Patents by Inventor Fridolin Gysel

Fridolin Gysel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11911757
    Abstract: A pipetting device includes a pipetting channel at least partially filled with working gas, a pipetting tip accessible through a pipetting opening such that the volume of dosing liquid drawn into the receiving chamber can be varied by changing the pressure of the working gas in the receiving chamber, a pipetting piston for changing the pressure of the working gas and accommodated in the pipetting channel to be movable along the pipetting channel, a drive driving the pipetting piston to perform a movement along the pipetting channel, a control device controlling the drive, and a pressure sensor sensing the pressure of the working gas. The control device controls the drive to generate a pressure pulse in the pipetting channel based on the pressure signal output by the pressure sensor whereby the pressure of the working gas during the pulse follows a predefined working gas target pressure pulse curve.
    Type: Grant
    Filed: July 9, 2019
    Date of Patent: February 27, 2024
    Assignee: HAMILTON BONADUZ AG
    Inventors: Hanspeter Romer, Reto Ettinger, Fridolin Gysel, Jürg Rast, Jonas Hilti
  • Publication number: 20230211334
    Abstract: A pipetting device for outputting amounts of a dosing fluid of less than 1 ?l including a fluid volume; a pipetting plunger that can be moved along a plunger path, wherein a displacement of the pipetting plunger brings about a first pressure change in the fluid volume; a movement drive which is force-transmittingly connected to the pipetting plunger in order to drive the pipetting plunger such that it moves along the plunger path; a sound source which is designed to generate at least one sound impulse as a second pressure change in the fluid volume; and a control device which is designed to control the movement drive and the sound source, the pipetting device having a pipetting channel which extends along a channel axis and in which both the pipetting plunger is moveably accommodated along the channel axis as the plunger path and the fluid volume is accommodated, wherein the fluid volume includes a working gas which wets a plunger surface of the pipetting plunger, wherein, in addition, the sound source is des
    Type: Application
    Filed: June 7, 2021
    Publication date: July 6, 2023
    Inventors: Fridolin Gysel, Jonas Hilti
  • Publication number: 20230168267
    Abstract: A pipetting unit (2) with capacitive liquid detection comprises: a pressure tube (10); a shield (12) disposed around the pressure tube (10); a coupling (14) for temporarily attaching a pipetting tip (4) to the pipetting unit (2), wherein when the pipetting tip (4) is connected, an electrical connection is established between the pressure tube (10) and the pipetting tip (4); and an electric circuit (20) coupled to the pressure tube (10) and the shield (12), wherein the electric circuit (20) is configured to apply a time-variable electrical signal to the pressure tube (10), said time-variable electrical signal permitting a capacitive detection of a contact between the pipetting tip (4) and a pipetting liquid (112) when the pipetting tip (4) is connected, and wherein the electric circuit (20) is configured to connect the shield (12) to ground.
    Type: Application
    Filed: December 11, 2020
    Publication date: June 1, 2023
    Inventors: Fridolin GYSEL, Reto ETTINGER, Silvio WALPEN
  • Patent number: 11648566
    Abstract: A pipetting device includes pipetting unit(s), a guide assembly with at least one guide rail on which the pipetting unit(s) is guided in order to be moved along a movement axis, and a linear drive assembly, by which the pipetting unit(s) can be driven in order to be moved along the movement axis. The linear drive device has a stationary stator, and the at least one pipetting unit forms a linear drive assembly rotor which can be moved along the movement axis relative to the stator. The pipetting device also has at least two rotor magnet assemblies which interact with the same common stator magnet assembly so as to generate a drive force and which are arranged at a distance from one another along a spacing axis that is orthogonal to the movement axis. The common stator magnet assembly is located between the at least two rotor magnet assemblies.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: May 16, 2023
    Assignee: HAMILTON BONADUZ AG
    Inventors: Hanspeter Romer, Silvio Walpen, Fridolin Gysel
  • Patent number: 11539271
    Abstract: There is provided a method for contactless determination of the position of a driven moving portion (4) of an electric motor (2) by means of a plurality of magnetic field sensors (8), wherein the moving portion is movably arranged with respect to a stator (6) and has a plurality of permanent magnets (40) which generate a moving-portion magnetic field having a plurality of periodically spaced apart maxima, and wherein the plurality of magnetic field sensors are arranged along a movement path (43) of the moving portion.
    Type: Grant
    Filed: May 3, 2018
    Date of Patent: December 27, 2022
    Assignee: HAMILTON BONADUZ AG
    Inventors: Reto Ettinger, Jürg Rast, Fridolin Gysel
  • Patent number: 11504708
    Abstract: A pipetting apparatus and method for pulsed dispensing of small metered-liquid doses of no more than 1 ?l. The apparatus includes a pipetting conduit at least partly filled with working gas, a pressure-modifying apparatus for modifying the pressure of the working gas, and a control apparatus for applying control to the pressure-modifying apparatus. The control apparatus can control the pressure-modifying apparatus so as to generate in the pipetting conduit, with respect to a reference holding pressure in the pipetting conduit which is necessary for immovable holding of the metered-liquid quantity, an overpressure pulse having a pulse duration of no more than 40 ms.
    Type: Grant
    Filed: December 11, 2017
    Date of Patent: November 22, 2022
    Assignee: HAMILTON BONADUZ AG
    Inventors: Hanspeter Romer, Reto Ettinger, Fridolin Gysel, Jürg Rast, Jonas Hilti
  • Publication number: 20210154659
    Abstract: A pipetting device includes a pipetting channel at least partially filled with working gas, a pipetting tip which is accessible through a pipetting opening such that the volume of dosing liquid drawn into the receiving chamber through the pipetting opening can be varied by changing the pressure of the working gas in the receiving chamber, a pipetting piston for changing the pressure of the working gas and accommodated in the pipetting channel so as to be movable along the pipetting channel, a drive for driving the pipetting piston to perform a movement along the pipetting channel, a control device for controlling the drive, and a pressure sensor for sensing the pressure of the working gas. The control device controls the drive to generate a pressure pulse in the pipetting channel based on the pressure signal output by the pressure sensor such that the pressure of the working gas during the pulse follows a predefined working gas target pressure pulse curve.
    Type: Application
    Filed: July 9, 2019
    Publication date: May 27, 2021
    Inventors: Hanspeter Romer, Reto Ettinger, Fridolin Gysel, Jürg Rast, Jonas Hilti
  • Publication number: 20210078010
    Abstract: A pipetting device includes pipetting unit(s), a guide assembly with at least one guide rail on which the pipetting unit(s) is guided in order to be moved along a movement axis, and a linear drive assembly, by which the pipetting unit(s) can be driven in order to be moved along the movement axis. The linear drive device has a stationary stator, and the at least one pipetting unit forms a linear drive assembly rotor which can be moved along the movement axis relative to the stator. The pipetting device also has at least two rotor magnet assemblies which interact with the same common stator magnet assembly so as to generate a drive force and which are arranged at a distance from one another along a spacing axis that is orthogonal to the movement axis. The common stator magnet assembly is located between the at least two rotor magnet assemblies.
    Type: Application
    Filed: November 19, 2018
    Publication date: March 18, 2021
    Applicant: Hamilton Bonaduz AG
    Inventors: Hanspeter Romer, Silvio Walpen, Fridolin Gysel
  • Publication number: 20200360916
    Abstract: The present invention relates to a pipette device with a pipette channel which extends along a channel axis defining an axial direction and which passes through a channel component arrangement which, at a coupling longitudinal end, has a coupling configuration for the releasable coupling of a pipette tip. The coupling configuration has a locking component with a radially outwardly facing engagement surface arrangement, which is movable between a locking position more radially remote from the channel axis and an unlocking position lying radially closer to the channel axis. The coupling configuration has a sealing component separate from the locking component, and that the actuator drive has a switchable magnetic field source and a reaction component which is movable by the locally changing magnetic field thereof and which is connected to the locking actuator in such a way as to transmit movement.
    Type: Application
    Filed: November 8, 2018
    Publication date: November 19, 2020
    Applicant: Hamilton Bonaduz AG
    Inventors: Silvio Walpen, Fridolin Gysel
  • Publication number: 20200298242
    Abstract: A pipetting device includes pipetting unit(s), a guide assembly with at least one guide rail on which the pipetting unit(s) is guided in order to be moved along a movement axis, and a linear drive assembly, by which the pipetting unit(s) can be driven in order to be moved along the movement axis. The linear drive device has a stationary stator, and the at least one pipetting unit forms a linear drive assembly rotor which can be moved along the movement axis relative to the stator. The pipetting device also has at least two rotor magnet assemblies which interact with the same common stator magnet assembly so as to generate a drive force and which are arranged at a distance from one another along a spacing axis that is orthogonal to the movement axis. The common stator magnet assembly is located between the at least two rotor magnet assemblies.
    Type: Application
    Filed: November 19, 2018
    Publication date: September 24, 2020
    Applicant: Hamilton Bonaduz AG
    Inventors: Hanspeter Romer, Silvio Walpen, Fridolin Gysel
  • Publication number: 20200298225
    Abstract: An integrated motor cartridge (2) for connection to and for use in a pipetting system comprises a housing (4); a guide tube (14); a piston (16) provided with a plurality of permanent magnets (18), the piston having a pressure tube facing side and a pressure tube distal side, the piston being arranged in the guide tube and the piston having at least one seal (24) with respect to the guide tube; and a coil assembly (20) by means of which the piston can be moved in the guide tube when power is supplied to the coil assembly; wherein the guide tube, the piston and the coil assembly are arranged in the housing.
    Type: Application
    Filed: July 2, 2018
    Publication date: September 24, 2020
    Inventors: Hanspeter ROMER, Fridolin GYSEL, Silvio WALPEN, Reto ETTINGER
  • Publication number: 20200282390
    Abstract: The present invention relates to a pipetting apparatus for aspirating and dispensing metered liquids, encompassing: at least one guidance tube (30) extending along a cylinder axis (Z), the cylinder axis (Z) defining: an axial direction proceeding along its direction of extent; a radial direction proceeding orthogonally thereto; and a circumferential direction extending therearound; a piston (10) received in the guidance tube (30) axially movably relative thereto; a coupling configuration embodied for temporary or permanent coupling of a pipetting tip; and a drive apparatus (32) for driving the piston (10) to move axially relative to the guidance tube (30), the guidance tube (30) comprising a coupling-side longitudinal end (48) that is located closer to the coupling configuration; and comprising a servicing-side longitudinal end (50) that is located oppositely from the coupling-side longitudinal end (48) and is located farther from the coupling configuration; the piston (10) encompassing at least one pe
    Type: Application
    Filed: October 11, 2017
    Publication date: September 10, 2020
    Applicant: Hamilton Bonaduz AG
    Inventors: Hanspeter Romer, Reto Ettinger, Fridolin Gysel, Heidi Cattaneo
  • Patent number: 10632460
    Abstract: A pipetting device has a pipetting channel extending along a channel path, in which a piston is accommodated to be movable along the channel path to change the pressure of a working gas that wets the piston on a dosing side facing the dosing liquid. The pipetting device includes a movement drive for driving the piston along the channel path and a control unit configured to operate the movement drive for pipetting a predetermined single dosing volume of less than 5 ?l with the piston moving in the pipetting direction and its dosing side end face sweeping over a pipetting volume which is not less than 1.4 times greater than the single dosing volume, and subsequently moving in a counter pipetting direction and its dosing side end face sweeping over a counter pipetting volume, wherein not more than 50 ms elapse between beginning control signals.
    Type: Grant
    Filed: July 26, 2016
    Date of Patent: April 28, 2020
    Assignee: Hamilton Bonaduz AG
    Inventors: Hanspeter Romer, Fridolin Gysel, Urs Lendenmann
  • Publication number: 20200076275
    Abstract: There is provided a method for contactless determination of the position of a driven moving portion (4) of an electric motor (2) by means of a plurality of magnetic field sensors (8), wherein the moving portion is movably arranged with respect to a stator (6) and has a plurality of permanent magnets (40) which generate a moving-portion magnetic field having a plurality of periodically spaced apart maxima, and wherein the plurality of magnetic field sensors are arranged along a movement path (43) of the moving portion.
    Type: Application
    Filed: May 3, 2018
    Publication date: March 5, 2020
    Inventors: Reto ETTINGER, Jürg RAST, Fridolin GYSEL
  • Publication number: 20190358626
    Abstract: A pipetting apparatus and method for pulsed dispensing of small metered-liquid doses of no more than 1 ?l. The apparatus includes a pipetting conduit at least partly filled with working gas, a pressure-modifying apparatus for modifying the pressure of the working gas, and a control apparatus for applying control to the pressure-modifying apparatus. The control apparatus can control the pressure-modifying apparatus so as to generate in the pipetting conduit, with respect to a reference holding pressure in the pipetting conduit which is necessary for immovable holding of the metered-liquid quantity, an overpressure pulse having a pulse duration of no more than 40 ms.
    Type: Application
    Filed: December 11, 2017
    Publication date: November 28, 2019
    Applicant: Hamilton Bonaduz AG
    Inventors: Hanspeter Romer, Reto Ettinger, Fridolin Gysel, Jürg Rast, Jonas Hilti
  • Publication number: 20190255522
    Abstract: The present invention relates to a pipetting apparatus for aspirating and dispensing metered liquids, encompassing: at least one guidance tube (30) extending along a cylinder axis (Z), the cylinder axis (Z) defining: an axial direction proceeding along its direction of extent; a radial direction proceeding orthogonally thereto; and a circumferential direction extending therearound; a piston (10) received in the guidance tube (30) axially movably relative thereto; a coupling configuration embodied for temporary or permanent coupling of a pipetting tip; and a drive apparatus (32) for driving the piston (10) to move axially relative to the guidance tube (30), the guidance tube (30) comprising a coupling-side longitudinal end (48) that is located closer to the coupling configuration; and comprising a servicing-side longitudinal end (50) that is located oppositely from the coupling-side longitudinal end (48) and is located farther from the coupling configuration; the piston (10) encompassing at least one pe
    Type: Application
    Filed: October 11, 2017
    Publication date: August 22, 2019
    Applicant: Hamilton Bonaduz AG
    Inventors: Hanspeter Romer, Reto Ettinger, Fridolin Gysel, Heidi Cattaneo
  • Publication number: 20180185836
    Abstract: A pipetting device has a pipetting channel extending along a channel path, in which a piston is accommodated to be movable along the channel path to change the pressure of a working gas that wets the piston on a dosing side facing the dosing liquid. The pipetting device includes a movement drive for driving the piston along the channel path and a control unit configured to operate the movement drive for pipetting a predetermined single dosing volume of less than 5 ?l with the piston moving in the pipetting direction and its dosing side end face sweeping over a pipetting volume which is not less than 1.4 times greater than the single dosing volume, and subsequently moving in a counter pipetting direction and its dosing side end face sweeping over a counter pipetting volume, wherein not more than 50 ms elapse between beginning control signals.
    Type: Application
    Filed: July 26, 2016
    Publication date: July 5, 2018
    Inventors: Hanspeter Romer, Fridolin Gysel