment of the present invention concerns a method for treatment of a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human.Type: ApplicationFiled: May 19, 2022Publication date: September 15, 2022Applicant: Galecto Biotech ABInventors: Thomas BRIMERT, Richard JOHNSSON, Hakon LEFFLER, Ulf NILSSON, Fredrik ZETTERBERG
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Publication number: 20220281909Abstract: A D-galactopyranose compound of formula (1) wherein the pyranose ring is ?-D-galactopyranose, and these compounds are high affinity galectin-3 inhibitors. Also, pharmaceutical compositions including these compounds. Further, a method for treatment of a disorder relating to the binding of a galectin-3 to a ligand, such as inflammation, in a mammal, such as a human, wherein a therapeutically effective amount of at least one of these compounds is administered to a mammal in need of the treatment.Type: ApplicationFiled: July 3, 2020Publication date: September 8, 2022Applicant: GALECTO BIOTECH ABInventors: Fredrik ZETTERBERG, Kristoffer PETERSON
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Publication number: 20220259251Abstract: A D-galactopyranose compound of formula (1) wherein, the pyranose ring is beta-D-galactopyranose, and pharmaceutical composition including these compounds. These are high affinity galectin-1 and/or 3 inhibitors. Also, methods for treating a disorder relating to the binding of a galectin-1 and/or -3 to a ligand in which these compounds or pharmaceutical compositions are administered.Type: ApplicationFiled: July 3, 2020Publication date: August 18, 2022Applicant: GALECTO BIOTECH ABInventor: Fredrik ZETTERBERG
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Publication number: 20220251132Abstract: The present invention relates to a process for preparing a compound of formula (I) wherein said process is suitable for large scale synthesis.Type: ApplicationFiled: June 24, 2020Publication date: August 11, 2022Applicant: GALECTO BIOTECH ABInventors: Fredrik ZETTERBERG, Andrew TYRELL, Ulf NILSSON, Anders BERGH, Jonathan CUMMINS, Alexander WEYMOUTH-WILSON, Robert CLARKSON
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Patent number: 11377464Abstract: An embodiment of the present invention relates to a compound of the general formula. The compound of formula is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Furthermore an embodiment of the present invention concerns a method for treatment of a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human.Type: GrantFiled: September 11, 2020Date of Patent: July 5, 2022Assignee: Galecto Biotech ABInventors: Thomas Brimert, Richard Johnsson, Hakon Leffler, Ulf Nilsson, Fredrik Zetterberg
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Publication number: 20220017558Abstract: A compound of the general formula (1). The compound of formula (1) is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Also, a method for treatment of a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human.Type: ApplicationFiled: November 15, 2019Publication date: January 20, 2022Applicant: GALECTO BIOTECH ABInventors: Fredrik ZETTERBERG, Kristoffer PETERSON, Karl JANSSON
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Publication number: 20210380623Abstract: A prodrug compound of the general formula I or II. The prodrug compound of formula I or II is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Also, a method for treatment of a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human.Type: ApplicationFiled: October 9, 2019Publication date: December 9, 2021Applicant: GALECTO BIOTECH ABInventors: Fredrik ZETTERBERG, Ulf NILSSON
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Publication number: 20210380624Abstract: A compound of the general formula I or II. The compound of formula I or II is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Furthermore, a method for treatment of a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human.Type: ApplicationFiled: October 9, 2019Publication date: December 9, 2021Applicant: GALECTO BIOTECH ABInventors: Fredrik ZETTERBERG, Ulf NILSSON, Thomas BRIMERT, Kristoffer PETERSON, Karl JANSSON
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Publication number: 20210284678Abstract: An ?-D-galactopyranose compound of the general formula (1). The ?-D-galactopyranose compound of formula (1) is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-1 to a ligand in a mammal, such as a human. Furthermore, a method for treatment of a disorder relating to the binding of a galectin, such as galectin-1 to a ligand in a mammal, such as a human.Type: ApplicationFiled: May 24, 2021Publication date: September 16, 2021Applicant: GALECTO BIOTECH ABInventor: Fredrik ZETTERBERG