Patents by Inventor Frida Ekholm Pettersson

Frida Ekholm Pettersson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protofibril selective antibodies and the use thereof
    Patent number: 9034334
    Abstract: The invention relates to an isolated antibody, or fragment thereof, having high affinity for human A? protofibrils. The invention further relates to compositions that include the antibody, or a fragment thereof, and a pharmaceutically acceptable buffer. The invention further relates to a method of preventing or treating Alzheimer's disease, which includes the step of administering to a patient having or suspected of having Alzheimer's disease such an antibody, or fragment thereof or a composition that includes the antibody or a fragment thereof.
    Type: Grant
    Filed: August 26, 2011
    Date of Patent: May 19, 2015
    Assignee: BioArctic Neuroscience AB
    Inventors: Pär Gellerfors, Lars Lannfelt, Dag Sehlin, Frida Ekholm Pettersson, Hillevi Englund
  • PROTOFIBRIL SELECTIVE ANTIBODIES AND THE USE THEREOF
    Publication number: 20120076726
    Abstract: The invention relates to an isolated antibody, or fragment thereof, having high affinity for human A? protofibrils. The invention further relates to compositions that include the antibody, or a fragment thereof, and a pharmaceutically acceptable buffer. The invention further relates to a method of preventing or treating Alzheimer's disease, which includes the step of administering to a patient having or suspected of having Alzheimer's disease such an antibody, or fragment thereof or a composition that includes the antibody or a fragment thereof.
    Type: Application
    Filed: August 26, 2011
    Publication date: March 29, 2012
    Applicant: BIOARCTIC NEUROSCIENCE AB
    Inventors: Par GELLERFORS, Lars LANNFELT, Dag SEHLIN, Frida EKHOLM PETTERSSON, Hillevi ENGLUND
  • Protofibril selective antibodies and the use thereof
    Patent number: 8025878
    Abstract: The present invention pertains to the prevention, treatment and diagnosis of neurodegenerative diseases, in particular Alzheimer's disease, and other similar disease. More specifically to high affinity antibodies selective for amyloid beta protein (A?) in its protofibril conformation and of IgG class and IgG1 or IgG4 subclass or combinations thereof or mutations thereof, retaining high Fc receptor binding and low C1(C1q) binding, effective in clearance of A? protofibrils and with reduce risk of inflammation.
    Type: Grant
    Filed: March 23, 2007
    Date of Patent: September 27, 2011
    Assignee: BioArctic Neuroscience AB
    Inventors: Pär Gellerfors, Lars Lannfelt, Dag Sehlin, Frida Ekholm Pettersson, Hillevi Englund
  • PROTOFIBRIL SELECTIVE ANTIBODIES AND THE USE THEREOF
    Publication number: 20090258009
    Abstract: The present invention pertains to the prevention, treatment and diagnosis of neurodegenerative diseases, in particular Alzheimer's disease, and other similar disease. More specifically to high affinity antibodies selective for amyloid beta protein (A?) in its protofibril conformation and of IgG class and IgG1 or IgG4 subclass or combinations thereof or mutations thereof, retaining high Fc receptor binding and low C1(CIq) binding, effective in clearance of A? protofibrils and with reduce risk of inflammation.
    Type: Application
    Filed: March 23, 2007
    Publication date: October 15, 2009
    Inventors: Par Gellerfors, Lars Lannfelt, Dag Sehlin, Frida Ekholm Pettersson, Hillevi Englund