Patents by Inventor Fredrik Zetterberg

Fredrik Zetterberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240132531
    Abstract: A D-galactopyranose compound of formula (1) wherein the pyranose ring is beta-D-galactopyranose, and these compounds are high affinity galectin-1 and/or 3 inhibitors for use in treatment of a disorder relating to the binding of a galectin-1 and/or 3 to a ligand in a mammal.
    Type: Application
    Filed: December 21, 2021
    Publication date: April 25, 2024
    Applicant: GALECTO BIOTECH AB
    Inventors: Fredrik ZETTERBERG, Kristoffer PETERSON
  • Patent number: 11939349
    Abstract: A compound of the general formula (1). The compound of formula (1) is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Also, a method for treatment of a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human.
    Type: Grant
    Filed: July 20, 2022
    Date of Patent: March 26, 2024
    Assignee: GALECTO BIOTECH AB
    Inventors: Fredrik Zetterberg, Kristoffer Peterson, Karl Jansson
  • Patent number: 11919921
    Abstract: An embodiment of the present invention relates to a compound of the general formula. The compound of formula is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Furthermore an embodiment of the present invention concerns a method for treatment of a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human.
    Type: Grant
    Filed: May 19, 2022
    Date of Patent: March 5, 2024
    Assignee: GALECTO BIOTECH AB
    Inventors: Thomas Brimert, Richard Johnsson, Hakon Leffler, Ulf Nilsson, Fredrik Zetterberg
  • Publication number: 20240059728
    Abstract: A D-galactopyranose compound of formula (1) wherein the pyranose ring is beta-D-galactopyranose, and these compounds are high affinity galectin-1 and/or 3 inhibitors for use in treatment of inflammation; fibrosis; scarring; keloid formation; aberrant scar formation; surgical adhesions; scleroderma; systemic sclerosis; septic shock; cancer; metastasising cancers; autoimmune diseases; metabolic disorders; heart disease; heart failure; aortic stenosis; atherosclerosis; pathological angiogenesis; eye diseases; metabolic diseases; insulin resistance; obesity; Diastolic HF; asthma; otosclerosis; mesothelioma; liver disorders Liver cancer; cholangiocarcinoma; biliary tract cancer; and neurodegenerative disorders.
    Type: Application
    Filed: February 7, 2022
    Publication date: February 22, 2024
    Applicant: GALECTO BIOTECH AB
    Inventors: Kristoffer PETERSON, Fredrik ZETTERBERG, Ulf NILSSON
  • Patent number: 11827666
    Abstract: An ?-D-galactopyranose compound of the general formula (1). The ?-D-galactopyranose compound of formula (1) is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-1 to a ligand in a mammal, such as a human. Furthermore, a method for treatment of a disorder relating to the binding of a galectin, such as galectin-1 to a ligand in a mammal, such as a human.
    Type: Grant
    Filed: May 24, 2021
    Date of Patent: November 28, 2023
    Assignee: GALECTO BIOTECH AB
    Inventor: Fredrik Zetterberg
  • Publication number: 20230063538
    Abstract: A process for preparing a compound of formula (I) wherein the process is suitable for large scale synthesis. The process includes the consecutive steps of a) reacting a compound of formula IX and a catalyst and optionally adding a base in an organic solvent and optional adding a basic fluoride source agent under suitable conditions to obtain a compound of formula X and b) removing the protective groups of the compound X to obtain the compound formula (I).
    Type: Application
    Filed: December 16, 2020
    Publication date: March 2, 2023
    Applicant: GALECTO BIOTECH AB
    Inventors: Lise GRAVELLE, Fredrik ZETTERBERG, Andrew TYRRELL, Christine KINNAERT, Alexander WEYMOUTH-WILSON, Robert CLARKSON
  • Publication number: 20230014870
    Abstract: The present invention relates to a D-galactopyranose compound of formula (1) wherein the pyranose ring is ?-D-galactopyranose, and these compounds are high affinity galectin-1 and/or galectin 3 inhibitors for use in treatment of inflammation; fibrosis; scarring; keloid formation; aberrant scar formation; surgical adhesions; septic shock; cancer; metastasising cancers; autoimmune diseases, metabolic disorders; heart disease; heart failure; pathological angiogenesis; eye diseases; atherosclerosis; metabolic diseases; diabetes type I; diabetes type II; insulin resistance; Diastolic heart failure; asthma; liver disorders.
    Type: Application
    Filed: July 3, 2020
    Publication date: January 19, 2023
    Applicant: GALECTO BIOTECH AB
    Inventor: Fredrik ZETTERBERG
  • Publication number: 20220380401
    Abstract: A compound of the general formula (1). The compound of formula (1) is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Also, a method for treatment of a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human.
    Type: Application
    Filed: July 20, 2022
    Publication date: December 1, 2022
    Applicant: GALECTO BIOTECH AB
    Inventors: Fredrik ZETTERBERG, Kristoffer PETERSON, Karl JANSSON
  • Patent number: 11447517
    Abstract: A compound of the general formula (1). The compound of formula (1) is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Also, a method for treatment of a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human.
    Type: Grant
    Filed: November 15, 2019
    Date of Patent: September 20, 2022
    Assignee: GALECTO BIOTECH AB
    Inventors: Fredrik Zetterberg, Kristoffer Peterson, Karl Jansson
  • Publication number: 20220289783
    Abstract: An embodiment of the present invention relates to a compound of the general formula. The compound of formula is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Furthermore an embodiment of the present invention concerns a method for treatment of a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human.
    Type: Application
    Filed: May 19, 2022
    Publication date: September 15, 2022
    Applicant: Galecto Biotech AB
    Inventors: Thomas BRIMERT, Richard JOHNSSON, Hakon LEFFLER, Ulf NILSSON, Fredrik ZETTERBERG
  • Publication number: 20220281909
    Abstract: A D-galactopyranose compound of formula (1) wherein the pyranose ring is ?-D-galactopyranose, and these compounds are high affinity galectin-3 inhibitors. Also, pharmaceutical compositions including these compounds. Further, a method for treatment of a disorder relating to the binding of a galectin-3 to a ligand, such as inflammation, in a mammal, such as a human, wherein a therapeutically effective amount of at least one of these compounds is administered to a mammal in need of the treatment.
    Type: Application
    Filed: July 3, 2020
    Publication date: September 8, 2022
    Applicant: GALECTO BIOTECH AB
    Inventors: Fredrik ZETTERBERG, Kristoffer PETERSON
  • Publication number: 20220259251
    Abstract: A D-galactopyranose compound of formula (1) wherein, the pyranose ring is beta-D-galactopyranose, and pharmaceutical composition including these compounds. These are high affinity galectin-1 and/or 3 inhibitors. Also, methods for treating a disorder relating to the binding of a galectin-1 and/or -3 to a ligand in which these compounds or pharmaceutical compositions are administered.
    Type: Application
    Filed: July 3, 2020
    Publication date: August 18, 2022
    Applicant: GALECTO BIOTECH AB
    Inventor: Fredrik ZETTERBERG
  • Publication number: 20220251132
    Abstract: The present invention relates to a process for preparing a compound of formula (I) wherein said process is suitable for large scale synthesis.
    Type: Application
    Filed: June 24, 2020
    Publication date: August 11, 2022
    Applicant: GALECTO BIOTECH AB
    Inventors: Fredrik ZETTERBERG, Andrew TYRELL, Ulf NILSSON, Anders BERGH, Jonathan CUMMINS, Alexander WEYMOUTH-WILSON, Robert CLARKSON
  • Patent number: 11377464
    Abstract: An embodiment of the present invention relates to a compound of the general formula. The compound of formula is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Furthermore an embodiment of the present invention concerns a method for treatment of a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human.
    Type: Grant
    Filed: September 11, 2020
    Date of Patent: July 5, 2022
    Assignee: Galecto Biotech AB
    Inventors: Thomas Brimert, Richard Johnsson, Hakon Leffler, Ulf Nilsson, Fredrik Zetterberg
  • Publication number: 20220017558
    Abstract: A compound of the general formula (1). The compound of formula (1) is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Also, a method for treatment of a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human.
    Type: Application
    Filed: November 15, 2019
    Publication date: January 20, 2022
    Applicant: GALECTO BIOTECH AB
    Inventors: Fredrik ZETTERBERG, Kristoffer PETERSON, Karl JANSSON
  • Publication number: 20210380623
    Abstract: A prodrug compound of the general formula I or II. The prodrug compound of formula I or II is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Also, a method for treatment of a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human.
    Type: Application
    Filed: October 9, 2019
    Publication date: December 9, 2021
    Applicant: GALECTO BIOTECH AB
    Inventors: Fredrik ZETTERBERG, Ulf NILSSON
  • Publication number: 20210380624
    Abstract: A compound of the general formula I or II. The compound of formula I or II is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Furthermore, a method for treatment of a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human.
    Type: Application
    Filed: October 9, 2019
    Publication date: December 9, 2021
    Applicant: GALECTO BIOTECH AB
    Inventors: Fredrik ZETTERBERG, Ulf NILSSON, Thomas BRIMERT, Kristoffer PETERSON, Karl JANSSON
  • Publication number: 20210284678
    Abstract: An ?-D-galactopyranose compound of the general formula (1). The ?-D-galactopyranose compound of formula (1) is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-1 to a ligand in a mammal, such as a human. Furthermore, a method for treatment of a disorder relating to the binding of a galectin, such as galectin-1 to a ligand in a mammal, such as a human.
    Type: Application
    Filed: May 24, 2021
    Publication date: September 16, 2021
    Applicant: GALECTO BIOTECH AB
    Inventor: Fredrik ZETTERBERG
  • Patent number: 11046725
    Abstract: An ?-D-galactopyranose compound of the general formula (1). The ?-D-galactopyranose compound of formula (1) is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-1 to a ligand in a mammal, such as a human. Furthermore, a method for treatment of a disorder relating to the binding of a galectin, such as galectin-1 to a ligand in a mammal, such as a human.
    Type: Grant
    Filed: January 9, 2019
    Date of Patent: June 29, 2021
    Assignee: GALECTO BIOTECH AB
    Inventor: Fredrik Zetterberg
  • Patent number: 10988502
    Abstract: The present invention relates to a compound of the general formula (1). The compound of formula (1) is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-1 to a ligand in a mammal, such as a human. Furthermore, the present invention concerns a method for treatment of a disorder relating to the binding of a galectin, such as galectin-1 to a ligand in a mammal, such as a human.
    Type: Grant
    Filed: July 9, 2017
    Date of Patent: April 27, 2021
    Assignee: GALECTO BIOTECH AB
    Inventors: Fredrik Zetterberg, Hakon Leffler, Ulf Nilsson