Patents by Inventor Friedmann Paul

Friedmann Paul has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-acetyl glucosamine as a biomarker of MS disease course
    Patent number: 10495646
    Abstract: The invention provides the art with a powerful diagnostic method of distinguishing relapse-remitting MS subjects from progressive MS subjects, based on the measurement of serum concentrations of N-acetylglucosamine (GlcNAc,), for the first time enabling rapid diagnosis of the progressive form of MS. GlcNAc serum concentration can also be used to assess neurodegenerative status and MS progression in subjects suffering from MS or other neurological conditions. The methods of the invention also allow for the identification of new therapeutics for MS and other neurological conditions and also enables the personalized efficacy assessment of a potential therapy for an MS subject.
    Type: Grant
    Filed: January 29, 2016
    Date of Patent: December 3, 2019
    Assignees: The Regents of the University of California, Charite-Universitatsmedizin Berlin, Mt. Sinai Hospital
    Inventors: Michael Demetriou, Alexander Brandt, Friedmann Paul, James Dennis