Patents by Inventor Friedrich Gotz

Friedrich Gotz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200377405
    Abstract: A transparent article made of glass ceramic with high surface quality as well as a method producing are provided. The article is suitable for use as a viewing pane. The method includes the steps of: producing a melt with a raw material composition that is suitable for a ceramization; hot shaping a flat substrate made of ceramizable green glass having two oppositely arranged, essentially flat surfaces from the melt; processing of at least one of the surfaces of the substrate with a smoothing fine-treatment process; ceramizing the substrate to produce the article made of glass ceramic.
    Type: Application
    Filed: August 19, 2020
    Publication date: December 3, 2020
    Applicant: SCHOTT AG
    Inventors: Helga Gotz, Kyuchul Chung, Marcus Datz, Rolf Hansen, Friedrich-Georg Schroder
  • Patent number: 6821755
    Abstract: The invention relates to advantageous processes for preparing heterologous proteins in prokaryotic host cells by improved codon use and/or expression of tRNAs which code for codons occurring rarely in said host cell.
    Type: Grant
    Filed: July 27, 2001
    Date of Patent: November 23, 2004
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Rolf-Günther Werner, Klaus Bergemann, Friedrich Götz, Andreas Peschel
  • Publication number: 20030143563
    Abstract: A method for identifying a nucleic acid which codes for a polypeptide factor affecting the covalent bonding of polypeptides to the surface of Gram-positive bacteria, comprising the following steps:
    Type: Application
    Filed: July 23, 2002
    Publication date: July 31, 2003
    Applicant: Evotec BioSystems AG of Schnackenburgallee 114
    Inventors: Andreas Strauss, Gunther Thumm, Johannes Pohlner, Friedrich Gotz
  • Patent number: 6566062
    Abstract: A method for identifying a nucleic acid which codes for a polypeptide factor affecting the covalent bonding of polypeptides to the surface of Gram-positive bacteria, comprising the following steps: a) providing a sample of Gram-positive bacteria which can be genetically altered and contain or produce at least one enzymatic reporter substance which is or can become covalently bonded to the surface of the Gram-positive bacteria, said at least one reporter substance having a different enzymatic activity when not covalently bonded to the surface of the Gram-positive bacteria from that exhibited when it is covalently bonded to the surface of the Gram-positive bacteria; b) causing genetic alterations in Gram-positive bacteria of the sample; c) assaying the enzymatic activity of the reporter substance of the Gram-positive bacteria of the sample; d) separating Gram-positive bacteria which exhibit a different enzymatic activity of the reporter substance from that observed for covalent bonding of the reporter subst
    Type: Grant
    Filed: May 2, 2000
    Date of Patent: May 20, 2003
    Assignee: Evotec BioSystems AG
    Inventors: Andreas Strauss, Gunther Thumm, Johannes Pohlner, Friedrich Götz
  • Publication number: 20030017531
    Abstract: The invention relates to advantageous processes for preparing heterologous proteins in prokaryotic host cells by improved codon use and/or expression of tRNAs which code for codons occurring rarely in said host cell.
    Type: Application
    Filed: July 27, 2001
    Publication date: January 23, 2003
    Inventors: Rolf-Gunther Werner, Klaus Bergemann, Friedrich Gotz, Andreas Peschel
  • Patent number: 5962253
    Abstract: A method is described for oxidatively decarboxylating a peptide, comprising combining a peptide with EpiD, wherein the peptide comprises at its carboxy terminus the amino acid sequence X.sub.1 X.sub.2 X.sub.3 X.sub.4 X.sub.5 X.sub.6 C, wherein X.sub.1, X.sub.2, X.sub.3 and X.sub.4 are any one of the twenty common amino acids, X.sub.5 is Tyr, Val, Met, Leu, Ile, Phe or Trp, and X.sub.6 is Cys, Ala, Ser, Val, or Thr, whereby the oxidative decarboxylation of the peptide occurs.
    Type: Grant
    Filed: May 13, 1996
    Date of Patent: October 5, 1999
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Thomas Kupke, Friedrich Gotz, Christoph Kempter, Gunther Jung
  • Patent number: 5843709
    Abstract: A bacterial host is described which is transformed by a plasmid coding for a polypeptide precursor wherein the host comprises a multi-enzyme complex capable of reacting with the expressed polypeptide precursor to produce a polypeptide comprising at least one dehydroamino acid and/or at least one lanthione bridge. A process for producing a polypeptide comprising at least one dehydroamino acid and/or at least one lanthione bridge, such as gallidermin, is also described. A plasmid capable of transforming a bacterial host is additionally described.Also disclosed are recombinant DNA molecules which specify Epi B, Epi C, Epi D, Epi P and Epi Q, enzymes which are involved in the biosynthesis of lantibiotic epidermin.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 1, 1998
    Assignee: Dr. Karl Thomae GmbH
    Inventors: Karl-Dieter Entian, Friedrich Gotz, Norbert Schnell, Johannes Augustin, Germar Engelke, Ralf Rosenstein, Cortina Kaletta, Cora Klein, Bernd Wieland, Thomas Kupke, Gunther Jung, Roland Kellner
  • Patent number: 5837485
    Abstract: A bacterial host is described which is transformed by a plasmid coding for a polypeptide precursor wherein the host comprises a multi-enzyme complex capable of reacting with the expressed polypeptide precursor to produce a polypeptide comprising at least one dehydroamino acid and/or at least one lanthionine bridge. A process for producing a polypeptide comprising at least one dehydroamino acid and/or at least one lanthionine bridge, such as gallidermin, is also described. A plasmid capable of transforming a bacterial host is additionally described.Also disclosed are recombinant DNA molecules which specify Epi B, Epi C, Epi D, Epi P and Epi Q, enzymes which are involved in the biosynthesis of lantibiotic epidermin.
    Type: Grant
    Filed: February 22, 1995
    Date of Patent: November 17, 1998
    Assignee: Dr. Karl Tomae GmbH
    Inventors: Karl-Dieter Entian, Friedrich Gotz, Norbert Schnell, Johannes Augustin, Germar Engelke, Ralf Rosenstein, Cortina Kaletta, Cora Klein, Bernd Wieland, Thomas Kupke, Gunther Jung, Roland Kellner
  • Patent number: 5231013
    Abstract: A new polycyclic peptide antibiotic termed gallidermin is disclosed and described, together with a process for producing such antibiotic by fermination of a new microorganism, Staphylococcus gallinarum (DSM 4616).
    Type: Grant
    Filed: May 18, 1989
    Date of Patent: July 27, 1993
    Inventors: Gunther Jung, Roland Kellner, Hans Zahner, Friedrich Gotz, Thomas Horner, Rolf G. Werner, Hermann Allgaier
  • Patent number: 5194402
    Abstract: In the process described, the electronic circuits (2) for the signal processing and the sensor structures to which they are coupled are manufactured side by side on the common substrate (1). The process is characterized by the following steps: manufacture of the electronic circuits on the substrate (1) by known semiconductor techniques; application to the surface of the substrate (1) of a galvanic electrode layer (7), which may or may not be structured; application on the substrate surface containing the electrode layer of an X-ray resist layer (8), the thickness of which corresponds to a characteristic height of the sensor structures to be produced; production of negatives (10, 11) of the sensor structures in this resist layer (8) by X-ray lithography: galvanic deposition of a metal (12, 13) or a metal alloy in the negatives (10, 11) of the sensor structures using the galvanic electrode layer; division of the substrate with the sensor structures applied thereto into separate functional units or chips.
    Type: Grant
    Filed: April 10, 1989
    Date of Patent: March 16, 1993
    Assignee: Kernforschungszentrum Karlsruhe GmbH
    Inventors: Wolfgang Ehrfeld, Friedrich Gotz, Werner Schelb, Dirk Schmidt
  • Patent number: 5175101
    Abstract: The invention concerns a DNA which contains(1) at least one of the two regions of the nucleotide sequence SEQ ID NO:1 coding for a protein with a Sau3AI methylase activity or for a protein with a Sau3AI endonuclease activity.(2) a sequence corresponding to the DNA from (1) within the scope of the degeneration of the genetic code or(3) a sequence which hybridizes under stringent hybridization conditions with a DNA from (1) or (2).In addition a vector is disclosed which contains a DNA according to the present invention, in particular under the control of a regulatable closed promoter, as well as microorganisms which are transformed with one or several vectors according to the present invention and the isolation of recombinant Sau3AI endonuclease from the transformed microorganisms.
    Type: Grant
    Filed: June 10, 1991
    Date of Patent: December 29, 1992
    Assignee: Boehringer Mannheim GmbH
    Inventors: Friedrich Gotz, Stefan Seeber
  • Patent number: 4666832
    Abstract: The present invention provides a new pyruvate oxidase which decarboxylates pyruvate with the formation of hydrogen peroxide, characterized in that it is active without the addition of FAD, TPP and divalent metal ions.The present invention also provides a process for preparing this new enzyme and a reagent containing it.
    Type: Grant
    Filed: February 27, 1984
    Date of Patent: May 19, 1987
    Assignee: Boehringer Mannheim GmbH
    Inventors: Erich Elstner, Karl-Heinz Schleifer, Friedrich Gotz, Barbara Sedewitz, Albert Roder, Hans Mollering, Hans Seidel
  • Patent number: 3990962
    Abstract: Plural concentric, tubular electrodes are disposed in a cylindrical pressure vessel to establish therein plural, at least, partially serially connected cells in radial, spaced-apart relation. The tubular electrodes are either mounted in an insulative bottom layer of the vessel, or when closed at their lower axial ends, are nested with spacers inbetween. Various provisions are made for cooling and for equalizing the electric current density in the several cells or the volume of the cells is kept similar.
    Type: Grant
    Filed: September 26, 1974
    Date of Patent: November 9, 1976
    Inventor: Friedrich Gotz