Patents by Inventor Friedhelm L. Brinkhaus

Friedhelm L. Brinkhaus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enhanced carotenoid accumulation in storage organs of genetically engineered plants
    Patent number: 5618988
    Abstract: A transgenic higher plant, seed containing the transgene, and methods of providing enhanced carotenoid accumulation are disclosed. The transgenic higher plant has a genomic structural gene that encodes a chimeric polypeptide conjugate and over accumulates a colored native carotenoid in a preselected storage organ relative to the accumulation in a non-transgenic plant of the same type. Expression of the chimeric polypeptide is driven by a promoter operatively linked to that structural gene that provides storage organ-enhanced expression. The chimeric polypeptide has an N-terminal plastid transit peptide portion whose C-terminus is linked to the N-terminus of a non-higher plant phytoene synthase enzyme.
    Type: Grant
    Filed: October 28, 1994
    Date of Patent: April 8, 1997
    Assignee: Amoco Corporation
    Inventors: Randal Hauptmann, William H. Eschenfeldt, Jami English, Friedhelm L. Brinkhaus
  • Phytoene biosynthesis in genetically engineered hosts
    Patent number: 5545816
    Abstract: DNA segments encoding the Erwinia herbicola enzymes geranylgeranyl pyrophosphate (GGPP) synthase and phytoene synthase, vectors containing those DNA segments, host cells containing the vectors and methods for producing those enzymes and phytoene by recombinant DNA technology in transformed host organisms are disclosed.
    Type: Grant
    Filed: July 19, 1993
    Date of Patent: August 13, 1996
    Assignee: Amoco Corporation
    Inventors: Rodney L. Ausich, Friedhelm L. Brinkhaus, Indrani Mukharji, John Proffitt, James Yarger, Huei-Che B. Yen
  • Lycopene biosynthesis in genetically engineered hosts
    Patent number: 5530189
    Abstract: DNA segments encoding the Erwinia enzymes geranylgeranyl pyrophosphate (GGPP) synthase, phytoene synthase and phytoene dehydrogenase-4H, vectors containing those DNA segments, host cells containing the vectors and methods for producing those enzymes and lycopene by recombinant DNA technology in transformed host organisms are disclosed.
    Type: Grant
    Filed: July 22, 1993
    Date of Patent: June 25, 1996
    Assignee: Amoco Corporation
    Inventors: Rodney L. Ausich, Friedhelm L. Brinkhaus, Indrani Mukharji, John Proffitt, James Yarger, Huei-Che B. Yen
  • Beta-carotene biosynthesis in genetically engineered hosts
    Patent number: 5530188
    Abstract: DNA segments encoding the Erwinia herbicola enzymes geranylgeranyl pyrophosphate (GGPP) synthase, phytoene synthase, phytoene dehydrogenase-4H and lycopene cyclase, vectors containing those DNA segments, host cells containing the vectors and methods for producing those enzymes and beta-carotene by recombinant DNA technology in transformed host organisms are disclosed.
    Type: Grant
    Filed: July 21, 1993
    Date of Patent: June 25, 1996
    Assignee: Amoco Corporation
    Inventors: Rodney L. Ausich, Friedhelm L. Brinkhaus, Indrani Mukharji, John Proffitt, James Yarger, Huei-Che B. Yen